Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0026 | 0.0335 | 0.0498 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0387 | 0.0577 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.0387 | 0.0054 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0387 | 0.0577 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0335 | 0.0498 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0335 | 0.0498 |
Onchocerca volvulus | 0.0028 | 0.0387 | 0.0703 | |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0129 | 0.3446 | 0.3219 |
Brugia malayi | nuclear receptor NHR-88 | 0.0026 | 0.0335 | 0.0498 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0026 | 0.0335 | 0.0498 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0026 | 0.0335 | 0.0498 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.0387 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1082 | 0.1612 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.0387 | 0.0054 |
Brugia malayi | follicle stimulating hormone receptor | 0.0237 | 0.6714 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0387 | 0.0577 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0026 | 0.0335 | 0.0498 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0026 | 0.0335 | 0.0498 |
Brugia malayi | nuclear hormone receptor | 0.0026 | 0.0335 | 0.0498 |
Schistosoma mansoni | hypothetical protein | 0.0129 | 0.3446 | 0.7993 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0026 | 0.0335 | 0.0498 |
Onchocerca volvulus | 0.0028 | 0.0387 | 0.0703 | |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0026 | 0.0335 | 0.0498 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0372 | 0.0554 |
Schistosoma mansoni | lamin | 0.0028 | 0.0387 | 0.0135 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0335 | 0.0498 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0335 | 0.0498 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0026 | 0.0335 | 0.0498 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0026 | 0.0335 | 0.0498 |
Echinococcus multilocularis | lamin | 0.0028 | 0.0387 | 0.0054 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0026 | 0.0335 | 0.0498 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0335 | 0.0498 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0026 | 0.0335 | 0.0498 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0026 | 0.0335 | 0.0498 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0154 | 0.4227 | 0.4027 |
Echinococcus multilocularis | tumor protein p63 | 0.0345 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0335 | 0.0498 |
Schistosoma mansoni | lamin | 0.0028 | 0.0387 | 0.0135 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0026 | 0.0335 | 0.0498 |
Brugia malayi | steroid hormone receptor | 0.0026 | 0.0335 | 0.0498 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0026 | 0.0335 | 0.0498 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0026 | 0.0335 | 0.0498 |
Echinococcus granulosus | lamin | 0.0028 | 0.0387 | 0.0054 |
Schistosoma mansoni | thyroid hormone receptor | 0.0154 | 0.4227 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0026 | 0.0335 | 0.0498 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.0387 | 0.0135 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0026 | 0.0335 | 0.0498 |
Schistosoma mansoni | thyroid hormone receptor | 0.0154 | 0.4227 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0335 | 0.0498 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0026 | 0.0335 | 0.0498 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0237 | 0.6714 | 1 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0051 | 0.1082 | 0.1922 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.0387 | 0.0577 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0026 | 0.0335 | 0.0498 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0026 | 0.0335 | 0.0498 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.0387 | 0.0577 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0129 | 0.3446 | 0.3219 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0026 | 0.0335 | 0.0498 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0026 | 0.0335 | 0.0498 |
Brugia malayi | ecdysteroid receptor | 0.0026 | 0.0335 | 0.0498 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0026 | 0.0335 | 0.0498 |
Onchocerca volvulus | 0.0051 | 0.1082 | 1 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0026 | 0.0335 | 0.0498 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0335 | 0.0498 |
Echinococcus multilocularis | musashi | 0.0028 | 0.0387 | 0.0054 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.