Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.1963 | 0.5051 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0055 | 0.0789 | 0.063 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1307 | 0.1274 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0127 | 0.3159 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0149 | 0.3887 | 0.6229 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.1963 | 0.5051 |
Schistosoma mansoni | chromobox protein | 0.0074 | 0.1418 | 0.3292 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.005 | 0.0644 | 0.0608 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0149 | 0.3887 | 0.3864 |
Onchocerca volvulus | 0.0149 | 0.3887 | 0.5346 | |
Brugia malayi | tailless protein | 0.007 | 0.1307 | 0.2053 |
Onchocerca volvulus | 0.0251 | 0.7214 | 1 | |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0114 | 0.2742 | 0.8411 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.007 | 0.1307 | 0.1274 |
Brugia malayi | nuclear hormone receptor | 0.007 | 0.1307 | 0.2053 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0047 | 0.0534 | 0.0498 |
Brugia malayi | nuclear receptor RXR | 0.007 | 0.1307 | 0.2053 |
Brugia malayi | nuclear receptor NHR-88 | 0.0149 | 0.3887 | 0.6229 |
Echinococcus granulosus | chromobox protein 1 | 0.0074 | 0.1418 | 0.3649 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0149 | 0.3887 | 0.9181 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.06 | 0.0564 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.007 | 0.1307 | 0.3027 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0149 | 0.3887 | 0.6229 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0149 | 0.3887 | 1 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0114 | 0.2742 | 0.8411 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0149 | 0.3887 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0114 | 0.2742 | 0.8411 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0149 | 0.3887 | 0.9181 |
Mycobacterium tuberculosis | Probable reductase | 0.0114 | 0.2742 | 0.8411 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0992 | 0.2274 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0079 | 0.1583 | 0.3686 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0045 | 0.046 | 0.0553 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.3887 | 0.3864 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.3887 | 0.3864 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0149 | 0.3887 | 0.3864 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1307 | 0.1274 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.3887 | 0.3864 |
Trichomonas vaginalis | chromobox protein, putative | 0.0074 | 0.1418 | 0.1548 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 0.0992 | 0.1744 |
Echinococcus multilocularis | thymidylate synthase | 0.0115 | 0.2757 | 0.7063 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1583 | 0.1551 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1307 | 0.1274 |
Echinococcus granulosus | chromobox protein 1 | 0.0074 | 0.1418 | 0.3649 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0095 | 0.0092 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0055 | 0.0789 | 0.0402 |
Echinococcus granulosus | FTZ F1 alpha | 0.0149 | 0.3887 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.007 | 0.1307 | 0.3027 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1307 | 0.1274 |
Trichomonas vaginalis | chromobox protein, putative | 0.0045 | 0.046 | 0.015 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0149 | 0.3887 | 0.3864 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.007 | 0.1307 | 0.3027 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0149 | 0.3887 | 0.9181 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.007 | 0.1307 | 0.1274 |
Schistosoma mansoni | dihydrofolate reductase | 0.0047 | 0.0534 | 0.1182 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.3887 | 0.3864 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.007 | 0.1307 | 0.3363 |
Schistosoma mansoni | nuclear hormone receptor | 0.0149 | 0.3887 | 0.9181 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1307 | 0.1274 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.005 | 0.0642 | 0.0414 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0079 | 0.1583 | 0.2501 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.007 | 0.1307 | 0.3297 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1307 | 0.1274 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.007 | 0.1307 | 0.3297 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.007 | 0.1307 | 0.3027 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0992 | 0.2274 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0149 | 0.3887 | 1 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0055 | 0.0789 | 0.0971 |
Brugia malayi | ecdysone receptor | 0.007 | 0.1307 | 0.2053 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.005 | 0.0642 | 0.1653 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0149 | 0.3887 | 0.3864 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.007 | 0.1307 | 0.3363 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0162 | 0.4287 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.007 | 0.1307 | 0.3363 |
Brugia malayi | hypothetical protein | 0.0079 | 0.1583 | 0.2501 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.005 | 0.0642 | 0.157 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0074 | 0.1418 | 0.1386 |
Brugia malayi | Thioredoxin reductase | 0.005 | 0.0642 | 0.0978 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0115 | 0.2757 | 0.8466 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.007 | 0.1307 | 0.1738 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0079 | 0.1583 | 0.3686 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0149 | 0.3887 | 0.9181 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0091 | 0.1963 | 0.1933 |
Brugia malayi | conserved hypotetical protein | 0.007 | 0.1307 | 0.2053 |
