Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Rattus norvegicus | Anandamide amidohydrolase | Starlite/ChEMBL | References |
Species | Potential target | Known druggable target | Length | Alignment span | Identity |
---|---|---|---|---|---|
Onchocerca volvulus | Anandamide amidohydrolase | 579 aa | 539 aa | 34.7 % | |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | Anandamide amidohydrolase | 579 aa | 470 aa | 28.3 % |
Echinococcus granulosus | fatty acid amide hydrolase 1 | Anandamide amidohydrolase | 579 aa | 470 aa | 28.7 % |
Schistosoma japonicum | Fatty-acid amide hydrolase 1, putative | Anandamide amidohydrolase | 579 aa | 499 aa | 24.6 % |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.0144 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0144 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0144 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0144 | 0 | 0.5 |
Brugia malayi | Deoxynucleoside kinase family protein | 0.0144 | 0 | 0.5 |
Schistosoma mansoni | thymidine kinase | 0.0641 | 0.6471 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0144 | 0 | 0.5 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0144 | 0 | 0.5 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0144 | 0 | 0.5 |
Echinococcus granulosus | thymidine kinase | 0.0641 | 0.6471 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0144 | 0 | 0.5 |
Echinococcus multilocularis | thymidine kinase | 0.0641 | 0.6471 | 1 |
Echinococcus granulosus | thymidine kinase | 0.0641 | 0.6471 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0144 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0144 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0144 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0144 | 0 | 0.5 |
Echinococcus multilocularis | transfer RNA-Ile | 0.0641 | 0.6471 | 1 |
Echinococcus multilocularis | thymidine kinase | 0.0641 | 0.6471 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0144 | 0 | 0.5 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0144 | 0 | 0.5 |
Echinococcus granulosus | Thymidine kinase 2 mitochondrial | 0.0641 | 0.6471 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0144 | 0 | 0.5 |
Loa Loa (eye worm) | deoxynucleoside kinase | 0.0144 | 0 | 0.5 |
Entamoeba histolytica | deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein | 0.0144 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0144 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0144 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.