Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0198 | 0.2443 | 0.4812 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0333 | 0.0804 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0281 | 0.0667 |
Onchocerca volvulus | 0.0033 | 0.0333 | 1 | |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0281 | 1 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0212 | 1 |
Echinococcus multilocularis | snurportin 1 | 0.0304 | 0.3794 | 0.3789 |
Echinococcus granulosus | dnaJ subfamily B | 0.0405 | 0.5068 | 1 |
Echinococcus granulosus | snurportin 1 | 0.0304 | 0.3794 | 0.7482 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0405 | 0.5068 | 0.5064 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0304 | 0.3794 | 1 |
Onchocerca volvulus | 0.0033 | 0.0333 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0405 | 0.5068 | 1 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0017 | 0.014 | 0.1211 |
Toxoplasma gondii | 1,3-beta-glucan synthase component protein | 0.0458 | 0.575 | 1 |
Brugia malayi | hypothetical protein | 0.0016 | 0.012 | 0.0997 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.03 | 0.0293 |
Echinococcus granulosus | lamin | 0.0033 | 0.0333 | 0.0642 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.0603 | 0.0674 |
Schistosoma mansoni | hypothetical protein | 0.0304 | 0.3794 | 0.7482 |
Plasmodium falciparum | importin beta, putative | 0.0029 | 0.0281 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0033 | 0.0333 | 0.3299 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0212 | 1 |
Schistosoma mansoni | lamin | 0.0033 | 0.0333 | 0.0642 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0212 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0033 | 0.0333 | 0.0325 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0231 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.028 | 0.0663 |
Echinococcus multilocularis | musashi | 0.0033 | 0.0333 | 0.0325 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0118 | 0.0234 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0029 | 0.0281 | 0.009 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.003 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0111 | 0.0214 |
Echinococcus granulosus | importin subunit beta 1 | 0.0029 | 0.0281 | 0.054 |
Brugia malayi | Importin beta-1 subunit | 0.0029 | 0.0281 | 0.274 |
Schistosoma mansoni | importin beta-1 | 0.0029 | 0.0281 | 0.054 |
Brugia malayi | RNA, U transporter 1 | 0.0081 | 0.095 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0231 | 1 |
Plasmodium vivax | importin-beta 2, putative | 0.0029 | 0.0281 | 1 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0011 | 0.0059 | 0.0051 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0016 | 0.0118 | 0.011 |
Loa Loa (eye worm) | intermediate filament protein | 0.0033 | 0.0333 | 0.0804 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0325 | 0.0784 |
Echinococcus multilocularis | geminin | 0.0198 | 0.2443 | 0.2437 |
Brugia malayi | intermediate filament protein | 0.0033 | 0.0333 | 0.3299 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0011 | 0.0059 | 0.01 |
Schistosoma mansoni | intermediate filament proteins | 0.0033 | 0.0333 | 0.0642 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.028 | 0.2724 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0111 | 0.0214 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0281 | 1 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0017 | 0.014 | 0.0293 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.028 | 0.0537 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0212 | 0.5 |
Echinococcus granulosus | geminin | 0.0198 | 0.2443 | 0.4812 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0059 | 0.01 |
Schistosoma mansoni | lamin | 0.0033 | 0.0333 | 0.0642 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.003 | 0.0044 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.03 | 0.0578 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0231 | 0.0535 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.0685 | 0.1338 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.03 | 0.0578 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.03 | 0.0578 |
Echinococcus granulosus | intermediate filament protein | 0.0033 | 0.0333 | 0.0642 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0033 | 0.0333 | 0.0804 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0016 | 0.0118 | 0.0218 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0029 | 0.0281 | 0.0273 |
Echinococcus multilocularis | lamin | 0.0033 | 0.0333 | 0.0325 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0231 | 1 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0231 | 0.2201 |
Schistosoma mansoni | hypothetical protein | 0.0198 | 0.2443 | 0.4812 |
Echinococcus granulosus | lamin dm0 | 0.0033 | 0.0333 | 0.0642 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
29 literature references were collected for this gene.