Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.0306 | 0.5248 | 0.3264 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase abl1 | 0.0306 | 0.5248 | 0.5062 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus granulosus | suppressor of cytokine signaling 7 | 0.0306 | 0.5248 | 0.4527 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0512 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0512 | 1 | 1 |
Echinococcus granulosus | expressed conserved protein | 0.0306 | 0.5248 | 0.4527 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus granulosus | SH2 domain containing adapter protein F | 0.0306 | 0.5248 | 0.4527 |
Schistosoma mansoni | signal transduction protein lnk-related | 0.0306 | 0.5248 | 0.5062 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Brugia malayi | SH2 domain containing protein | 0.0306 | 0.5248 | 0.3264 |
Loa Loa (eye worm) | hypothetical protein | 0.0306 | 0.5248 | 0.3264 |
Brugia malayi | SH2 domain containing protein | 0.0306 | 0.5248 | 0.3264 |
Toxoplasma gondii | Tyrosine kinase-like (TKL) protein | 0.0206 | 0.2946 | 0.5 |
Schistosoma mansoni | protein kinase | 0.0206 | 0.2946 | 0.2669 |
Brugia malayi | SH2 domain containing protein | 0.0306 | 0.5248 | 0.3264 |
Schistosoma mansoni | src-type protein tyrosine kinase-related | 0.0206 | 0.2946 | 0.2669 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0512 | 1 | 1 |
Trichomonas vaginalis | br serine/threonine-protein kinase, putative | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | protein tyrosine kinase | 0.0206 | 0.2946 | 0.1876 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.0306 | 0.5248 | 0.5062 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0512 | 1 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0512 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0306 | 0.5248 | 0.3264 |
Trypanosoma brucei | Pseudokinase, putative | 0.0206 | 0.2946 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase transmembrane receptor | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | tyrosine protein kinase csk | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0306 | 0.5248 | 0.4527 |
Schistosoma mansoni | adapter molecule crk | 0.0306 | 0.5248 | 0.5062 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | SH2 domain containing adapter protein F | 0.0306 | 0.5248 | 0.4527 |
Echinococcus granulosus | guanine nucleotide exchange factor VAV2 | 0.0306 | 0.5248 | 0.4527 |
Echinococcus multilocularis | receptor type guanylyl cyclase | 0.0206 | 0.2946 | 0.1876 |
Echinococcus granulosus | macrophage colony stimulating factor 1 receptor | 0.0206 | 0.2946 | 0.1876 |
Schistosoma mansoni | tensin | 0.0306 | 0.5248 | 0.5062 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0512 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0512 | 1 | 1 |
Brugia malayi | SRC-1 | 0.0512 | 1 | 1 |
Echinococcus multilocularis | basic fibroblast growth factor receptor 1 A | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | tensin | 0.0306 | 0.5248 | 0.4527 |
Echinococcus granulosus | SH2 motif | 0.0306 | 0.5248 | 0.4527 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Plasmodium vivax | tyrosine kinase-like protein, putative | 0.0206 | 0.2946 | 0.5 |
Trypanosoma brucei | STE/STE11 serine/threonine-protein kinase, putative | 0.0206 | 0.2946 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase transmembrane receptor | 0.0206 | 0.2946 | 0.1876 |
Trichomonas vaginalis | serine/threonine-protein kinase wnk, putative | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus granulosus | atrial natriuretic peptide receptor 1 | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | tyrosine protein kinase transmembrane receptor | 0.0206 | 0.2946 | 0.1876 |
Schistosoma mansoni | hypothetical protein | 0.0306 | 0.5248 | 0.5062 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0512 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0306 | 0.5248 | 0.4527 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0512 | 1 | 1 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0306 | 0.5248 | 0.3264 |
