Detailed information for compound 566053

Basic information

Technical information
  • TDR Targets ID: 566053
  • Name: potassium silver dicyanide
  • MW: 199.001 | Formula: C2AgKN2
  • H donors: 0 H acceptors: 0 LogP: 0.13 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: [C-]#N.[C-]#N.[K+].[Ag+]
  • InChi: 1S/2CN.Ag.K/c2*1-2;;/q2*-1;2*+1
  • InChiKey: HKSGQTYSSZOJOA-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • potassium silver cyanide
  • 2541-67-5
  • 506-61-6
  • 10201_RIEDEL
  • Argentate(1-), bis(cyano-C)-, potassium
  • Argentate(1-), bis(cyano-C)-, potassium (9CI)
  • Argentate(1-), bis(cyano-kappaC)-, potassium
  • Argentate(1-), dicyano-, potassium
  • EINECS 208-047-0
  • HSDB 6053
  • Kyanostribrnan draselny [Czech]
  • Potassium argentocyanide
  • Potassium bis(cyano-C)argentate(1-)
  • Potassium dicyanoargentate
  • Potassium dicyanoargentate (KAg(CN)2)
  • Potassium dicyanoargentate(1-)
  • Potassium silver cyanide (KAg(CN)2)
  • RCRA waste no. P099
  • RCRA waste number P099
  • S 900
  • Silver potassium cyanide
  • 379166_ALDRICH
  • Potassium silver(I) cyanide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens jun proto-oncogene Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus jun protein Get druggable targets OG5_131442 All targets in OG5_131442
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor Get druggable targets OG5_131442 All targets in OG5_131442
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131442 All targets in OG5_131442
Brugia malayi bZIP transcription factor family protein Get druggable targets OG5_131442 All targets in OG5_131442
Echinococcus multilocularis jun protein Get druggable targets OG5_131442 All targets in OG5_131442
Echinococcus granulosus Basic leucine zipper bZIP transcription factor Get druggable targets OG5_131442 All targets in OG5_131442

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.1096 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.1197 0.1197
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.1197 0.1197
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.001 0.006 0.006
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0043 0.0043
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0043 0.0061
Schistosoma mansoni jun-related protein 0.0082 0.2479 0.2479
Plasmodium falciparum importin beta, putative 0.0029 0.0673 0.453
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0015 0.0222 0.0222
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.1197 0.1197
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0043 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0043 0.0061
Echinococcus multilocularis geminin 0.0164 0.5223 0.5223
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0043 0.0043
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0418 0.0592
Schistosoma mansoni ran 0.0021 0.0418 0.0418
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0043 0.0061
Echinococcus multilocularis neuropeptide receptor 0.0207 0.6684 0.6684
Loa Loa (eye worm) hypothetical protein 0.0015 0.0222 0.0222
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0673 0.0673
Echinococcus granulosus ETS transcription factor Elf 5 0.001 0.006 0.006
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.049 0.1066
Echinococcus multilocularis protein C ets 2 0.001 0.006 0.006
Onchocerca volvulus 0.001 0.0043 0.0076
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.098 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0043 0.0061
Schistosoma mansoni gabp alpha 0.0072 0.213 0.213
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0817 0.1158
Echinococcus multilocularis ETS transcription factor Elf 5 0.001 0.006 0.006
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0043 0.0043
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0222 0.0222
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.1096 1
Brugia malayi ecdysteroid receptor 0.001 0.0043 0.0061
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0043
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0043 0.0043
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.001 0.006 0.006
Brugia malayi Ets-domain containing protein 0.0072 0.213 0.3017
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.049 0.1066
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0015 0.0222 0.0222
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.006 0.006
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0043 0.0043
Echinococcus multilocularis jun protein 0.0101 0.3118 0.3118
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1197 0.1197
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0222 0.0314
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0043 0.0043
Echinococcus granulosus geminin 0.0164 0.5223 0.5223
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0043 0.0043
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.098 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1197 0.1197
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0043 0.0061
Entamoeba histolytica hypothetical protein 0.0043 0.1169 1
Schistosoma mansoni thyroid hormone receptor 0.001 0.0043 0.0043
Echinococcus granulosus importin subunit beta 1 0.0029 0.0673 0.0673
Loa Loa (eye worm) hypothetical protein 0.001 0.006 0.006
