Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.3213 | 0.3139 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0076 | 1 | 1 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0014 | 0.0706 | 0.7455 |
Toxoplasma gondii | P-type ATPase4, putative | 0.0015 | 0.091 | 1 |
Echinococcus multilocularis | Na+:K+ ATPase alpha subunit | 0.0039 | 0.4509 | 0.4093 |
Giardia lamblia | Potassium-transporting ATPase alpha chain 1 | 0.0039 | 0.4509 | 1 |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0014 | 0.0706 | 0.7755 |
Brugia malayi | Membrane calcium atpase protein 3 | 0.0015 | 0.091 | 0.2018 |
Echinococcus multilocularis | nervana 2 | 0.0076 | 1 | 1 |
Echinococcus multilocularis | plasma membrane calcium transporting ATPase | 0.0015 | 0.091 | 0.022 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0706 | 0.0605 |
Trypanosoma cruzi | calcium motive p-type ATPase, putative | 0.0015 | 0.091 | 1 |
Echinococcus multilocularis | Tetracycline resistance leader peptide, TetL | 0.0015 | 0.091 | 0.022 |
Trypanosoma cruzi | calcium motive p-type ATPase, putative | 0.0015 | 0.091 | 1 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0076 | 1 | 1 |
Plasmodium falciparum | non-SERCA-type Ca2+ -transporting P-ATPase | 0.0015 | 0.091 | 0.5 |
Trypanosoma brucei | calcium motive p-type ATPase, putative | 0.0015 | 0.091 | 1 |
Echinococcus multilocularis | Ca2+ transporting ATPase plasma membrane | 0.0015 | 0.091 | 0.022 |
Echinococcus granulosus | plasma membrane calcium transporting ATPase | 0.0015 | 0.091 | 0.022 |
Echinococcus multilocularis | nervana 2 | 0.0076 | 1 | 1 |
Schistosoma mansoni | transmemberane protein | 0.0076 | 1 | 1 |
Echinococcus multilocularis | calcium transporting ATPase type 2C member | 0.0015 | 0.091 | 0.022 |
Brugia malayi | Na,K-ATPase alpha subunit | 0.0039 | 0.4509 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.2593 | 0.2512 |
Leishmania major | calcium motive p-type ATPase, putative | 0.0015 | 0.091 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 1 | 1 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0076 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 1 | 1 |
Echinococcus granulosus | sodium:potassium transporting ATPase subunit | 0.0076 | 1 | 1 |
Onchocerca volvulus | 0.0076 | 1 | 1 | |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0076 | 1 | 1 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0076 | 1 | 1 |
Leishmania major | calcium-transporting ATPase, putative | 0.0015 | 0.091 | 1 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase 2 | 0.0014 | 0.0706 | 0.7455 |
Brugia malayi | Probable calcium-transporting ATPase KIAA0703 | 0.001 | 0.0107 | 0.0238 |
Echinococcus granulosus | nervana 2 | 0.0076 | 1 | 1 |
Schistosoma mansoni | calcium-transporting atpase 2 (atpase 2) | 0.0015 | 0.091 | 0.022 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0076 | 1 | 1 |
Loa Loa (eye worm) | sodium/potassium-transporting ATPase subunit alpha | 0.0034 | 0.3707 | 0.3639 |
Echinococcus granulosus | nervana 2 | 0.0076 | 1 | 1 |
Echinococcus granulosus | calcium transporting atpase | 0.0015 | 0.091 | 0.022 |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0014 | 0.0706 | 0.7755 |
Brugia malayi | Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type | 0.0015 | 0.091 | 0.2018 |
Echinococcus multilocularis | calcium transporting atpase | 0.0015 | 0.091 | 0.022 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0015 | 0.091 | 1 |
Leishmania major | P-type ATPase, putative | 0.0015 | 0.091 | 1 |
Echinococcus granulosus | Ca2 transporting ATPase plasma membrane | 0.0015 | 0.091 | 0.022 |
Echinococcus granulosus | Na:K ATPase alpha subunit | 0.0039 | 0.4509 | 0.4093 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0076 | 1 | 1 |
Schistosoma mansoni | calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) | 0.0015 | 0.091 | 0.022 |
Toxoplasma gondii | plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 | 0.0015 | 0.091 | 1 |
Brugia malayi | Sodium/potassium-transporting ATPase alpha chain, putative | 0.0034 | 0.3707 | 0.822 |
Mycobacterium ulcerans | metal cation transporter p-type ATPase a | 0.0038 | 0.4305 | 1 |
Mycobacterium leprae | PROBABLE CATION-TRANSPORTER ATPASE I CTPI | 0.0032 | 0.3503 | 0.5 |
Echinococcus multilocularis | sodium:potassium transporting ATPase subunit | 0.0076 | 1 | 1 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0076 | 1 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0076 | 1 | 1 |
Schistosoma mansoni | plasma membrane calcium-transporting atpase | 0.0015 | 0.091 | 0.022 |
Plasmodium falciparum | calcium-transporting ATPase | 0.0015 | 0.091 | 0.5 |
Plasmodium vivax | P-type ATPase4, putative | 0.0015 | 0.091 | 0.5 |
Trypanosoma brucei | calcium-translocating P-type ATPase | 0.0015 | 0.091 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0076 | 1 | 1 |
Schistosoma mansoni | sodium / potassium ATPase beta chain | 0.0076 | 1 | 1 |
Schistosoma mansoni | na+/k+ atpase alpha subunit | 0.0039 | 0.4509 | 0.4093 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0014 | 0.0706 | 0.7455 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase 1 | 0.0014 | 0.0706 | 0.7455 |
Entamoeba histolytica | calcium-transporting P-type ATPase, putative | 0.0015 | 0.091 | 1 |
Plasmodium vivax | calcium-transporting ATPase, putative | 0.0015 | 0.091 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.2303 | 0.2219 |
Echinococcus granulosus | nervana 2 | 0.0076 | 1 | 1 |
Schistosoma mansoni | plasma membrane calcium-transporting atpase | 0.0015 | 0.091 | 0.022 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0015 | 0.091 | 1 |
Schistosoma mansoni | calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) | 0.0015 | 0.091 | 0.022 |
Echinococcus granulosus | calcium transporting ATPase type 2C member | 0.0015 | 0.091 | 0.022 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase, putative | 0.0014 | 0.0706 | 0.7455 |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0014 | 0.0706 | 0.7755 |
Onchocerca volvulus | 0.0076 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.4509 | 0.445 |
Trypanosoma cruzi | Calcium ATPase SERCA-like | 0.0014 | 0.0706 | 0.7455 |
Echinococcus granulosus | nervana 2 | 0.0076 | 1 | 1 |
Echinococcus granulosus | plasma membrane calcium transporting ATPase 2 | 0.0015 | 0.091 | 0.022 |
Loa Loa (eye worm) | Na,K-ATPase alpha subunit | 0.0039 | 0.4509 | 0.445 |
Toxoplasma gondii | sarco/endoplasmic reticulum Ca2+-ATPase | 0.0015 | 0.091 | 1 |
Schistosoma mansoni | Na+/K+ transporting ATPase subunit alpha | 0.0039 | 0.4509 | 0.4093 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 16420033 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.