Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0072 | 0.094 | 0.0573 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0072 | 0.094 | 0.0573 |
Onchocerca volvulus | 0.0072 | 0.094 | 0.1881 | |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0072 | 0.094 | 0.0573 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.094 | 0.0573 |
Brugia malayi | Type I phosphodiesterase / nucleotide pyrophosphatase family protein | 0.0072 | 0.094 | 0.094 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.094 | 0.0573 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.0156 | 0.4998 | 0.4796 |
Brugia malayi | Thrombospondin type 1 domain containing protein | 0.0156 | 0.4998 | 0.4998 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0072 | 0.094 | 0.0573 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0072 | 0.094 | 0.1881 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.026 | 1 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0072 | 0.094 | 0.0573 |
Loa Loa (eye worm) | hypothetical protein | 0.026 | 1 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0072 | 0.094 | 0.0573 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0072 | 0.094 | 0.1881 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0072 | 0.094 | 0.1881 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.026 | 1 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0072 | 0.094 | 0.0573 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0072 | 0.094 | 0.0573 |
Schistosoma mansoni | hypothetical protein | 0.0156 | 0.4998 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.094 | 0.0573 |
Onchocerca volvulus | 0.0156 | 0.4998 | 1 | |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0072 | 0.094 | 0.1881 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0072 | 0.094 | 0.0573 |
Onchocerca volvulus | 0.0072 | 0.094 | 0.1881 | |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0072 | 0.094 | 0.0573 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0072 | 0.094 | 0.0573 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 57 % | Bronchorelaxing effect on LTD4-contracted small human lung airways assessed as remaining contraction at 10 uM after 1.5 hrs relative to control | ChEMBL. | 18065228 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.