Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0068 | 0.1263 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0068 | 0.1263 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0068 | 0.1263 | 0.1263 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0068 | 0.1263 | 0.1263 |
Echinococcus granulosus | acetylcholinesterase | 0.0405 | 1 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.0068 | 0.1263 | 0.1263 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0068 | 0.1263 | 0.5 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0068 | 0.1263 | 0.1263 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0068 | 0.1263 | 0.1263 |
Loa Loa (eye worm) | hypothetical protein | 0.0405 | 1 | 1 |
Echinococcus granulosus | neuroligin | 0.0068 | 0.1263 | 0.1263 |
Brugia malayi | Carboxylesterase family protein | 0.0068 | 0.1263 | 0.1263 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.1263 | 0.1263 |
Echinococcus multilocularis | acetylcholinesterase | 0.0405 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0405 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0405 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.1263 | 0.1263 |
Echinococcus multilocularis | acetylcholinesterase | 0.0405 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0068 | 0.1263 | 0.5 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0068 | 0.1263 | 0.1263 |
Loa Loa (eye worm) | hypothetical protein | 0.0405 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0068 | 0.1263 | 0.1263 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.1263 | 0.1263 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0405 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0068 | 0.1263 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0068 | 0.1263 | 0.1263 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0068 | 0.1263 | 0.1263 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0068 | 0.1263 | 0.1263 |
Onchocerca volvulus | 0.0068 | 0.1263 | 1 | |
Onchocerca volvulus | 0.0068 | 0.1263 | 1 | |
Loa Loa (eye worm) | carboxylesterase | 0.0068 | 0.1263 | 0.1263 |
Onchocerca volvulus | 0.0068 | 0.1263 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.1263 | 0.1263 |
Loa Loa (eye worm) | carboxylesterase | 0.0405 | 1 | 1 |
Schistosoma mansoni | gliotactin | 0.0068 | 0.1263 | 0.1263 |
Onchocerca volvulus | 0.0068 | 0.1263 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.1263 | 0.1263 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0068 | 0.1263 | 0.1263 |
Onchocerca volvulus | 0.0068 | 0.1263 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.1263 | 0.1263 |
Brugia malayi | Carboxylesterase family protein | 0.0068 | 0.1263 | 0.1263 |
Echinococcus granulosus | acetylcholinesterase | 0.0405 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0405 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0068 | 0.1263 | 0.1263 |
Brugia malayi | Carboxylesterase family protein | 0.0068 | 0.1263 | 0.1263 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0068 | 0.1263 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0405 | 1 | 1 |
Echinococcus multilocularis | neuroligin | 0.0068 | 0.1263 | 0.1263 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0068 | 0.1263 | 0.1263 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.1263 | 0.1263 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0068 | 0.1263 | 0.1263 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0068 | 0.1263 | 0.1263 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 22 % | Inhibition of carbohydrate-dependent galectin1 binding to human Capan1 cell surface at 2mM | ChEMBL. | 17095217 |
Activity (functional) | = 22 % | Inhibition of carbohydrate-dependent galectin1 binding to human Capan1 cell surface at 2mM | ChEMBL. | 17095217 |
Inhibition (binding) | = 38 % | Inhibition of carbohydrate-dependent human galectin1 binding at 10mM by solid phase assay | ChEMBL. | 17095217 |
Inhibition (binding) | = 38 % | Inhibition of carbohydrate-dependent human galectin1 binding at 10mM by solid phase assay | ChEMBL. | 17095217 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.