Schistosoma mansoni | protein kinase | 0.0206 | 0.2946 | 0.2669 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0206 | 0.2946 | 1 |
Leishmania major | protein kinase, putative | 0.0206 | 0.2946 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase csk | 0.0206 | 0.2946 | 0.1876 |
Brugia malayi | tRNA modification GTPase TrmE family protein | 0.0306 | 0.5248 | 0.3264 |
Schistosoma mansoni | protein kinase | 0.0206 | 0.2946 | 0.2669 |
Schistosoma mansoni | ephrin receptor | 0.0206 | 0.2946 | 0.2669 |
Loa Loa (eye worm) | cytokine inducible SH2-containing protein 5 | 0.0306 | 0.5248 | 0.3264 |
Brugia malayi | SH2 domain containing protein | 0.0306 | 0.5248 | 0.3264 |
Echinococcus granulosus | SHC transforming protein 3 | 0.0306 | 0.5248 | 0.4527 |
Toxoplasma gondii | Tyrosine kinase-like (TKL) protein | 0.0206 | 0.2946 | 0.5 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0512 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0512 | 1 | 1 |
Echinococcus multilocularis | retinal guanylyl cyclase 2 | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | integrin linked protein kinase | 0.0206 | 0.2946 | 0.1876 |
Echinococcus granulosus | fibroblast growth factor receptor 4 | 0.0206 | 0.2946 | 0.1876 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0512 | 1 | 1 |
Echinococcus multilocularis | NCK adaptor protein | 0.0306 | 0.5248 | 0.4527 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Brugia malayi | Protein kinase domain containing protein | 0.0512 | 1 | 1 |
Schistosoma mansoni | tensin | 0.0306 | 0.5248 | 0.5062 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0512 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase pr2 | 0.0206 | 0.2946 | 0.1876 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0306 | 0.5248 | 0.4527 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Schistosoma mansoni | tensin-related | 0.0306 | 0.5248 | 0.5062 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.0306 | 0.5248 | 0.3264 |
Onchocerca volvulus | Suppressor of cytokine signaling at 36E homolog | 0.0306 | 0.5248 | 0.3264 |
Echinococcus multilocularis | SH2 motif | 0.0306 | 0.5248 | 0.4527 |
Echinococcus granulosus | natriuretic peptide receptor 1 | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.0512 | 1 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | tyrosine protein kinase pr2 | 0.0206 | 0.2946 | 0.1876 |
Loa Loa (eye worm) | RhoGAP domain-containing protein | 0.0306 | 0.5248 | 0.3264 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Echinococcus multilocularis | tyrosine protein kinase HCK | 0.0206 | 0.2946 | 0.1876 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0306 | 0.5248 | 0.3264 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0512 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0306 | 0.5248 | 0.3264 |
Echinococcus multilocularis | tyrosine protein kinase Fes:Fps | 0.0206 | 0.2946 | 0.1876 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Brugia malayi | Variant SH3 domain containing protein | 0.0306 | 0.5248 | 0.3264 |
Schistosoma mansoni | hypothetical protein | 0.0306 | 0.5248 | 0.5062 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | ephrin type A receptor 4 A | 0.0206 | 0.2946 | 0.1876 |
Schistosoma mansoni | protein kinase | 0.0206 | 0.2946 | 0.2669 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0306 | 0.5248 | 0.3264 |
Schistosoma mansoni | shc transforming protein | 0.0306 | 0.5248 | 0.5062 |
Loa Loa (eye worm) | hypothetical protein | 0.0306 | 0.5248 | 0.3264 |
Echinococcus multilocularis | guanine nucleotide exchange factor VAV2 | 0.0306 | 0.5248 | 0.4527 |
Onchocerca volvulus | 0.0306 | 0.5248 | 0.3264 | |
Plasmodium falciparum | tyrosine kinase-like protein | 0.0206 | 0.2946 | 0.5 |
Giardia lamblia | Kinase, NEK | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0512 | 1 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.0206 | 0.2946 | 0.5 |
