Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tyrosine kinase | 0.0651 | 0.5113 | 0.5113 |
Schistosoma mansoni | fatty acid binding protein | 0.0132 | 0.0564 | 0.0564 |
Loa Loa (eye worm) | lipocalin/cytosolic fatty-acid binding protein family protein | 0.054 | 0.4139 | 0.4139 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0141 | 0.0638 | 0.0638 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0141 | 0.0638 | 0.0638 |
Echinococcus granulosus | tyrosine kinase | 0.0141 | 0.0638 | 0.0638 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0155 | 0.0765 | 0.0765 |
Echinococcus multilocularis | fatty acid binding protein FABP2 | 0.0132 | 0.0564 | 0.0564 |
Echinococcus granulosus | fatty acid binding protein FABP2 | 0.0132 | 0.0564 | 0.0564 |
Echinococcus multilocularis | 0.0373 | 0.2671 | 0.2671 | |
Schistosoma mansoni | tyrosine kinase | 0.064 | 0.5016 | 0.5016 |
Schistosoma mansoni | tyrosine kinase | 0.0155 | 0.0765 | 0.0765 |
Schistosoma mansoni | tyrosine kinase | 0.0155 | 0.0765 | 0.0765 |
Brugia malayi | Protein kinase domain containing protein | 0.0389 | 0.2813 | 0.2813 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0141 | 0.0638 | 0.0638 |
Schistosoma mansoni | tyrosine kinase | 0.1208 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0155 | 0.0765 | 0.0765 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0155 | 0.0765 | 0.0765 |
Schistosoma mansoni | fatty acid binding protein | 0.0132 | 0.0564 | 0.0564 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0155 | 0.0765 | 0.0765 |
Echinococcus multilocularis | insulin receptor | 0.0389 | 0.2813 | 0.2813 |
Schistosoma mansoni | tyrosine kinase | 0.0389 | 0.2813 | 0.2813 |
Loa Loa (eye worm) | SRC-1 | 0.0155 | 0.0765 | 0.0765 |
Leishmania major | 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein | 0.0164 | 0.0839 | 0.5 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0164 | 0.0839 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase HCK | 0.0126 | 0.0508 | 0.0508 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0155 | 0.0765 | 0.0765 |
Loa Loa (eye worm) | TK protein kinase | 0.0126 | 0.0508 | 0.0508 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0155 | 0.0765 | 0.0765 |
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative | 0.0164 | 0.0839 | 0.5 |
Echinococcus multilocularis | fatty acid binding protein FABP2 | 0.0132 | 0.0564 | 0.0564 |
Brugia malayi | Lipocalin / cytosolic fatty-acid binding protein family protein | 0.054 | 0.4139 | 0.4139 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0164 | 0.0839 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.064 | 0.5016 | 0.5016 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0141 | 0.0638 | 0.0638 |
Brugia malayi | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | 0.0164 | 0.0839 | 0.0839 |
Schistosoma mansoni | tyrosine kinase | 0.0651 | 0.5113 | 0.5113 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0155 | 0.0765 | 0.0765 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.1208 | 1 | 1 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.1208 | 1 | 1 |
Loa Loa (eye worm) | TK protein kinase | 0.0141 | 0.0638 | 0.0638 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.013 | 0.0541 | 0.0541 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0155 | 0.0765 | 0.0765 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0651 | 0.5113 | 0.5113 |
Echinococcus granulosus | insulin receptor | 0.0389 | 0.2813 | 0.2813 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0389 | 0.2813 | 0.2813 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.0839 | 0.0839 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0651 | 0.5113 | 0.5113 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0155 | 0.0765 | 0.0765 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0155 | 0.0765 | 0.0765 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0155 | 0.0765 | 0.0765 |
Brugia malayi | protein-tyrosine kinase | 0.0141 | 0.0638 | 0.0638 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0141 | 0.0638 | 0.0638 |
Echinococcus granulosus | fatty acid binding protein FABP2 | 0.0132 | 0.0564 | 0.0564 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0164 | 0.0839 | 0.5 |
Echinococcus granulosus | epidermal growth factor receptor | 0.1208 | 1 | 1 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0164 | 0.0839 | 0.5 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.0164 | 0.0839 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0155 | 0.0765 | 0.0765 |
Echinococcus granulosus | tyrosine protein kinase HCK | 0.0126 | 0.0508 | 0.0508 |
Schistosoma mansoni | tyrosine kinase | 0.0389 | 0.2813 | 0.2813 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0155 | 0.0765 | 0.0765 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0155 | 0.0765 | 0.0765 |
Schistosoma mansoni | tyrosine kinase | 0.064 | 0.5016 | 0.5016 |
Mycobacterium ulcerans | hypothetical protein | 0.0164 | 0.0839 | 0.5 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0389 | 0.2813 | 0.2813 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0389 | 0.2813 | 0.2813 |
Brugia malayi | SRC-1 | 0.0155 | 0.0765 | 0.0765 |
Entamoeba histolytica | steroid 5-alpha reductase, putative | 0.0164 | 0.0839 | 1 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0651 | 0.5113 | 0.5113 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0155 | 0.0765 | 0.0765 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0164 | 0.0839 | 0.5 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0155 | 0.0765 | 0.0765 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.013 | 0.0541 | 0.0541 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0155 | 0.0765 | 0.0765 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.