Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0216 | 0.0216 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0038 | 0.0561 | 0.0538 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0023 | 0.0023 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0363 | 0.0409 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0216 | 0.0243 |
Onchocerca volvulus | 0.002 | 0.0216 | 0.1218 | |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0467 | 0.0525 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0216 | 0.0216 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.0453 | 0.889 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.002 | 0.0216 | 0.1218 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.017 | 0.3205 | 0.3605 |
Schistosoma mansoni | alpha-glucosidase | 0.0146 | 0.2732 | 0.3073 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.0148 | 0.0167 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0.0171 | 0.5 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0017 | 0.0148 | 0.0167 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0216 | 0.0243 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0018 | 0.0171 | 0.5 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0561 | 0.0538 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0065 | 0.1118 | 0.1118 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.0453 | 0.889 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0216 | 0.0243 |
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.0453 | 0.889 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0113 | 0.0127 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0038 | 0.0561 | 0.0631 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.0395 | 0.0444 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.0761 | 0.0856 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0216 | 0.0243 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0113 | 0.0113 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0038 | 0.0561 | 0.0631 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0216 | 0.0216 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0113 | 0.0127 |
Onchocerca volvulus | Uncharacterized family 31 glucosidase KIAA1161 homolog | 0.0014 | 0.0088 | 0.0497 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0148 | 0.0148 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0019 | 0.018 | 0.0203 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0216 | 0.0243 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0216 | 0.0243 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0761 | 0.0856 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0017 | 0.0148 | 0.0069 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0395 | 0.0444 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0216 | 0.0243 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0216 | 0.0243 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0216 | 0.0243 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0216 | 0.0243 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0065 | 0.1118 | 0.1258 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0171 | 0.0095 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0023 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0148 | 0.0148 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0216 | 0.0243 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0216 | 0.0243 |
Schistosoma mansoni | alpha-glucosidase | 0.0146 | 0.2732 | 0.3073 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0216 | 0.0243 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0038 | 0.0561 | 0.0538 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.0148 | 0.0167 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0216 | 0.0243 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0038 | 0.0561 | 0.0561 |
Echinococcus granulosus | geminin | 0.0176 | 0.3341 | 0.3758 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.0861 | 0.0815 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0014 | 0.0088 | 0.0099 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0216 | 0.0243 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0023 | 0.0023 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0216 | 0.0243 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0216 | 0.0243 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0761 | 0.0856 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0216 | 0.0243 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0216 | 0.0243 |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.0395 | 0.0444 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0038 | 0.0561 | 0.0472 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0467 | 0.0525 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0171 | 0.0193 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0216 | 0.0243 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0216 | 0.0216 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0064 | 0.1086 | 0.1222 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0038 | 0.0561 | 0.0631 |
Schistosoma mansoni | phd/f-box containing protein | 0.0017 | 0.0148 | 0.0167 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.0772 | 0.0772 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0216 | 0.0216 |
Brugia malayi | jmjC domain containing protein | 0.0065 | 0.1118 | 0.1258 |
Schistosoma mansoni | jumonji domain containing protein | 0.0017 | 0.0148 | 0.0167 |
Echinococcus multilocularis | geminin | 0.0176 | 0.3341 | 0.3758 |
Echinococcus granulosus | dnaJ subfamily B | 0.0395 | 0.7726 | 0.8691 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.017 | 0.3205 | 0.3605 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0216 | 0.0243 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0171 | 0.0193 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0216 | 0.0243 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0148 | 0.0148 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0561 | 0.0538 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0561 | 0.0538 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0561 | 0.0538 |
Plasmodium falciparum | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.0453 | 0.889 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0216 | 0.0243 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0216 | 0.0243 |
Leishmania major | hypothetical protein, conserved | 0.0017 | 0.0148 | 0.0069 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0216 | 0.0216 |
Mycobacterium ulcerans | hypothetical protein | 0.0198 | 0.3773 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0113 | 0.0127 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0561 | 0.0538 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.017 | 0.3205 | 0.3605 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0011 | 0.0023 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.017 | 0.3205 | 0.3205 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0113 | 0.0113 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.3341 | 0.3758 |
Loa Loa (eye worm) | hypothetical protein | 0.0509 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0216 | 0.0243 |
Schistosoma mansoni | protein phosphatase 2C | 0.0017 | 0.0148 | 0.0167 |
Toxoplasma gondii | isoprenylcysteine carboxyl methyltransferase (icmt) family protein | 0.0453 | 0.889 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0216 | 0.0243 |
Echinococcus granulosus | phd:f box containing protein | 0.0017 | 0.0148 | 0.0167 |
Echinococcus granulosus | protein S isoprenylcysteine O methyltransferase | 0.0453 | 0.889 | 1 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0171 | 0.0026 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.0148 | 0.0167 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0113 | 0.0127 |
Trypanosoma brucei | prenyl protein specific carboxyl methyltransferase | 0.0453 | 0.889 | 1 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0216 | 0.0243 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0216 | 0.0243 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0761 | 0.0856 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0017 | 0.0148 | 0.0167 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0561 | 0.0538 |
Schistosoma mansoni | jumonji domain containing protein | 0.0064 | 0.1086 | 0.1222 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0113 | 0.0127 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0216 | 0.0243 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0038 | 0.0561 | 0.0538 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.0761 | 0.0761 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0761 | 0.0856 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0171 | 0.0193 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0171 | 0.0026 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0113 | 0.0127 |