Echinococcus granulosus | c src tyrosine kinase | 0.0512 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase HCK | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | tyrosine kinase | 0.0512 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0512 | 1 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus granulosus | suppressor of cytokine signaling 6 | 0.0306 | 0.5248 | 0.4527 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | STE family protein kinase | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0206 | 0.2946 | 0.1876 |
Trypanosoma brucei | Flagellum attachment zone protein 20 | 0.0206 | 0.2946 | 0.5 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Brugia malayi | SH2 domain containing protein | 0.0512 | 1 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0306 | 0.5248 | 0.4527 |
Echinococcus multilocularis | phosphatidylinositol 3 kinase regulatory subunit | 0.0306 | 0.5248 | 0.4527 |
Schistosoma mansoni | tyrosine protein kinase fes (fps) (ptk group IV) | 0.0206 | 0.2946 | 0.2669 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus granulosus | tyrosine protein kinase | 0.0206 | 0.2946 | 0.1876 |
Leishmania major | protein kinase, putative | 0.0206 | 0.2946 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Schistosoma mansoni | tyrosine-protein kinase fps85d | 0.0206 | 0.2946 | 0.2669 |
Schistosoma mansoni | ephrin receptor | 0.0206 | 0.2946 | 0.2669 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Echinococcus granulosus | tyrosine protein kinase shark | 0.0512 | 1 | 1 |
Brugia malayi | protein-tyrosine kinase | 0.0512 | 1 | 1 |
Echinococcus multilocularis | retinal guanylyl cyclase 2 | 0.0206 | 0.2946 | 0.1876 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Onchocerca volvulus | 0.0512 | 1 | 1 | |
Schistosoma mansoni | protein kinase | 0.0206 | 0.2946 | 0.2669 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus granulosus | tyrosine kinase | 0.0512 | 1 | 1 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0512 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0206 | 0.2946 | 0.2669 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0512 | 1 | 1 |
Onchocerca volvulus | 0.0512 | 1 | 1 | |
Brugia malayi | Sex muscle abnormal protein 5 | 0.0306 | 0.5248 | 0.3264 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | protein kinase | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0512 | 1 | 1 |
Loa Loa (eye worm) | STAT protein | 0.0306 | 0.5248 | 0.3264 |
Echinococcus granulosus | signal transduction protein lnk realted | 0.0306 | 0.5248 | 0.4527 |
Echinococcus multilocularis | protein kinase | 0.0206 | 0.2946 | 0.1876 |
Loa Loa (eye worm) | TK protein kinase | 0.0512 | 1 | 1 |
Entamoeba histolytica | SH2 domain containing protein | 0.0306 | 0.5248 | 0.3264 |
Schistosoma mansoni | tensin | 0.0306 | 0.5248 | 0.5062 |
Schistosoma mansoni | tyrosine protein kinase | 0.0206 | 0.2946 | 0.2669 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0512 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0306 | 0.5248 | 0.3264 |
Echinococcus granulosus | tyrosine protein kinase csk | 0.0206 | 0.2946 | 0.1876 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.0306 | 0.5248 | 0.3264 |
Schistosoma mansoni | SH2A | 0.0306 | 0.5248 | 0.5062 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Schistosoma mansoni | protein kinase | 0.0206 | 0.2946 | 0.2669 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0512 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Brugia malayi | SH2 domain containing protein | 0.0306 | 0.5248 | 0.3264 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0206 | 0.2946 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0512 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0206 | 0.2946 | 0.2669 |
Echinococcus multilocularis | FL cytokine receptor | 0.0206 | 0.2946 | 0.1876 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0512 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Srms | 0.0512 | 1 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | suppressor of cytokine signaling 7 | 0.0306 | 0.5248 | 0.4527 |
Echinococcus granulosus | integrin linked protein kinase | 0.0206 | 0.2946 | 0.1876 |
