Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | somatostatin receptor 5 | Starlite/ChEMBL | References |
Species | Potential target | Known druggable target | Length | Alignment span | Identity |
---|---|---|---|---|---|
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | somatostatin receptor 5 | 364 aa | 392 aa | 19.4 % |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.1684 | 0.3792 | 1 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.1676 | 0.3768 | 0.3768 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0725 | 0.0991 | 0.0991 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.381 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.1684 | 0.3792 | 0.5 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.1676 | 0.3768 | 1 |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.1684 | 0.3792 | 1 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.381 | 1 | 1 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.1459 | 0.3134 | 1 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.381 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0725 | 0.0991 | 0.0413 |
Loa Loa (eye worm) | hypothetical protein | 0.1084 | 0.2037 | 0.1527 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.1676 | 0.3768 | 0.3768 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.381 | 1 | 1 |
Chlamydia trachomatis | oxoacyl-ACP synthase III | 0.1684 | 0.3792 | 0.5 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0725 | 0.0991 | 0.0991 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.0725 | 0.0991 | 0.1986 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.1676 | 0.3768 | 0.3768 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.1676 | 0.3768 | 1 |
Brugia malayi | hypothetical protein | 0.1084 | 0.2037 | 0.1162 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.1676 | 0.3768 | 1 |
Mycobacterium ulcerans | beta-ketoacyl synthase-like protein | 0.1684 | 0.3792 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0725 | 0.0991 | 0.0991 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.1676 | 0.3768 | 1 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.1676 | 0.3768 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.1676 | 0.3768 | 0.3083 |
Trypanosoma brucei | prolyl endopeptidase | 0.0725 | 0.0991 | 0.1986 |
Plasmodium falciparum | beta-ketoacyl-ACP synthase III | 0.1684 | 0.3792 | 0.5 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.381 | 1 | 1 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.049 | 0.0303 | 0.5 |
Trypanosoma cruzi | prolyl endopeptidase | 0.0725 | 0.0991 | 0.1986 |
Plasmodium vivax | beta-ketoacyl-acyl carrier protein synthase III precursor, putative | 0.1684 | 0.3792 | 0.5 |
Echinococcus granulosus | prolyl endopeptidase | 0.0725 | 0.0991 | 0.0991 |
Mycobacterium tuberculosis | 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) | 0.1684 | 0.3792 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.