Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | histone deacetylase 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | protein MICAL 3 | 0.0146 | 0.6701 | 0.5891 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0113 | 0.4412 | 0.304 |
Trypanosoma brucei | kynurenine 3-monooxygenase, putative | 0.0146 | 0.6701 | 0.6701 |
Trypanosoma brucei | Monooxygenase, putative | 0.0146 | 0.6701 | 0.6701 |
Echinococcus granulosus | ubiquinone biosynthesis monooxygenase COQ6 | 0.0146 | 0.6701 | 0.5891 |
Trypanosoma cruzi | Monooxygenase, putative | 0.0146 | 0.6701 | 0.5891 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1971 | 0.5 |
Mycobacterium ulcerans | FAD-linked oxidoreductase | 0.0146 | 0.6701 | 0.5 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0195 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0103 | 0.3742 | 0.3742 |
Mycobacterium ulcerans | FAD-dependent oxidoreductase | 0.0146 | 0.6701 | 0.5 |
Mycobacterium ulcerans | oxidoreductase | 0.0146 | 0.6701 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.6701 | 0.6701 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1971 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1971 | 0.5 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0146 | 0.6701 | 0.5 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0146 | 0.6701 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0146 | 0.6701 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0146 | 0.6701 | 0.5891 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0077 | 0.1971 | 0.5 |
Mycobacterium ulcerans | oxidoreductase | 0.0146 | 0.6701 | 0.5 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0099 | 0.3477 | 0.1876 |
Plasmodium vivax | hypothetical protein, conserved | 0.0146 | 0.6701 | 1 |
Toxoplasma gondii | FAD binding domain-containing protein | 0.0146 | 0.6701 | 1 |
Mycobacterium ulcerans | membrane-associated oxidoreductase | 0.0146 | 0.6701 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | 2-polyprenyl-6-methoxyphenol 4-hydroxylase | 0.0146 | 0.6701 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0146 | 0.6701 | 0.5 |
Echinococcus granulosus | protein MICAL 3 | 0.0146 | 0.6701 | 0.5891 |
Schistosoma mansoni | histone deacetylase | 0.0077 | 0.1971 | 0.1971 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0195 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0077 | 0.1971 | 0.5 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0113 | 0.4412 | 0.304 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1971 | 0.5 |
Giardia lamblia | Histone deacetylase | 0.0077 | 0.1971 | 0.5 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0195 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0146 | 0.6701 | 0.5891 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0195 | 1 | 1 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0195 | 1 | 1 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0195 | 1 | 1 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0195 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0077 | 0.1971 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0146 | 0.6701 | 0.5891 |
Trypanosoma brucei | histone deacetylase 1 | 0.0077 | 0.1971 | 0.1971 |
Echinococcus multilocularis | ubiquinone biosynthesis monooxygenase COQ6 | 0.0146 | 0.6701 | 0.5891 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0146 | 0.6701 | 0.5 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0195 | 1 | 1 |
Plasmodium falciparum | FAD-dependent monooxygenase, putative | 0.0146 | 0.6701 | 1 |
Chlamydia trachomatis | monooxygenase | 0.0146 | 0.6701 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0103 | 0.3742 | 0.2205 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1971 | 0.5 |
Mycobacterium leprae | possibleputative FAD-linked oxidoreductase | 0.0146 | 0.6701 | 0.5 |
Schistosoma mansoni | histone deacetylase | 0.0077 | 0.1971 | 0.1971 |
Schistosoma mansoni | monoxygenase | 0.0146 | 0.6701 | 0.6701 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0077 | 0.1971 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.6701 | 0.5891 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0195 | 1 | 1 |
Plasmodium vivax | FAD-dependent monooxygenase, putative | 0.0146 | 0.6701 | 1 |
Mycobacterium ulcerans | oxidoreductase GMC-type | 0.0146 | 0.6701 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0146 | 0.6701 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0146 | 0.6701 | 0.5 |
Toxoplasma gondii | FAD binding domain-containing protein | 0.0146 | 0.6701 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0146 | 0.6701 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.