Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Sodium/hydrogen exchanger 3 | 0.0066 | 0.1044 | 0.5 |
Schistosoma mansoni | sodium/hydrogen exchanger 2 (nhe2) | 0.0066 | 0.1044 | 1 |
Loa Loa (eye worm) | sodium/hydrogen exchanger | 0.0066 | 0.1044 | 0.1071 |
Echinococcus granulosus | sodium:hydrogen exchanger 2 nhe2 | 0.0066 | 0.1044 | 1 |
Echinococcus granulosus | sodium:hydrogen exchanger | 0.0066 | 0.1044 | 1 |
Echinococcus multilocularis | sodium:hydrogen exchanger 2 (nhe2) | 0.0054 | 0.0754 | 0.7224 |
Echinococcus multilocularis | sodium:hydrogen exchanger 2 (nhe2) | 0.0066 | 0.1044 | 1 |
Echinococcus multilocularis | sodium:hydrogen exchanger | 0.0066 | 0.1044 | 1 |
Onchocerca volvulus | Sodium\/hydrogen exchanger homolog | 0.0066 | 0.1044 | 0.1044 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1044 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1044 | 0.1071 |
Loa Loa (eye worm) | hypothetical protein | 0.0437 | 0.9524 | 0.977 |
Echinococcus granulosus | sodium:hydrogen exchanger 2 nhe2 | 0.0066 | 0.1044 | 1 |
Echinococcus granulosus | sodium:hydrogen exchanger 2 (nhe2) | 0.0054 | 0.0754 | 0.7224 |
Brugia malayi | nuclear hormone receptor | 0.0447 | 0.9749 | 1 |
Loa Loa (eye worm) | NHE-3 | 0.0066 | 0.1044 | 0.1071 |
Onchocerca volvulus | Sodium\/hydrogen exchanger homolog | 0.0066 | 0.1044 | 0.1044 |
Echinococcus granulosus | sodium:hydrogen exchanger 2 nhe2 | 0.0066 | 0.1044 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0447 | 0.9749 | 1 |
Onchocerca volvulus | Sodium\/hydrogen exchanger homolog | 0.0066 | 0.1044 | 0.1044 |
Echinococcus multilocularis | sodium:hydrogen exchanger | 0.0066 | 0.1044 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1044 | 0.1071 |
Echinococcus granulosus | sodium:hydrogen exchanger | 0.0066 | 0.1044 | 1 |
Brugia malayi | sodium/hydrogen exchanger 3 family protein | 0.0066 | 0.1044 | 0.1071 |
Loa Loa (eye worm) | sodium/hydrogen exchanger 3 family protein | 0.0066 | 0.1044 | 0.1071 |
Schistosoma mansoni | sodium/hydrogen exchanger | 0.0066 | 0.1044 | 1 |
Echinococcus multilocularis | sodium:hydrogen exchanger 2 (nhe2) | 0.0066 | 0.1044 | 1 |
Echinococcus multilocularis | sodium:hydrogen exchanger 2 (nhe2) | 0.0066 | 0.1044 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.