Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | FK506 binding protein 1A, 12kDa | Starlite/ChEMBL | References |
Species | Potential target | Known druggable target | Length | Alignment span | Identity |
---|---|---|---|---|---|
Trypanosoma brucei | macrophage infectivity potentiator, precursor, putative | FK506 binding protein 1A, 12kDa | 108 aa | 107 aa | 48.6 % |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0783 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0585 | 0.6601 | 0.6601 |
Echinococcus multilocularis | glutamate receptor 2 | 0.071 | 0.8747 | 0.8747 |
Echinococcus multilocularis | glutamate receptor subunit protein glur | 0.0485 | 0.4899 | 0.4899 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0585 | 0.6601 | 0.6601 |
Echinococcus granulosus | glutamate receptor 1 | 0.0342 | 0.2455 | 0.2455 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0783 | 1 | 1 |
Echinococcus multilocularis | glutamate receptor ionotropic kainate | 0.0286 | 0.1501 | 0.1501 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0368 | 0.2908 | 0.2908 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0783 | 1 | 1 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0368 | 0.2908 | 0.2908 |
Brugia malayi | Glutamate receptor 1 precursor | 0.071 | 0.8747 | 0.5 |
Echinococcus granulosus | glutamate receptor ionotropic kainate | 0.0286 | 0.1501 | 0.1501 |
Echinococcus granulosus | glutamate receptor 2 | 0.064 | 0.7556 | 0.7556 |
Echinococcus granulosus | glutamate receptor subunit protein glur | 0.0485 | 0.4899 | 0.4899 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0585 | 0.6601 | 0.6601 |
Schistosoma mansoni | glutamate receptor kainate | 0.0511 | 0.5349 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0585 | 0.6601 | 0.6601 |
Echinococcus granulosus | glutamate receptor ionotropic kainate 3 | 0.0286 | 0.1501 | 0.1501 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0442 | 0.4161 | 0.5134 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0585 | 0.6601 | 0.6601 |
Echinococcus multilocularis | glutamate receptor 4 | 0.0342 | 0.2455 | 0.2455 |
Schistosoma mansoni | glutamate receptor kainate | 0.0511 | 0.5349 | 1 |
Echinococcus multilocularis | NMDA receptor | 0.0286 | 0.1501 | 0.1501 |
Brugia malayi | Glutamate receptor 2 precursor | 0.071 | 0.8747 | 0.5 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0341 | 0.244 | 0.244 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0368 | 0.2908 | 0.072 |
Echinococcus granulosus | glutamate receptor 4 | 0.0342 | 0.2455 | 0.2455 |
Echinococcus multilocularis | glutamate receptor 2 | 0.064 | 0.7556 | 0.7556 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.071 | 0.8747 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0585 | 0.6601 | 0.6601 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.