Trichomonas vaginalis | serine-threonine protein kinase, putative | 0.0206 | 0.2946 | 1 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0512 | 1 | 1 |
Echinococcus granulosus | protein tyrosine kinase | 0.0206 | 0.2946 | 0.1876 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus granulosus | phosphatidylinositol 3 kinase regulatory subunit | 0.0306 | 0.5248 | 0.4527 |
Echinococcus granulosus | kinase suppressor of Ras 1 | 0.0206 | 0.2946 | 0.1876 |
Toxoplasma gondii | STE kinase | 0.0206 | 0.2946 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0512 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0512 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Brugia malayi | Tensin | 0.0306 | 0.5248 | 0.3264 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Brugia malayi | SH2 domain containing protein | 0.0306 | 0.5248 | 0.3264 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Schistosoma mansoni | protein kinase | 0.0206 | 0.2946 | 0.2669 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0206 | 0.2946 | 0.1876 |
Schistosoma mansoni | tyrosine kinase | 0.0512 | 1 | 1 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.0306 | 0.5248 | 0.4527 |
Schistosoma mansoni | hypothetical protein | 0.0206 | 0.2946 | 0.2669 |
Echinococcus multilocularis | activin receptor type | 0.0206 | 0.2946 | 0.1876 |
Brugia malayi | hypothetical protein | 0.0512 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0512 | 1 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0512 | 1 | 1 |
Echinococcus multilocularis | fibroblast growth factor receptor 4 | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | 0.0306 | 0.5248 | 0.4527 | |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus granulosus | retinal guanylyl cyclase 2 | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | retinal guanylyl cyclase 2 | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0512 | 1 | 1 |
Plasmodium falciparum | protein kinase, putative | 0.0206 | 0.2946 | 0.5 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0206 | 0.2946 | 0.1876 |
Brugia malayi | hypothetical protein | 0.0306 | 0.5248 | 0.3264 |
Echinococcus granulosus | SH2 domain containing protein 7 | 0.0306 | 0.5248 | 0.4527 |
Echinococcus granulosus | protein kinase | 0.0206 | 0.2946 | 0.1876 |
Schistosoma mansoni | protein tyrosine phosphatase n11 (shp2) | 0.0306 | 0.5248 | 0.5062 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Onchocerca volvulus | 0.0306 | 0.5248 | 0.3264 | |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | SH2 motif | 0.0306 | 0.5248 | 0.4527 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | tyrosine protein kinase csk | 0.0206 | 0.2946 | 0.1876 |
Onchocerca volvulus | 0.0306 | 0.5248 | 0.3264 | |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0512 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0512 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | macrophage colony stimulating factor 1 receptor | 0.0206 | 0.2946 | 0.1876 |
Brugia malayi | Tyrosine-protein kinase abl-1 | 0.0512 | 1 | 1 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0206 | 0.2946 | 0.2669 |
Echinococcus granulosus | tyrosine kinase | 0.0512 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.0512 | 1 | 1 |
Echinococcus granulosus | tyrosine protein kinase Fes:Fps | 0.0206 | 0.2946 | 0.1876 |
Brugia malayi | cytokine inducible SH2-containing protein 5 | 0.0306 | 0.5248 | 0.3264 |
Echinococcus multilocularis | tensin | 0.0306 | 0.5248 | 0.4527 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Onchocerca volvulus | 0.0512 | 1 | 1 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0512 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0306 | 0.5248 | 0.3264 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0306 | 0.5248 | 0.3264 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Loa Loa (eye worm) | hypothetical protein | 0.0306 | 0.5248 | 0.3264 |
Schistosoma mansoni | tyrosine kinase | 0.0512 | 1 | 1 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0512 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fps85D | 0.0512 | 1 | 1 |
