Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | membrane associated guanylate kinase, WW and PDZ domain containing 3 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | phosphoglucomutase | 0.011 | 0.2404 | 0.2404 |
Echinococcus granulosus | 3'partial|membrane associated guanylate kinase ww and pdz | 0.003 | 0.0397 | 0.165 |
Trypanosoma brucei | ingi protein (ORF1) | 0.012 | 0.2639 | 0.0309 |
Schistosoma mansoni | phosphoglucomutase | 0.011 | 0.2404 | 0.2404 |
Trypanosoma brucei | retrotransposon hot spot protein 4 (RHS4), interrupted | 0.012 | 0.2639 | 0.0309 |
Echinococcus multilocularis | ribonuclease H1 | 0.011 | 0.2404 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0397 | 0.957 |
Echinococcus granulosus | membrane associated guanylate kinase, WW and PDZ | 0.003 | 0.0397 | 0.165 |
Brugia malayi | PDZ domain containing protein | 0.0031 | 0.0414 | 0.1724 |
Trypanosoma brucei | unspecified product | 0.012 | 0.2639 | 0.0309 |
Echinococcus multilocularis | membrane associated guanylate kinase, WW and PDZ | 0.003 | 0.0397 | 0.165 |
Trichomonas vaginalis | ribonuclease H1, putative | 0.011 | 0.2404 | 0.5 |
Leishmania major | ribonuclease H1, putative | 0.011 | 0.2404 | 0.5 |
Onchocerca volvulus | Ribonuclease H1 homolog | 0.011 | 0.2404 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.012 | 0.2639 | 0.0309 |
Trypanosoma brucei | ingi protein (ORF1) | 0.012 | 0.2639 | 0.0309 |
Brugia malayi | RNase H family protein | 0.011 | 0.2404 | 1 |
Toxoplasma gondii | ribonuclease HI protein | 0.011 | 0.2404 | 0.5 |
Echinococcus granulosus | membrane associated guanylate kinase ww and pdz | 0.003 | 0.0397 | 0.165 |
Schistosoma mansoni | phosphoglucomutase | 0.011 | 0.2404 | 0.2404 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0414 | 1 |
Echinococcus granulosus | membrane associated guanylate kinase ww and pdz | 0.0042 | 0.0693 | 0.2884 |
Giardia lamblia | Ribonuclease H | 0.011 | 0.2404 | 0.5 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.011 | 0.2404 | 0.5 |
Brugia malayi | RNase H family protein | 0.011 | 0.2404 | 1 |
Echinococcus multilocularis | membrane associated guanylate kinase ww and pdz | 0.003 | 0.0397 | 0.165 |
Echinococcus granulosus | ribonuclease H1 | 0.011 | 0.2404 | 1 |
Schistosoma mansoni | membrane associated guanylate kinase inverted related | 0.0042 | 0.0693 | 0.0693 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.011 | 0.2404 | 0.5 |
Brugia malayi | RNase H family protein | 0.011 | 0.2404 | 1 |
Trypanosoma brucei | RNA helicase, putative | 0.0414 | 1 | 1 |
Treponema pallidum | ribonuclease H (rnhA) | 0.011 | 0.2404 | 0.5 |
Schistosoma mansoni | membrane associated guanylate kinase inverted related | 0.003 | 0.0397 | 0.0397 |
Wolbachia endosymbiont of Brugia malayi | ribonuclease HI | 0.011 | 0.2404 | 0.5 |
Echinococcus multilocularis | 0.0042 | 0.0693 | 0.2884 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.