Onchocerca volvulus | 0.007 | 0.1307 | 0.1738 | |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1307 | 0.1274 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0149 | 0.3887 | 0.3864 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.06 | 0.091 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0149 | 0.3887 | 0.5346 |
Mycobacterium ulcerans | thymidylate synthase | 0.0115 | 0.2757 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0114 | 0.2742 | 0.8411 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0992 | 0.206 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.007 | 0.1307 | 0.2053 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0149 | 0.3887 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.007 | 0.1307 | 0.2053 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0149 | 0.3887 | 0.6229 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0149 | 0.3887 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0149 | 0.3887 | 0.6229 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.007 | 0.1307 | 0.3297 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0149 | 0.3887 | 0.3864 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0149 | 0.3887 | 0.5346 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0095 | 0.0057 |
Echinococcus multilocularis | chromobox protein 1 | 0.0074 | 0.1418 | 0.3586 |
Trichomonas vaginalis | set domain proteins, putative | 0.0251 | 0.7214 | 1 |
Brugia malayi | Heterochromatin protein 1 | 0.0074 | 0.1418 | 0.2234 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0149 | 0.3887 | 0.6229 |
Schistosoma mansoni | nuclear hormone receptor | 0.007 | 0.1307 | 0.3027 |
Brugia malayi | hypothetical protein | 0.0129 | 0.3223 | 0.5154 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.007 | 0.1307 | 0.1738 |
Toxoplasma gondii | thioredoxin reductase | 0.005 | 0.0642 | 0.1422 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.007 | 0.1307 | 0.1274 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.1963 | 0.5002 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.06 | 0.0564 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.1963 | 0.4592 |
Brugia malayi | thymidylate synthase | 0.0115 | 0.2757 | 0.4399 |
Echinococcus granulosus | thymidylate synthase | 0.0115 | 0.2757 | 0.7092 |
Loa Loa (eye worm) | thymidylate synthase | 0.0115 | 0.2757 | 0.2729 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0065 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1583 | 0.1551 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0091 | 0.1963 | 0.3115 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0114 | 0.2742 | 0.8411 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.007 | 0.1307 | 0.2053 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0149 | 0.3887 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.3887 | 0.3864 |
Brugia malayi | hypothetical protein | 0.0079 | 0.1583 | 0.2501 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0162 | 0.4287 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.3887 | 0.3864 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1307 | 0.1274 |
Echinococcus granulosus | dihydrofolate reductase | 0.0047 | 0.0534 | 0.1373 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0149 | 0.3887 | 0.3864 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0149 | 0.3887 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1583 | 0.1551 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1583 | 0.1551 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0149 | 0.3887 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0149 | 0.3887 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.0038 | 0.0098 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0149 | 0.3887 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.007 | 0.1307 | 0.3297 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0149 | 0.3887 | 0.6229 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0079 | 0.1583 | 0.2501 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0047 | 0.0534 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.3887 | 0.3864 |
Schistosoma mansoni | thyroid hormone receptor | 0.0149 | 0.3887 | 0.9181 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0095 | 0.0136 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0127 | 0.3159 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0127 | 0.3159 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0149 | 0.3887 | 0.9181 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1307 | 0.1274 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0221 | 0.6218 | 0.6203 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0162 | 0.4287 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0149 | 0.3887 | 0.6229 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1307 | 0.1274 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0127 | 0.3159 | 1 |
Brugia malayi | chromobox protein homolog 3 | 0.0041 | 0.0357 | 0.0516 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0149 | 0.3887 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0149 | 0.3887 | 0.6229 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0149 | 0.3887 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0149 | 0.3887 | 0.3864 |
Brugia malayi | ecdysteroid receptor | 0.0149 | 0.3887 | 0.6229 |
Brugia malayi | nuclear receptor RXR | 0.0079 | 0.1583 | 0.2501 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.007 | 0.1307 | 0.3363 |
Schistosoma mansoni | thyroid hormone receptor | 0.0149 | 0.3887 | 0.9181 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0149 | 0.3887 | 0.9181 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0149 | 0.3887 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0357 | 0.0409 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.007 | 0.1307 | 0.3363 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.007 | 0.1307 | 0.2053 |
Trichomonas vaginalis | chromobox protein, putative | 0.0045 | 0.046 | 0.015 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0061 | 0.0992 | 0.0958 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0149 | 0.3887 | 0.6229 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0149 | 0.3887 | 1 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0047 | 0.0534 | 0.1288 |
