Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0051 | 0.2513 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0021 | 0.0274 | 0.0274 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0053 | 0.2688 | 0.2688 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 1 | 1 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0153 | 1 | 1 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0029 | 0.086 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | G protein-coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0153 | 1 | 1 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | fmrfamide receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0021 | 0.0274 | 0.1018 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | neuropeptide F receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | fibroinase | 0.0029 | 0.086 | 0.0722 |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Giardia lamblia | Cathepsin B precursor | 0.0053 | 0.2688 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | G-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0149 | 0.0149 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0021 | 0.0274 | 0.0274 |
Echinococcus multilocularis | allatostatin A receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0029 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | somatostatin receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Onchocerca volvulus | Cathepsin L homolog | 0.0029 | 0.086 | 0.2619 |
Plasmodium vivax | vivapain-2 | 0.0029 | 0.086 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0153 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0149 | 0.0149 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0051 | 0.2513 | 0.24 |
Trypanosoma brucei | RNA helicase, putative | 0.0138 | 0.8886 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Dopamine receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0053 | 0.2688 | 1 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Brugia malayi | sulfakinin receptor protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Brugia malayi | Cathepsin L-like precursor | 0.0021 | 0.0274 | 0.0274 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0051 | 0.2513 | 0.2513 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Brugia malayi | RE15519p | 0.0051 | 0.2513 | 0.2513 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0149 | 0.1732 |
Echinococcus multilocularis | serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0029 | 0.086 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | GnHR receptor homolog | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0029 | 0.086 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0053 | 0.2688 | 0.3024 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus granulosus | orexin receptor type 2 | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0274 | 0.0127 |
Brugia malayi | Dopamine receptor protein 1 | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0029 | 0.086 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0153 | 1 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | g-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | ORL1-like opioid receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | neuropeptide F receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | cathepsin b | 0.0153 | 1 | 1 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus granulosus | cathepsin b | 0.0153 | 1 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0149 | 0.1732 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | opsin-like receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus multilocularis | cysteine protease | 0.0029 | 0.086 | 0.086 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0149 | 0.0149 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | somatostatin receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | Cathepsin L-like precursor | 0.0021 | 0.0274 | 0.0274 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Giardia lamblia | Cathepsin B precursor | 0.0053 | 0.2688 | 1 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0149 | 0.5 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0149 | 0.0554 |
Echinococcus multilocularis | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | cathepsin l1 | 0.0029 | 0.086 | 0.086 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | sex peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | larval opioid receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Toxoplasma gondii | cathepsin CPL | 0.0029 | 0.086 | 0.2802 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0053 | 0.2688 | 1 |
Echinococcus granulosus | serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0149 | 0.0149 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | biogenic amine receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | ctsf protein | 0.0029 | 0.086 | 0.0722 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | Cathepsin F homolog | 0.0029 | 0.086 | 0.2619 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Schistosoma mansoni | opsin-like receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0274 | 0.0127 |
Echinococcus granulosus | cathepsin b | 0.0153 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0029 | 0.086 | 0.0722 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0029 | 0.086 | 1 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0149 | 0.0168 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0029 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0021 | 0.0274 | 0.1018 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | adenoreceptor | 0.0051 | 0.2513 | 0.2513 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0149 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | fmrfamide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0029 | 0.086 | 0.086 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus multilocularis | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0021 | 0.0274 | 0.3182 |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptide s receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | opsin-like receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0274 | 0.0127 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0053 | 0.2688 | 0.2688 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | hypothetical protein | 0.0138 | 0.8886 | 0.8886 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0051 | 0.2513 | 0.2513 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Entamoeba histolytica | cysteine protease, putative | 0.0029 | 0.086 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0149 | 0.0149 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0149 | 0.0554 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | follicle stimulating hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0149 | 0.5 |
Echinococcus granulosus | cathepsin l1 | 0.0021 | 0.0274 | 0.0274 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | cathepsin L-like precursor | 0.0021 | 0.0274 | 0.0274 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Plasmodium vivax | vivapain-2 | 0.0029 | 0.086 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | cysteine protease | 0.0029 | 0.086 | 0.0722 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Schistosoma mansoni | biogenic amine receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Giardia lamblia | Cathepsin B precursor | 0.0053 | 0.2688 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | AKH receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin b | 0.0153 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0153 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | sex peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Toxoplasma gondii | cathepsin B | 0.0053 | 0.2688 | 1 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0149 | 0.0149 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | fmrfamide receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0051 | 0.2513 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Leishmania major | cysteine peptidase A (CPA) | 0.0029 | 0.086 | 0.2802 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | Cathepsin L homolog | 0.0029 | 0.086 | 0.2619 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cysteine protease | 0.0029 | 0.086 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.086 | 0.0722 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0149 | 0.5 |
Brugia malayi | Melatonin receptor type 1A | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Brugia malayi | putative neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0149 | 0.1732 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus multilocularis | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0149 | 0.0149 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0029 | 0.086 | 0.086 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Brugia malayi | Dopamine receptor protein 2 | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | cathepsin B | 0.0053 | 0.2688 | 0.2577 |
Schistosoma mansoni | biogenic amine receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0021 | 0.0274 | 0.0274 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0029 | 0.086 | 1 |
Schistosoma mansoni | histamine h1 receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0029 | 0.086 | 0.0722 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | myosin xvIII | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | allatostatin A receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 12 % | The concentration to inhibit cell proliferation of PC3 human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 14 % | The concentration to inhibit cell proliferation of PC3 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 18 % | The concentration to inhibit colony formation of Ishikawa human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 18 % | The concentration to inhibit colony formation of MCF-7 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 18 % | The concentration to inhibit cell proliferation of MCF-7 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 18 % | The concentration to inhibit cell proliferation of MDA-MB-231 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 19 % | The concentration to inhibit cell proliferation of MDA-MB-231 human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 20 % | The concentration to inhibit cell proliferation of MCF-7 human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 21 % | The concentration to inhibit colony formation of PC3 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 32 % | The concentration to inhibit cell proliferation of LNCaP human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 40 % | The concentration to inhibit cell proliferation of LNCaP human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 44 % | The concentration to inhibit colony formation of MDA-MB-231 humantumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 45 % | The concentration to inhibit colony formation of MCF-7 human tumour cell lines | ChEMBL. | 9341910 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.