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.049 1
Entamoeba histolytica hypothetical protein 0.0023 0.049 0.0961
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0176 0.5628 1
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0418 0.0418
Schistosoma mansoni hypothetical protein 0.0164 0.5223 0.5223
Echinococcus granulosus jun protein 0.0101 0.3118 0.3118
Schistosoma mansoni ran 0.0021 0.0418 0.0418
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0043 0.0061
Schistosoma mansoni hypothetical protein 0.0082 0.2479 0.2479
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0222 0.0222
Brugia malayi DNA-binding protein D-ETS-3 0.001 0.006 0.0085
Echinococcus granulosus ETS domain containing protein Elk 1 0.001 0.006 0.006
Echinococcus granulosus protein C ets 2 0.001 0.006 0.006
Schistosoma mansoni thyroid hormone receptor 0.001 0.0043 0.0043
Echinococcus multilocularis ets variant gene 4 0.001 0.006 0.006
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.1197 0.1197
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.098 0.7481
Schistosoma mansoni coup transcription factor 0.001 0.0043 0.0043
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0222 0.0222
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.001 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0043
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.1197 0.1696
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0043 0.0061
Plasmodium vivax importin-beta 2, putative 0.0029 0.0673 0.3757
Schistosoma mansoni hypothetical protein 0.001 0.006 0.006
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0673 1
Echinococcus multilocularis ewsr:fli fusion protein type 0.001 0.006 0.006
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0101 0.3118 0.3118
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0043 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0043 0.0061
Echinococcus multilocularis GPCR, family 2 0.0015 0.0222 0.0222
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0043 0.0076
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.213 0.213
Echinococcus multilocularis ETS domain containing protein Elk 1 0.001 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0176 0.5628 0.5628
Schistosoma mansoni hypothetical protein 0.0015 0.0222 0.0222
Loa Loa (eye worm) hypothetical protein 0.001 0.006 0.006
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0043 0.0043
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0222 0.0222
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0043 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0043 0.0043
Echinococcus granulosus ewsr:fli fusion protein type 0.001 0.006 0.006
Brugia malayi Ets-domain containing protein 0.0072 0.213 0.3017
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0418 0.0418
Echinococcus granulosus ETS transcription factor Elf 1 0.001 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0043
Brugia malayi N-terminal motif family protein 0.0176 0.5628 0.7973
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0015 0.0222 0.0222
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0673 0.614
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.006 0.006
Echinococcus granulosus FTZ F1 alpha 0.001 0.0043 0.0043
Brugia malayi nuclear receptor NHR-88 0.001 0.0043 0.0061
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0043 0.0043
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0043 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0043 0.0043
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0418 0.3817
Loa Loa (eye worm) D-ets-2 protein 0.001 0.006 0.006
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0043 0.0043
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1197 0.1197
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0043 0.0043
Schistosoma mansoni elf1 0.001 0.006 0.006
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0043 0.0043
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.4293 0.4293
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0043
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0146 0.4625 0.4625
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0043 0.0043
Brugia malayi steroid hormone receptor 0.001 0.0043 0.0061
Echinococcus multilocularis G protein coupled receptor 139 0.0207 0.6684 0.6684
Brugia malayi bZIP transcription factor family protein 0.0101 0.3118 0.4417
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.1197 0.1197
Loa Loa (eye worm) hypothetical protein 0.0029 0.0673 0.0673
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.006 0.006
Leishmania major importin beta-1 subunit, putative 0.0023 0.049 1
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0043 0.0076
Onchocerca volvulus 0.0146 0.4625 0.8218
Schistosoma mansoni hypothetical protein 0.0306 1 1
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.014 0.4425 0.4425
Brugia malayi hypothetical protein 0.008 0.2386 0.338
Trichomonas vaginalis importin beta-1, putative 0.0023 0.049 0.1066
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.1331 0.1331
Schistosoma mansoni ets 0.001 0.006 0.006
Schistosoma mansoni hypothetical protein 0.0043 0.1169 0.1169
Loa Loa (eye worm) hypothetical protein 0.0099 0.3024 0.3024
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.006 0.006
