Detailed information for compound 566053

Basic information

Technical information
  • TDR Targets ID: 566053
  • Name: potassium silver dicyanide
  • MW: 199.001 | Formula: C2AgKN2
  • H donors: 0 H acceptors: 0 LogP: 0.13 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: [C-]#N.[C-]#N.[K+].[Ag+]
  • InChi: 1S/2CN.Ag.K/c2*1-2;;/q2*-1;2*+1
  • InChiKey: HKSGQTYSSZOJOA-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • potassium silver cyanide
  • 2541-67-5
  • 506-61-6
  • 10201_RIEDEL
  • Argentate(1-), bis(cyano-C)-, potassium
  • Argentate(1-), bis(cyano-C)-, potassium (9CI)
  • Argentate(1-), bis(cyano-kappaC)-, potassium
  • Argentate(1-), dicyano-, potassium
  • EINECS 208-047-0
  • HSDB 6053
  • Kyanostribrnan draselny [Czech]
  • Potassium argentocyanide
  • Potassium bis(cyano-C)argentate(1-)
  • Potassium dicyanoargentate
  • Potassium dicyanoargentate (KAg(CN)2)
  • Potassium dicyanoargentate(1-)
  • Potassium silver cyanide (KAg(CN)2)
  • RCRA waste no. P099
  • RCRA waste number P099
  • S 900
  • Silver potassium cyanide
  • 379166_ALDRICH
  • Potassium silver(I) cyanide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens jun proto-oncogene Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus Basic leucine zipper bZIP transcription factor Get druggable targets OG5_131442 All targets in OG5_131442
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor Get druggable targets OG5_131442 All targets in OG5_131442
Echinococcus multilocularis jun protein Get druggable targets OG5_131442 All targets in OG5_131442
Echinococcus granulosus jun protein Get druggable targets OG5_131442 All targets in OG5_131442
Brugia malayi bZIP transcription factor family protein Get druggable targets OG5_131442 All targets in OG5_131442
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131442 All targets in OG5_131442