Brugia malayi | glutathione reductase | 0.005 | 0.0642 | 0.0978 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.007 | 0.1307 | 0.3297 |
Plasmodium vivax | thioredoxin reductase, putative | 0.005 | 0.0642 | 0.1422 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0115 | 0.2757 | 0.6484 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.007 | 0.1307 | 0.2053 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.007 | 0.1307 | 0.3297 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0149 | 0.3887 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.007 | 0.1307 | 0.2053 |
Trichomonas vaginalis | chromobox protein, putative | 0.0074 | 0.1418 | 0.1548 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0149 | 0.3887 | 0.6229 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.3887 | 0.3864 |
Schistosoma mansoni | nuclear receptor | 0.007 | 0.1307 | 0.3027 |
Brugia malayi | hypothetical protein | 0.007 | 0.1307 | 0.2053 |
Loa Loa (eye worm) | thioredoxin reductase | 0.005 | 0.0642 | 0.0607 |
Brugia malayi | Dihydrofolate reductase | 0.0047 | 0.0534 | 0.0802 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.0992 | 0.2477 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0149 | 0.3887 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.1963 | 0.5002 |
Schistosoma mansoni | nuclear receptor | 0.007 | 0.1307 | 0.3027 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0079 | 0.1583 | 0.4015 |
Schistosoma mansoni | chromobox protein | 0.0074 | 0.1418 | 0.3292 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0044 | 0.0433 | 0.0943 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0149 | 0.3887 | 0.6229 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.1963 | 0.4592 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0115 | 0.2757 | 0.8466 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.0992 | 0.2244 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0061 | 0.0992 | 0.2551 |
Brugia malayi | dihydrofolate reductase family protein | 0.0047 | 0.0534 | 0.0802 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0162 | 0.4287 | 1 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0162 | 0.4287 | 1 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0162 | 0.4287 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0221 | 0.6218 | 1 |
Schistosoma mansoni | zinc finger protein | 0.007 | 0.1307 | 0.3027 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0149 | 0.3887 | 0.6229 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1307 | 0.1274 |
Onchocerca volvulus | 0.0115 | 0.2757 | 0.3765 | |
Brugia malayi | Nuclear hormone receptor E75 | 0.007 | 0.1307 | 0.2053 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0149 | 0.3887 | 0.5346 |
Brugia malayi | nuclear receptor NHR-67 | 0.007 | 0.1307 | 0.2053 |
Brugia malayi | Cytochrome P450 family protein | 0.005 | 0.0644 | 0.098 |
Schistosoma mansoni | coup transcription factor | 0.0149 | 0.3887 | 0.9181 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0357 | 0.032 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0149 | 0.3887 | 0.6229 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0149 | 0.3887 | 0.6229 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0114 | 0.2742 | 0.8411 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1583 | 0.1551 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0149 | 0.3887 | 0.6229 |
Loa Loa (eye worm) | DR-78 | 0.007 | 0.1307 | 0.1274 |
Onchocerca volvulus | 0.007 | 0.1307 | 0.1738 | |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0149 | 0.3887 | 0.6229 |
Onchocerca volvulus | 0.0044 | 0.0433 | 0.0516 | |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0992 | 0.206 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0079 | 0.1583 | 0.4073 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0149 | 0.3887 | 0.9181 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0149 | 0.3887 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0079 | 0.1583 | 0.1551 |
Echinococcus multilocularis | chromobox protein 1 | 0.0074 | 0.1418 | 0.3586 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0149 | 0.3887 | 0.9181 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1307 | 0.1274 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.0796 | 0.1808 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0149 | 0.3887 | 0.9181 |
Plasmodium vivax | glutathione reductase, putative | 0.005 | 0.0642 | 0.1422 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0992 | 0.206 |
Brugia malayi | steroid hormone receptor | 0.0149 | 0.3887 | 0.6229 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.007 | 0.1307 | 0.3363 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.06 | 0.091 |
Loa Loa (eye worm) | glutathione reductase | 0.005 | 0.0642 | 0.0607 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1307 | 0.1274 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.1963 | 0.4592 |
Brugia malayi | nuclear hormone receptor | 0.0149 | 0.3887 | 0.6229 |
Brugia malayi | hypothetical protein | 0.0055 | 0.0789 | 0.1215 |
Brugia malayi | hypothetical protein | 0.007 | 0.1307 | 0.2053 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 51.62 % | Inhibition of oleate production in Mycobacterium bovis BCG | ChEMBL. | 16875817 |
Inhibition (functional) | = 51.62 % | Inhibition of oleate production in Mycobacterium bovis BCG | ChEMBL. | 16875817 |
MIC99 (functional) | Antibacterial activity against Mycobacterium tuberculosis H37Rv | ChEMBL. | 16875817 | |
MIC99 (functional) | 0 | Antibacterial activity against Mycobacterium tuberculosis H37Rv | ChEMBL. | 16875817 |
MIC99 (functional) | = 0.9 ug ml-1 | Antibacterial activity against Mycobacterium bovis BCG | ChEMBL. | 16875817 |
MIC99 (functional) | = 0.9 ug ml-1 | Antibacterial activity against Mycobacterium bovis BCG | ChEMBL. | 16875817 |
Selectivity index (functional) | 0 | Selectivity index, IC50 against Vero cells/MIC against Mycobacterium | ChEMBL. | 16875817 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.