Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | melanocortin 4 receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.039 | 0.0819 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Leishmania major | cathepsin L-like protease | 0.0565 | 0.2575 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0565 | 0.2575 | 0.2575 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0565 | 0.2575 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0565 | 0.2575 | 0.2575 |
Onchocerca volvulus | Cathepsin L homolog | 0.0565 | 0.2575 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0565 | 0.2575 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0496 | 0.188 | 0.5 |
Echinococcus multilocularis | cysteine protease | 0.0565 | 0.2575 | 0.2575 |
Leishmania major | cathepsin L-like protease | 0.0565 | 0.2575 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0496 | 0.188 | 0.5 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0565 | 0.2575 | 0.2575 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0565 | 0.2575 | 0.2575 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0565 | 0.2575 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0496 | 0.188 | 0.188 |
Onchocerca volvulus | 0.0565 | 0.2575 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1304 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0565 | 0.2575 | 0.1912 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0565 | 0.2575 | 0.2575 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0565 | 0.2575 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0496 | 0.188 | 0.188 |
Loa Loa (eye worm) | hypothetical protein | 0.0565 | 0.2575 | 0.1912 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0565 | 0.2575 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1304 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.1304 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0565 | 0.2575 | 1 |
Echinococcus multilocularis | cathepsin b | 0.1304 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0565 | 0.2575 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0565 | 0.2575 | 0.2575 |
Entamoeba histolytica | cysteine protease, putative | 0.0565 | 0.2575 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0565 | 0.2575 | 0.2575 |
Leishmania major | cysteine peptidase A (CPA) | 0.0565 | 0.2575 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.039 | 0.0819 | 0.0819 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0565 | 0.2575 | 0.2575 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1304 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0496 | 0.188 | 0.7303 |
Brugia malayi | Cathepsin L-like precursor | 0.039 | 0.0819 | 0.0819 |
Loa Loa (eye worm) | ctsf protein | 0.0565 | 0.2575 | 0.1912 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0565 | 0.2575 | 0.2575 |
Onchocerca volvulus | Cathepsin F homolog | 0.0565 | 0.2575 | 1 |
Onchocerca volvulus | 0.0565 | 0.2575 | 1 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1304 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0565 | 0.2575 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1304 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.1304 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1304 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0565 | 0.2575 | 0.2575 |
Leishmania major | cathepsin L-like protease | 0.0565 | 0.2575 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0565 | 0.2575 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.039 | 0.0819 | 0.0819 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.039 | 0.0819 | 0.0819 |
Onchocerca volvulus | 0.0565 | 0.2575 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.039 | 0.0819 | 0.0819 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0565 | 0.2575 | 0.2575 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Leishmania major | cathepsin L-like protease | 0.0565 | 0.2575 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0565 | 0.2575 | 0.2575 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0565 | 0.2575 | 0.1912 |
Entamoeba histolytica | cysteine proteinase, putative | 0.039 | 0.0819 | 0.3182 |
Onchocerca volvulus | 0.0565 | 0.2575 | 1 | |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0565 | 0.2575 | 0.2575 |
Onchocerca volvulus | Cathepsin L homolog | 0.0565 | 0.2575 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0565 | 0.2575 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0565 | 0.2575 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0565 | 0.2575 | 0.2575 |
Leishmania major | cathepsin L-like protease | 0.0565 | 0.2575 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0496 | 0.188 | 0.5 |
Echinococcus multilocularis | cathepsin b | 0.1304 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0565 | 0.2575 | 0.2575 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0565 | 0.2575 | 1 |
Plasmodium vivax | vivapain-2 | 0.0565 | 0.2575 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0565 | 0.2575 | 0.1912 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0565 | 0.2575 | 0.2575 |
Brugia malayi | Cathepsin L-like precursor | 0.039 | 0.0819 | 0.0819 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0565 | 0.2575 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0565 | 0.2575 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0565 | 0.2575 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0565 | 0.2575 | 0.2575 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0565 | 0.2575 | 0.2575 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.039 | 0.0819 | 0.0819 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Leishmania major | cathepsin L-like protease | 0.0565 | 0.2575 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0565 | 0.2575 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.039 | 0.0819 | 0.3182 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0565 | 0.2575 | 0.2575 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0565 | 0.2575 | 0.1912 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0565 | 0.2575 | 1 |
Onchocerca volvulus | 0.0565 | 0.2575 | 1 | |
Onchocerca volvulus | 0.0565 | 0.2575 | 1 | |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0496 | 0.188 | 0.7303 |
Onchocerca volvulus | 0.0565 | 0.2575 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0565 | 0.2575 | 0.2575 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0565 | 0.2575 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0565 | 0.2575 | 0.2575 |
Loa Loa (eye worm) | cathepsin B | 0.0496 | 0.188 | 0.1156 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0565 | 0.2575 | 1 |
Leishmania major | cathepsin L-like protease | 0.0565 | 0.2575 | 1 |
Leishmania major | cathepsin L-like protease | 0.0565 | 0.2575 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0565 | 0.2575 | 0.2575 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.