Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Importin beta-1 subunit | 0.0029 | 0.0281 | 0.274 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0231 | 1 |
Schistosoma mansoni | importin beta-1 | 0.0029 | 0.0281 | 0.054 |
Brugia malayi | RNA, U transporter 1 | 0.0081 | 0.095 | 1 |
Plasmodium vivax | importin-beta 2, putative | 0.0029 | 0.0281 | 1 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0016 | 0.0118 | 0.011 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0011 | 0.0059 | 0.0051 |
Loa Loa (eye worm) | intermediate filament protein | 0.0033 | 0.0333 | 0.0804 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0325 | 0.0784 |
Echinococcus multilocularis | geminin | 0.0198 | 0.2443 | 0.2437 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0011 | 0.0059 | 0.01 |
Brugia malayi | intermediate filament protein | 0.0033 | 0.0333 | 0.3299 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.028 | 0.2724 |
Schistosoma mansoni | intermediate filament proteins | 0.0033 | 0.0333 | 0.0642 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0111 | 0.0214 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.028 | 0.0537 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0212 | 0.5 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0017 | 0.014 | 0.0293 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0281 | 1 |
Schistosoma mansoni | lamin | 0.0033 | 0.0333 | 0.0642 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0059 | 0.01 |
Echinococcus granulosus | geminin | 0.0198 | 0.2443 | 0.4812 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.003 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0231 | 0.0535 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.03 | 0.0578 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.03 | 0.0578 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.03 | 0.0578 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.0685 | 0.1338 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0033 | 0.0333 | 0.0804 |
Echinococcus granulosus | intermediate filament protein | 0.0033 | 0.0333 | 0.0642 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0016 | 0.0118 | 0.0218 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0029 | 0.0281 | 0.0273 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0231 | 0.2201 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0231 | 1 |
Echinococcus multilocularis | lamin | 0.0033 | 0.0333 | 0.0325 |
Schistosoma mansoni | hypothetical protein | 0.0198 | 0.2443 | 0.4812 |
Echinococcus granulosus | lamin dm0 | 0.0033 | 0.0333 | 0.0642 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0333 | 0.0804 |
Schistosoma mansoni | hypothetical protein | 0.0198 | 0.2443 | 0.4812 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0029 | 0.0281 | 1 |
Onchocerca volvulus | 0.0033 | 0.0333 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0281 | 0.0667 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0212 | 1 |
Echinococcus multilocularis | snurportin 1 | 0.0304 | 0.3794 | 0.3789 |
Echinococcus granulosus | dnaJ subfamily B | 0.0405 | 0.5068 | 1 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0405 | 0.5068 | 0.5064 |
Echinococcus granulosus | snurportin 1 | 0.0304 | 0.3794 | 0.7482 |
Onchocerca volvulus | 0.0033 | 0.0333 | 1 | |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0304 | 0.3794 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0405 | 0.5068 | 1 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0017 | 0.014 | 0.1211 |
Toxoplasma gondii | 1,3-beta-glucan synthase component protein | 0.0458 | 0.575 | 1 |
Brugia malayi | hypothetical protein | 0.0016 | 0.012 | 0.0997 |
Echinococcus granulosus | lamin | 0.0033 | 0.0333 | 0.0642 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.03 | 0.0293 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.0603 | 0.0674 |
Plasmodium falciparum | importin beta, putative | 0.0029 | 0.0281 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0304 | 0.3794 | 0.7482 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0212 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0033 | 0.0333 | 0.3299 |
Schistosoma mansoni | lamin | 0.0033 | 0.0333 | 0.0642 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0212 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0033 | 0.0333 | 0.0325 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0231 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.028 | 0.0663 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0118 | 0.0234 |
Echinococcus multilocularis | musashi | 0.0033 | 0.0333 | 0.0325 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0029 | 0.0281 | 0.009 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.003 | 0.0022 |
Echinococcus granulosus | importin subunit beta 1 | 0.0029 | 0.0281 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0111 | 0.0214 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
29 literature references were collected for this gene.