Schistosoma mansoni importin beta-1 0.0029 0.0673 0.0673
Schistosoma mansoni nuclear hormone receptor 0.001 0.0043 0.0043
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0222 0.0222
Entamoeba histolytica hypothetical protein 0.0043 0.1169 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.1331 0.1885
Schistosoma mansoni ets-related 0.0219 0.7059 0.7059
Onchocerca volvulus 0.008 0.2386 0.4239
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0673 1
Schistosoma mansoni hypothetical protein 0.0164 0.5223 0.5223
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0043 0.0043
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.001 0.006 0.006
Brugia malayi nuclear hormone receptor 0.001 0.0043 0.0061
Echinococcus granulosus neuropeptide receptor 0.0207 0.6684 0.6684
Echinococcus granulosus GPCR family 2 0.0015 0.0222 0.0222
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0043 0.0061
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0043 0.0061
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0043 0.0043
Schistosoma mansoni neuropeptide receptor 0.0207 0.6684 0.6684
Echinococcus multilocularis snurportin 1 0.0306 1 1
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0043 0.0043
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.1169 0.1169
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0043 0.0043
Loa Loa (eye worm) fli-1 protein 0.0219 0.7059 0.7059
Brugia malayi RNA, U transporter 1 0.0082 0.245 0.3471
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0222 0.0314
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0043
Brugia malayi transcription factor E74 isoform 0.001 0.006 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0043 0.0061
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.1096 1
Schistosoma mansoni hypothetical protein 0.0033 0.0817 0.0817
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0043 0.0061
Loa Loa (eye worm) ets-domain-containing protein 0.001 0.006 0.006
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0418 0.0418
Loa Loa (eye worm) hypothetical protein 0.0033 0.0817 0.0817
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0043 0.0043
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0062 0.1779 0.1779
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0043 0.0043
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0043 0.0043
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0101 0.3118 0.3118
Brugia malayi Importin beta-1 subunit 0.0029 0.0673 0.0953
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0043
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.213 0.213
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.1096 1
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.014 0.4425 0.4425
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0043
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0043 0.0076
Loa Loa (eye worm) acetyltransferase 0.014 0.4425 0.4425
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.213 0.213
Brugia malayi hypothetical protein 0.0043 0.1169 0.1656
Echinococcus multilocularis ETS transcription factor Elf 1 0.001 0.006 0.006
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0306 1 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.1331 0.1331
Brugia malayi acetyltransferase, GNAT family protein 0.014 0.4425 0.6268
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.1096 1
Schistosoma mansoni ets-related 0.001 0.006 0.006
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.1331 0.1885
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0043 0.0061
Brugia malayi hypothetical protein 0.0146 0.4625 0.6552
Entamoeba histolytica hypothetical protein 0.0043 0.1169 1
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.1169 0.1169
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.1169 0.1169
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0043 0.0061
Entamoeba histolytica hypothetical protein 0.0043 0.1169 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0043 0.0043
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.1096 0.1096
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0043 0.0061
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0043 0.0043
Brugia malayi Ets-domain containing protein 0.001 0.006 0.0085
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0043 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0043 0.0061
Brugia malayi Fli-1 protein 0.0219 0.7059 1

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 9.6885 uM PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.5081 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 24.5593 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the NFkB signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 27.5559 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 34.6909 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 49.0022 uM PubChem BioAssay: Tox21. qHTS assay for small molecule activators of the heat shock response signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 54.4827 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 54.9813 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 54.9813 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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