Brugia malayi | Variant SH3 domain containing protein | 0.0306 | 0.5248 | 0.3264 |
Brugia malayi | Variant SH3 domain containing protein | 0.0306 | 0.5248 | 0.3264 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Echinococcus multilocularis | tyrosine kinase | 0.0206 | 0.2946 | 0.1876 |
Schistosoma mansoni | protein tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Brugia malayi | RhoGAP domain containing protein | 0.0306 | 0.5248 | 0.3264 |
Onchocerca volvulus | 0.0306 | 0.5248 | 0.3264 | |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Trichomonas vaginalis | TK family protein kinase | 0.0206 | 0.2946 | 1 |
Schistosoma mansoni | serine/threonine RGC | 0.0206 | 0.2946 | 0.2669 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Echinococcus granulosus | activated cdc42 kinase 1 | 0.0206 | 0.2946 | 0.1876 |
Schistosoma mansoni | protein kinase | 0.0206 | 0.2946 | 0.2669 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0512 | 1 | 1 |
Schistosoma mansoni | protein kinase | 0.0206 | 0.2946 | 0.2669 |
Echinococcus granulosus | raf serine:threonine protein kinase | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | suppressor of cytokine signaling 7 | 0.0306 | 0.5248 | 0.4527 |
Toxoplasma gondii | calcium dependent protein kinase CDPK8 | 0.0206 | 0.2946 | 0.5 |
Toxoplasma gondii | protein kinase domain-containing protein | 0.0206 | 0.2946 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0512 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0306 | 0.5248 | 0.3264 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.0206 | 0.2946 | 0.1876 |
Echinococcus granulosus | insulin receptor | 0.0206 | 0.2946 | 0.1876 |
Trichomonas vaginalis | protein kinase atn1, putative | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.0512 | 1 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Plasmodium vivax | protein kinase, putative | 0.0206 | 0.2946 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0206 | 0.2946 | 1 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0512 | 1 | 1 |
Echinococcus granulosus | mitogen-activated protein kinase kinase kinase 9 | 0.0206 | 0.2946 | 0.1876 |
Loa Loa (eye worm) | SRC-1 | 0.0512 | 1 | 1 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0206 | 0.2946 | 0.1876 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.0306 | 0.5248 | 0.4527 |
Plasmodium falciparum | protein kinase, putative | 0.0206 | 0.2946 | 0.5 |
Onchocerca volvulus | 0.0512 | 1 | 1 | |
Giardia lamblia | Kinase | 0.0206 | 0.2946 | 1 |
Schistosoma mansoni | suppressor of cytokine signaling | 0.0306 | 0.5248 | 0.5062 |
Schistosoma mansoni | tyrosine protein kinase fes (fps) (ptk group IV) | 0.0206 | 0.2946 | 0.2669 |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.0306 | 0.5248 | 0.5062 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Plasmodium falciparum | protein kinase, putative | 0.0206 | 0.2946 | 0.5 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Onchocerca volvulus | 0.0512 | 1 | 1 | |
Giardia lamblia | Kinase, NEK | 0.0206 | 0.2946 | 1 |
Brugia malayi | SH2 domain containing protein | 0.0306 | 0.5248 | 0.3264 |
Brugia malayi | Protein kinase domain containing protein | 0.0512 | 1 | 1 |
Echinococcus multilocularis | SH2 motif | 0.0306 | 0.5248 | 0.4527 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.0306 | 0.5248 | 0.3264 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0206 | 0.2946 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Giardia lamblia | Protein 21.1 | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | N chimaerin | 0.0306 | 0.5248 | 0.4527 |
Trypanosoma brucei | AGC/RSK family serine/threonine kinase, putative | 0.0206 | 0.2946 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase csk | 0.0206 | 0.2946 | 0.1876 |
Loa Loa (eye worm) | hypothetical protein | 0.0306 | 0.5248 | 0.3264 |
Schistosoma mansoni | tyrosine-protein kinase zap-70 | 0.0306 | 0.5248 | 0.5062 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0306 | 0.5248 | 0.3264 |
