Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | concentrative Na+ nucleoside cotransporter | 0.0346 | 0.3076 | 1 |
Echinococcus granulosus | concentrative Na nucleoside cotransporter | 0.0346 | 0.3076 | 1 |
Echinococcus multilocularis | solute carrier family 28 | 0.0346 | 0.3076 | 1 |
Wolbachia endosymbiont of Brugia malayi | phospho-N-acetylmuramoyl-pentapeptide-transferase | 0.0882 | 1 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0108 | 0 | 0.5 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0108 | 0 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0108 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.0807 | 1 |
Treponema pallidum | phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) | 0.0335 | 0.2934 | 0.5 |
Chlamydia trachomatis | phospho-N-acetylmuramoyl-pentapeptide-transferase | 0.0335 | 0.2934 | 1 |
Echinococcus multilocularis | geminin | 0.0171 | 0.0807 | 0.2625 |
Giardia lamblia | Glycogen phosphorylase | 0.0108 | 0 | 0.5 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0108 | 0 | 0.5 |
Echinococcus multilocularis | sodium:nucleoside cotransporter 2 | 0.0226 | 0.1519 | 0.4939 |
Echinococcus granulosus | geminin | 0.0171 | 0.0807 | 0.2625 |
Echinococcus granulosus | solute carrier family 28 | 0.0346 | 0.3076 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0108 | 0 | 0.5 |
Echinococcus granulosus | Na+ dependent nucleoside transporter | 0.0346 | 0.3076 | 1 |
Brugia malayi | carbohydrate phosphorylase | 0.0108 | 0 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0108 | 0 | 0.5 |
Mycobacterium ulcerans | phospho-N-acetylmuramoyl-pentapeptide-transferase | 0.0882 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable phospho-N-acetylmuramoyl-pentappeptidetransferase MurX | 0.0882 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.0807 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.