Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | G protein coupled receptor kinase 1 | 0.0081 | 0.3085 | 0.3085 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0066 | 0.239 | 0.239 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.009 | 0.3532 | 0.3532 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.7639 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1274 | 0.1434 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0332 | 0.0374 |
Echinococcus multilocularis | aminopeptidase N | 0.0225 | 1 | 1 |
Echinococcus granulosus | geminin | 0.0176 | 0.7639 | 0.7639 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.091 | 0.1191 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.8884 | 1 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0453 | 0.0453 |
Loa Loa (eye worm) | aminopeptidase N | 0.0066 | 0.239 | 0.2691 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0066 | 0.239 | 1 |
Echinococcus granulosus | aminopeptidase N | 0.0225 | 1 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0023 | 0.0332 | 0.0332 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0066 | 0.239 | 0.239 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0453 | 0.051 |
Brugia malayi | Peptidase family M1 containing protein | 0.0023 | 0.0332 | 0.0332 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0066 | 0.239 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0453 | 0.0589 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0066 | 0.239 | 1 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0182 | 0.7942 | 0.8939 |
Brugia malayi | hypothetical protein | 0.0066 | 0.239 | 0.239 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0066 | 0.239 | 1 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0066 | 0.239 | 0.3129 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.0023 | 0.0332 | 0.0435 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.6826 | 0.7683 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0066 | 0.239 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.1694 | 0.1907 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0023 | 0.0332 | 0.0435 |
Entamoeba histolytica | aminopeptidase, putative | 0.0066 | 0.239 | 0.5 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0023 | 0.0332 | 0.0374 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0066 | 0.239 | 0.239 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.1694 | 0.1694 |
Schistosoma mansoni | family M1 non-peptidase homologue (M01 family) | 0.0043 | 0.1274 | 0.1668 |
Brugia malayi | TATA binding protein associated factor | 0.0023 | 0.0332 | 0.0332 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0332 | 0.0332 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0066 | 0.239 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0043 | 0.1274 | 0.1274 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1274 | 0.1434 |
Echinococcus granulosus | G protein coupled receptor kinase 1 | 0.0081 | 0.3085 | 0.3085 |
Echinococcus multilocularis | geminin | 0.0176 | 0.7639 | 0.7639 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0066 | 0.239 | 0.239 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0453 | 0.0589 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0453 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0066 | 0.239 | 0.239 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.091 | 0.1024 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0453 | 0.0589 |
Schistosoma mansoni | serine/threonine protein kinase | 0.009 | 0.3532 | 0.4623 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.7639 | 1 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0043 | 0.1274 | 0.4578 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0453 | 1 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0066 | 0.239 | 1 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0066 | 0.239 | 0.239 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0332 | 0.0374 |
Brugia malayi | Peptidase family M1 containing protein | 0.0066 | 0.239 | 0.239 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0066 | 0.239 | 0.239 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0066 | 0.239 | 0.3129 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0453 | 1 |
Onchocerca volvulus | 0.0225 | 1 | 1 | |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0066 | 0.239 | 1 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.009 | 0.3532 | 0.3975 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0066 | 0.239 | 1 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.0023 | 0.0332 | 0.0332 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.1694 | 0.1694 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0066 | 0.239 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1694 | 0.1907 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0453 | 0.0589 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0332 | 0.0374 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.091 | 0.091 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0066 | 0.239 | 0.239 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0023 | 0.0332 | 0.0332 |
Onchocerca volvulus | 0.0066 | 0.239 | 0.2129 | |
Brugia malayi | hypothetical protein | 0.0017 | 0.0015 | 0.0015 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0453 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0066 | 0.239 | 0.239 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.0023 | 0.0332 | 0.0374 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.009 | 0.3532 | 0.3532 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0066 | 0.239 | 0.239 |
Schistosoma mansoni | serine/threonine protein kinase | 0.009 | 0.3532 | 0.4623 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0023 | 0.0332 | 0.0435 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0066 | 0.239 | 1 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.0023 | 0.0332 | 0.0332 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.