Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.026 | 0.7871 | 0.6715 |
Leishmania major | glucose-6-phosphate 1-dehydrogenase, putative | 0.0304 | 1 | 1 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.017 | 0.352 | 0.352 |
Trypanosoma cruzi | glucose-6-phosphate 1-dehydrogenase, putative | 0.0304 | 1 | 1 |
Trypanosoma cruzi | glucose-6-phosphate 1-dehydrogenase, putative | 0.0101 | 0.0142 | 0.0142 |
Trichomonas vaginalis | 6-phosphogluconolactonase, putative | 0.0304 | 1 | 0.5 |
Echinococcus granulosus | sterol O acyltransferase 1 | 0.026 | 0.7871 | 0.6715 |
Trichomonas vaginalis | glucosamine-6-phosphate isomerase, putative | 0.0304 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) | 0.0105 | 0.0371 | 0.5 |
Trypanosoma brucei | glucose-6-phosphate 1-dehydrogenase | 0.0304 | 1 | 1 |
Loa Loa (eye worm) | glucose-6-phosphate dehydrogenase | 0.0304 | 1 | 1 |
Schistosoma mansoni | glucose-6-phosphate 1-dehydrogenase | 0.0304 | 1 | 1 |
Echinococcus multilocularis | sterol O acyltransferase 1 | 0.026 | 0.7871 | 0.6715 |
Plasmodium vivax | glucose-6-phosphate 1-dehydrogenase, putative | 0.0304 | 1 | 0.5 |
Toxoplasma gondii | glucose-6-phosphate 1-dehydrogenase | 0.0304 | 1 | 1 |
Giardia lamblia | Glucose-6-phosphate 1-dehydrogenase | 0.0304 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0235 | 0.6639 | 0.4813 |
Echinococcus granulosus | glucose 6 phosphate 1 dehydrogenase | 0.0304 | 1 | 1 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.017 | 0.352 | 0.352 |
Plasmodium falciparum | glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | 0.0304 | 1 | 0.5 |
Schistosoma mansoni | sterol O-acyltransferase 1 | 0.026 | 0.7871 | 0.6715 |
Treponema pallidum | glucose-6-phosphate 1-dehydrogenase | 0.0304 | 1 | 0.5 |
Mycobacterium ulcerans | glucose-6-phosphate 1-dehydrogenase | 0.0304 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0293 | 0.944 | 0.9136 |
Trichomonas vaginalis | glucosamine-6-phosphate isomerase, putative | 0.0304 | 1 | 0.5 |
Echinococcus multilocularis | glucose 6 phosphate 1 dehydrogenase | 0.0304 | 1 | 1 |
Chlamydia trachomatis | glucose-6-phosphate 1-dehydrogenase | 0.0304 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.