Echinococcus granulosus | 3'partial|retinal guanylyl cyclase 2 | 0.0206 | 0.2946 | 0.1876 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Onchocerca volvulus | Suppressor of cytokine signaling 7 homolog | 0.0306 | 0.5248 | 0.3264 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Echinococcus granulosus | mitogen activated protein kinase kinase kinase | 0.0206 | 0.2946 | 0.1876 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0512 | 1 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus granulosus | receptor type guanylyl cyclase | 0.0206 | 0.2946 | 0.1876 |
Echinococcus granulosus | tyrosine kinase | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | c src tyrosine kinase | 0.0512 | 1 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Onchocerca volvulus | 0.0306 | 0.5248 | 0.3264 | |
Schistosoma mansoni | suppressor of cytokine signaling | 0.0306 | 0.5248 | 0.5062 |
Trichomonas vaginalis | ankyrin repeat-containing protein, putative | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | atrial natriuretic peptide receptor 1 | 0.0206 | 0.2946 | 0.1876 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0306 | 0.5248 | 0.5062 |
Onchocerca volvulus | 0.0306 | 0.5248 | 0.3264 | |
Schistosoma mansoni | tyrosine-protein kinase fps85d | 0.0206 | 0.2946 | 0.2669 |
Loa Loa (eye worm) | hypothetical protein | 0.0306 | 0.5248 | 0.3264 |
Echinococcus granulosus | retinal guanylyl cyclase 2 | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | insulin receptor | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | kinase suppressor of Ras 1 | 0.0206 | 0.2946 | 0.1876 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0512 | 1 | 1 |
Toxoplasma gondii | protein kinase | 0.0206 | 0.2946 | 0.5 |
Echinococcus granulosus | activated cdc42 kinase 1 | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | suppressor of cytokine signaling 6 | 0.0306 | 0.5248 | 0.4527 |
Echinococcus granulosus | retinal guanylyl cyclase 2 | 0.0206 | 0.2946 | 0.1876 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Plasmodium falciparum | tyrosine kinase-like protein | 0.0206 | 0.2946 | 0.5 |
Echinococcus multilocularis | dual specificity testis specific protein kinase | 0.0206 | 0.2946 | 0.1876 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0512 | 1 | 1 |
Schistosoma mansoni | protein kinase | 0.0206 | 0.2946 | 0.2669 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0306 | 0.5248 | 0.4527 |
Schistosoma mansoni | nck2/grb4 | 0.0306 | 0.5248 | 0.5062 |
Echinococcus granulosus | tyrosine protein kinase transmembrane receptor | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | SH2 domain containing protein 7 | 0.0306 | 0.5248 | 0.4527 |
Echinococcus multilocularis | signal transduction protein lnk realted | 0.0306 | 0.5248 | 0.4527 |
Echinococcus multilocularis | activated cdc42 kinase 1 | 0.0206 | 0.2946 | 0.1876 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.0206 | 0.2946 | 0.1876 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Echinococcus granulosus | tyrosine protein kinase csk | 0.0206 | 0.2946 | 0.1876 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Echinococcus granulosus | NCK adaptor protein | 0.0306 | 0.5248 | 0.4527 |
Loa Loa (eye worm) | hypothetical protein | 0.0306 | 0.5248 | 0.3264 |
Echinococcus multilocularis | protein KINase family member (kin 25) | 0.0206 | 0.2946 | 0.1876 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0206 | 0.2946 | 0.5 |
Schistosoma mansoni | vav2 | 0.0306 | 0.5248 | 0.5062 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | raf serine:threonine protein kinase | 0.0206 | 0.2946 | 0.1876 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0306 | 0.5248 | 0.5062 |
Echinococcus multilocularis | heat shock protein 70 | 0.0206 | 0.2946 | 0.1876 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0206 | 0.2946 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0306 | 0.5248 | 0.3264 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | SHC transforming protein 3 | 0.0306 | 0.5248 | 0.4527 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Brugia malayi | Variant SH3 domain containing protein | 0.0306 | 0.5248 | 0.3264 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0206 | 0.2946 | 0.2669 |
