Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Sugar transporter family protein | 0.0313 | 0.1184 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0313 | 0.1184 | 0.5 |
Loa Loa (eye worm) | sugar transporter | 0.0313 | 0.1184 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0313 | 0.1184 | 1 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0313 | 0.1184 | 1 |
Schistosoma mansoni | glucose transport protein | 0.0313 | 0.1184 | 0.5 |
Leishmania major | glucose transporter, lmgt2 | 0.0097 | 0.0201 | 0.5 |
Plasmodium falciparum | hexose transporter | 0.0313 | 0.1184 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0313 | 0.1184 | 1 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0313 | 0.1184 | 1 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0313 | 0.1184 | 1 |
Trypanosoma cruzi | hexose transporter, putative | 0.0097 | 0.0201 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0313 | 0.1184 | 0.5 |
Leishmania major | glucose transporter, lmgt3 | 0.0097 | 0.0201 | 0.5 |
Leishmania major | glucose transporter, lmgt1 | 0.0097 | 0.0201 | 0.5 |
Trypanosoma brucei | adenosine transporter, putative | 0.225 | 1 | 1 |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.0313 | 0.1184 | 1 |
Trypanosoma cruzi | hexose transporter, putative | 0.0097 | 0.0201 | 1 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0313 | 0.1184 | 1 |
Trypanosoma cruzi | hexose transporter, putative | 0.0097 | 0.0201 | 1 |
Schistosoma mansoni | glucose transport protein | 0.0313 | 0.1184 | 0.5 |
Leishmania major | glucose transporter/membrane transporter D2, putative | 0.0097 | 0.0201 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0313 | 0.1184 | 1 |
Plasmodium vivax | hexose transporter | 0.0313 | 0.1184 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0313 | 0.1184 | 1 |
Trypanosoma cruzi | hexose transporter | 0.0097 | 0.0201 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.