Onchocerca volvulus | 0.0028 | 0.0363 | 0.205 | |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0017 | 0.0148 | 0.0069 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0216 | 0.0243 |
Onchocerca volvulus | 0.0098 | 0.1772 | 1 | |
Giardia lamblia | Isoprenylcysteine carboxyl methyltransferase | 0.0453 | 0.889 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0216 | 0.0243 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0171 | 0.0095 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0363 | 0.0409 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0017 | 0.0148 | 0.0167 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.0148 | 0.0148 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0064 | 0.1086 | 0.1222 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0017 | 0.0148 | 0.0167 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0017 | 0.0148 | 0.0167 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0019 | 0.018 | 0.0203 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.0148 | 0.0148 |
Echinococcus multilocularis | phd:f box containing protein | 0.0017 | 0.0148 | 0.0167 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0023 | 0.0023 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0065 | 0.1118 | 0.1258 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0038 | 0.0561 | 0.0538 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0113 | 0.0127 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0017 | 0.0148 | 0.0069 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0038 | 0.0561 | 0.0538 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0216 | 0.0243 |
Mycobacterium tuberculosis | Conserved hypothetical membrane protein | 0.0198 | 0.3773 | 1 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0018 | 0.0171 | 0.0095 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0171 | 0.0193 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0216 | 0.0243 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.0148 | 0.0148 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0011 | 0.0023 | 0.0026 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.3341 | 0.3758 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0363 | 0.0363 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0011 | 0.0023 | 0.0023 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0216 | 0.0243 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0395 | 0.7726 | 0.8691 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0467 | 0.0467 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0171 | 0.0095 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0023 | 0.0023 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0216 | 0.0243 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0216 | 0.0216 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0761 | 0.0856 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0216 | 0.0216 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0023 | 0.0026 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0216 | 0.0243 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.0453 | 0.889 | 1 |
Plasmodium vivax | protein-S-isoprenylcysteine O-methyltransferase, putative | 0.0453 | 0.889 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0113 | 0.0127 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0113 | 0.0127 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0171 | 0.0026 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0065 | 0.1118 | 0.1258 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0059 | 0.0987 | 0.111 |
Brugia malayi | protein-S isoprenylcysteine O-methyltransferase, putative | 0.0453 | 0.889 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0011 | 0.0023 | 0.0026 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.002 | 0.0216 | 0.1218 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0216 | 0.0243 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0113 | 0.0127 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0216 | 0.0243 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0216 | 0.0243 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0216 | 0.0243 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.0772 | 0.0869 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0113 | 0.0127 |
Loa Loa (eye worm) | protein-S isoprenylcysteine O-methyltransferase | 0.0453 | 0.889 | 0.889 |
Schistosoma mansoni | hypothetical protein | 0.0395 | 0.7726 | 0.8691 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0113 | 0.0127 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0216 | 0.0243 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0216 | 0.0243 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0761 | 0.0856 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0017 | 0.0148 | 0.0167 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0023 | 0.0023 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.017 | 0.3205 | 0.3605 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0216 | 0.0243 |
Trypanosoma cruzi | prenyl protein specific carboxyl methyltransferase, putative | 0.0453 | 0.889 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0171 | 0.0193 |
Schistosoma mansoni | protein-s-isoprenylcysteine o-methyltransferase | 0.0453 | 0.889 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.0171 | 0.0095 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0216 | 0.0243 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0.0171 | 0.0095 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0216 | 0.0243 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0216 | 0.0216 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0064 | 0.1086 | 0.1222 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0038 | 0.0561 | 0.0538 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0216 | 0.0216 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.0023 | 0.0026 |
Entamoeba histolytica | prenyl cysteine carboxyl methyltransferase, putative | 0.0453 | 0.889 | 1 |
Leishmania major | prenyl protein specific carboxyl methyltransferase, putative | 0.0453 | 0.889 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0038 | 0.0561 | 0.0538 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0216 | 0.0216 |
Brugia malayi | jmjC domain containing protein | 0.0064 | 0.1086 | 0.1222 |
Trypanosoma brucei | glucosidase, putative | 0.0038 | 0.0561 | 0.0538 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0017 | 0.0148 | 0.0167 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.0023 | 0.0026 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0216 | 0.0243 |
Trichomonas vaginalis | protein-S isoprenylcysteine O-methyltransferase, putative | 0.0453 | 0.889 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.0148 | 0.0167 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0761 | 0.0856 |
Schistosoma mansoni | alpha glucosidase | 0.0038 | 0.0561 | 0.0631 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0216 | 0.0243 |
Onchocerca volvulus | Bile acid receptor homolog | 0.002 | 0.0216 | 0.1218 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0395 | 0.0444 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0216 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0772 | 0.0772 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0216 | 0.0243 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.0772 | 0.0869 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0216 | 0.0216 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0011 | 0.0023 | 0.0026 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0171 | 0.0095 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0216 | 0.0243 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0023 | 0.0026 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0171 | 0.0171 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0017 | 0.0148 | 0.0167 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0561 | 0.0538 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0216 | 0.0243 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0216 | 0.0216 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0216 | 0.0243 |
Echinococcus multilocularis | 0.0453 | 0.889 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 15.8 nM | Antagonist activity at cloned muscarinic M1 receptor expressed in CHO cells by measuring calcium mobilization | ChEMBL. | 17911022 |
IC50 (functional) | = 21.2 nM | Antagonist activity at cloned muscarinic M3 receptor expressed in CHO cells by measuring calcium mobilization | ChEMBL. | 17911022 |
IC50 (functional) | = 60.8 nM | Antagonist activity at cloned muscarinic M2 receptor expressed in CHO cells by measuring calcium mobilization | ChEMBL. | 17911022 |
Ratio IC50 (binding) | = 0.8 | Selectivity for cloned muscarinic M3 receptor over cloned muscarinic M1 receptor | ChEMBL. | 17911022 |
Ratio IC50 (binding) | = 2.9 | Selectivity for cloned muscarinic M3 receptor over cloned muscarinic M2 receptor | ChEMBL. | 17911022 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.