Echinococcus multilocularis | transfer RNA-Thr | 0.0206 | 0.2946 | 0.1876 |
Schistosoma mansoni | lipoxygenase | 0.0136 | 0.1317 | 0.0977 |
Brugia malayi | SH2 domain containing protein | 0.0512 | 1 | 1 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0306 | 0.5248 | 0.4527 |
Plasmodium vivax | tyrosine kinase-like protein, putative | 0.0206 | 0.2946 | 0.5 |
Echinococcus granulosus | tensin | 0.0306 | 0.5248 | 0.4527 |
Echinococcus multilocularis | tyrosine protein kinase csk | 0.0206 | 0.2946 | 0.1876 |
Trichomonas vaginalis | protein tyrosine kinase, putative | 0.0206 | 0.2946 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0512 | 1 | 1 |
Onchocerca volvulus | 0.0512 | 1 | 1 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0206 | 0.2946 | 0.2669 |
Schistosoma mansoni | tyrosine kinase | 0.0512 | 1 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0512 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0306 | 0.5248 | 0.3264 |
Schistosoma mansoni | GTPase activating protein | 0.0306 | 0.5248 | 0.5062 |
Echinococcus granulosus | hypothetical protein | 0.0306 | 0.5248 | 0.4527 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus granulosus | activin receptor type | 0.0206 | 0.2946 | 0.1876 |
Echinococcus granulosus | tyrosine protein kinase Fps85D | 0.0512 | 1 | 1 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0306 | 0.5248 | 0.3264 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0512 | 1 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0206 | 0.2946 | 0.1876 |
Trypanosoma cruzi | protein kinase, putative | 0.0206 | 0.2946 | 0.5 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Trichomonas vaginalis | TKL family protein kinase | 0.0206 | 0.2946 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0306 | 0.5248 | 0.3264 |
Echinococcus multilocularis | mitogen activated protein kinase kinase kinase | 0.0206 | 0.2946 | 0.1876 |
Schistosoma mansoni | protein kinase | 0.0206 | 0.2946 | 0.2669 |
Schistosoma mansoni | tyrosine kinase | 0.0206 | 0.2946 | 0.2669 |
Brugia malayi | Protein kinase domain containing protein | 0.0512 | 1 | 1 |
Echinococcus granulosus | N chimaerin | 0.0306 | 0.5248 | 0.4527 |
Echinococcus granulosus | ephrin type A receptor 4 A | 0.0206 | 0.2946 | 0.1876 |
Echinococcus granulosus | SH2 motif | 0.0306 | 0.5248 | 0.4527 |
Schistosoma mansoni | tensin-related | 0.0306 | 0.5248 | 0.5062 |
Echinococcus granulosus | basic fibroblast growth factor receptor 1 A | 0.0206 | 0.2946 | 0.1876 |
Brugia malayi | STAT protein, DNA binding domain containing protein | 0.0306 | 0.5248 | 0.3264 |
Echinococcus granulosus | tensin C1 domain containing phosphatase | 0.0306 | 0.5248 | 0.4527 |
Echinococcus multilocularis | natriuretic peptide receptor 1 | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.0512 | 1 | 1 |
Echinococcus granulosus | dual specificity testis-specific protein kinase | 0.0206 | 0.2946 | 0.1876 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0206 | 0.2946 | 0.1876 |
Trypanosoma cruzi | protein kinase, putative | 0.0206 | 0.2946 | 0.5 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0306 | 0.5248 | 0.3264 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | = 226.7 uM | In vitro reversal activity versus ~90% block by rocuronium in isolated mouse hemidiaphragm,expressed as effective conc. | ChEMBL. | 11960492 |
Max reversal (functional) | = 42.3 % | In vitro reversal activity versus ~90% block by rocuronium in isolated mouse hemidiaphragm,expressed as % of maximum reversal at 216 uM conc. | ChEMBL. | 11960492 |
NT (functional) | 0 | In vivo reversal activity versus ~90% block by rocuronium in guinea pig; not tested | ChEMBL. | 11960492 |
NT (functional) | 0 | In vivo reversal activity versus ~90% block by rocuronium in guinea pig, expressed as % of maximum reversal; not tested | ChEMBL. | 11960492 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.