Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | phospholipase D2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0061 | 0.8617 | 0.5 |
Trichomonas vaginalis | glucose-6-phosphate translocase, putative | 0.0061 | 0.8617 | 0.5 |
Trichomonas vaginalis | transport proetin, putative | 0.0061 | 0.8617 | 0.5 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0056 | 0.7678 | 0.7678 |
Trypanosoma cruzi | cardiolipin synthetase, putative | 0.0024 | 0.1973 | 0.5 |
Trichomonas vaginalis | glucarate, hexuronate transporter, putative | 0.0061 | 0.8617 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0061 | 0.8617 | 0.5 |
Entamoeba histolytica | phospholipase D, putative | 0.0069 | 1 | 1 |
Trichomonas vaginalis | Regulatory protein uhpC, putative | 0.0061 | 0.8617 | 0.5 |
Echinococcus granulosus | phospholipase D1 | 0.0069 | 1 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.7678 | 0.5 |
Trypanosoma brucei | cardiolipin synthetase | 0.0024 | 0.1973 | 0.5 |
Schistosoma mansoni | phospholipase D | 0.0069 | 1 | 1 |
Brugia malayi | Phospholipase D. Active site motif family protein | 0.0024 | 0.1973 | 0.1973 |
Giardia lamblia | Sugar transport family protein | 0.0061 | 0.8617 | 0.5 |
Onchocerca volvulus | Putative phospholipase D | 0.0013 | 0 | 0.5 |
Trichomonas vaginalis | Regulatory protein uhpC, putative | 0.0061 | 0.8617 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.8027 | 1 |
Trypanosoma cruzi | cardiolipin synthetase, putative | 0.0024 | 0.1973 | 0.5 |
Entamoeba histolytica | phospholipase D, putative | 0.0069 | 1 | 1 |
Mycobacterium tuberculosis | Probable conserved integral membrane protein | 0.0061 | 0.8617 | 1 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0052 | 0.7005 | 0.8727 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.5702 | 0.7103 |
Echinococcus multilocularis | phospholipase D1 | 0.0069 | 1 | 1 |
Trichomonas vaginalis | Hexuronate transporter, putative | 0.0061 | 0.8617 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.5702 | 0.7103 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0061 | 0.8617 | 0.5 |
Echinococcus granulosus | phospholipase D | 0.0061 | 0.8562 | 0.8562 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.8027 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0061 | 0.8617 | 0.5 |
Toxoplasma gondii | phospholipase D active site domain-containing protein | 0.0024 | 0.1973 | 0.5 |
Echinococcus multilocularis | phospholipase D | 0.0061 | 0.8562 | 0.8562 |
Trypanosoma brucei | cardiolipin synthetase, putative | 0.0024 | 0.1973 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0061 | 0.8617 | 0.5 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.7678 | 0.7678 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0061 | 0.8617 | 0.5 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0056 | 0.7678 | 1 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.7678 | 0.7678 |
Wolbachia endosymbiont of Brugia malayi | major facilitator superfamily permease | 0.0061 | 0.8617 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0061 | 0.8617 | 0.5 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.7678 | 0.5 |
Chlamydia trachomatis | hexose phosphate transporter | 0.0061 | 0.8617 | 0.5 |
Trichomonas vaginalis | glucarate, hexuronate transporter, putative | 0.0061 | 0.8617 | 0.5 |
Brugia malayi | hypothetical protein | 0.0061 | 0.8617 | 0.8617 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.