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0673 1
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0817 0.1158
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.4293 0.4293
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0176 0.5628 1
Echinococcus multilocularis ets variant gene 4 0.001 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0043
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0043 0.0043
Echinococcus multilocularis neuropeptide receptor 0.0207 0.6684 0.6684
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0043 0.0043
Loa Loa (eye worm) ets-domain-containing protein 0.001 0.006 0.006
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0043 0.0043
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0043 0.0043
Entamoeba histolytica hypothetical protein 0.0043 0.1169 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.1096 1
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0222 0.0314
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0043 0.0061
Loa Loa (eye worm) hypothetical protein 0.0062 0.1779 0.1779
Echinococcus multilocularis G protein coupled receptor 139 0.0207 0.6684 0.6684
Echinococcus multilocularis ETS transcription factor Elf 1 0.001 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0029 0.0673 0.0673
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0043 0.0076
Echinococcus multilocularis protein C ets 2 0.001 0.006 0.006
Schistosoma mansoni thyroid hormone receptor 0.001 0.0043 0.0043
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0043 0.0043
Schistosoma mansoni neuropeptide receptor 0.0207 0.6684 0.6684
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0043 0.0043
Schistosoma mansoni nuclear hormone receptor 0.001 0.0043 0.0043
Echinococcus granulosus ETS transcription factor Elf 1 0.001 0.006 0.006
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.001 0.006 0.006
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0043 0.0043
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0222 0.0222
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.049 1
Schistosoma mansoni hypothetical protein 0.0306 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1197 0.1197
Schistosoma mansoni hypothetical protein 0.0015 0.0222 0.0222
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.098 1
Echinococcus granulosus ETS domain containing protein Elk 1 0.001 0.006 0.006
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0043 0.0043
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0673 0.0673
Schistosoma mansoni ets 0.001 0.006 0.006
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0072 0.213 0.213
Loa Loa (eye worm) hypothetical protein 0.001 0.006 0.006
Brugia malayi N-terminal motif family protein 0.0176 0.5628 0.7973
Echinococcus multilocularis jun protein 0.0101 0.3118 0.3118
Schistosoma mansoni ran 0.0021 0.0418 0.0418
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.001 0.006 0.006
Brugia malayi Ets-domain containing protein 0.001 0.006 0.0085
Schistosoma mansoni coup transcription factor 0.001 0.0043 0.0043
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0043 0.0043
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.1169 0.1169
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0222 0.0314
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0043 0.0043
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0222 0.0222
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0043 0.0043
Trichomonas vaginalis importin beta-1, putative 0.0023 0.049 0.1066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0043 0.0043
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.049 0.1066
Loa Loa (eye worm) hypothetical protein 0.0146 0.4625 0.4625
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.014 0.4425 0.4425
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0043 0.0043
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0673 0.614
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1197 0.1197
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0048 0.1331 0.1331
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.1096 1
Echinococcus granulosus protein C ets 2 0.001 0.006 0.006
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.001 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0043
Echinococcus multilocularis ETS transcription factor Elf 5 0.001 0.006 0.006
Schistosoma mansoni hypothetical protein 0.0082 0.2479 0.2479
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0043 0.0076
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.1331 0.1885
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0043 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0043 0.0043
Brugia malayi hypothetical protein 0.008 0.2386 0.338
Plasmodium vivax importin-beta 2, putative 0.0029 0.0673 0.3757
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0044 0.1197 0.1696
Echinococcus granulosus FTZ F1 alpha 0.001 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0099 0.3024 0.3024
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0043 0.0061
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.1096 1
Brugia malayi ecdysteroid receptor 0.001 0.0043 0.0061
Brugia malayi DNA-binding protein D-ETS-3 0.001 0.006 0.0085
Schistosoma mansoni ran 0.0021 0.0418 0.0418
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0043 0.0061
Plasmodium falciparum importin beta, putative 0.0029 0.0673 0.453
Schistosoma mansoni hypothetical protein 0.0015 0.0222 0.0222
Loa Loa (eye worm) hypothetical protein 0.0015 0.0222 0.0222
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0043 0.0043
Schistosoma mansoni ets-related 0.001 0.006 0.006
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0222 0.0222
Echinococcus granulosus geminin 0.0164 0.5223 0.5223
Echinococcus multilocularis ewsr:fli fusion protein type 0.001 0.006 0.006
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.1096 1
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.014 0.4425 0.4425
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.006 0.006
Schistosoma mansoni hypothetical protein 0.001 0.006 0.006
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.1197 0.1197
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0043 0.0043
Brugia malayi acetyltransferase, GNAT family protein 0.014 0.4425 0.6268
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0043
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0043 0.0043
Brugia malayi Ets-domain containing protein 0.0072 0.213 0.3017
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.006 0.006
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0043 0.0043
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0418 0.0418
Echinococcus multilocularis GA binding protein alpha chain 0.0072 0.213 0.213
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0418 0.0418
Entamoeba histolytica hypothetical protein 0.0043 0.1169 1
Loa Loa (eye worm) acetyltransferase 0.014 0.4425 0.4425
Brugia malayi nuclear receptor NHR-88 0.001 0.0043 0.0061
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0222 0.0222
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0101 0.3118 0.3118
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0043 0.0061
Echinococcus multilocularis GPCR, family 2 0.0015 0.0222 0.0222
Loa Loa (eye worm) hypothetical protein 0.001 0.006 0.006
Entamoeba histolytica hypothetical protein 0.0043 0.1169 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0043 0.0061
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0043 0.0043
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.006 0.006
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.1197 0.1197
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0101 0.3118 0.3118
Echinococcus granulosus GPCR family 2 0.0015 0.0222 0.0222
Schistosoma mansoni hypothetical protein 0.0043 0.1169 0.1169
Schistosoma mansoni elf1 0.001 0.006 0.006
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0043 0.0061
Onchocerca volvulus 0.001 0.0043 0.0076
Schistosoma mansoni hypothetical protein 0.0164 0.5223 0.5223
Loa Loa (eye worm) fli-1 protein 0.0219 0.7059 0.7059
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.098 0.7481
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.1096 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0044 0.1197 0.1197
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0044 0.1197 0.1197
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0044 0.1197 0.1197
Brugia malayi hypothetical protein 0.0043 0.1169 0.1656
Loa Loa (eye worm) hypothetical protein 0.0176 0.5628 0.5628
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0043 0.0043
Entamoeba histolytica hypothetical protein 0.0023 0.049 0.0961
Entamoeba histolytica hypothetical protein 0.0043 0.1169 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0044 0.1197 0.1197
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.001 0.006 0.006
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.049 0.1066
Brugia malayi Ets-domain containing protein 0.0072 0.213 0.3017
Echinococcus granulosus jun protein 0.0101 0.3118 0.3118
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0043 0.0043
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0043 0.0043
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0043 0.0043
Schistosoma mansoni gabp alpha 0.0072 0.213 0.213
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.1169 0.1169
Brugia malayi Fli-1 protein 0.0219 0.7059 1
Echinococcus multilocularis geminin 0.0164 0.5223 0.5223
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0043 0.0061
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0043
Echinococcus granulosus neuropeptide receptor 0.0207 0.6684 0.6684
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0043 0.0043
Echinococcus multilocularis snurportin 1 0.0306 1 1
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.1169 0.1169
Echinococcus granulosus ewsr:fli fusion protein type 0.001 0.006 0.006
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0043 0.0061
Loa Loa (eye worm) hypothetical protein 0.0033 0.0817 0.0817
Brugia malayi nuclear hormone receptor 0.001 0.0043 0.0061
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0043 0.0043
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0222 0.0222
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0043 0.0061
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0043 0.0043
Echinococcus granulosus GA binding protein alpha chain 0.0072 0.213 0.213
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.1096 0.1096
Echinococcus granulosus importin subunit beta 1 0.0029 0.0673 0.0673
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0043 0.0043
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0043 0.0043
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.098 1
Onchocerca volvulus 0.008 0.2386 0.4239
Echinococcus granulosus ETS transcription factor Elf 5 0.001 0.006 0.006
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.1331 0.1331
Brugia malayi RNA, U transporter 1 0.0082 0.245 0.3471
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0418 0.3817
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0043 0.0061
Brugia malayi bZIP transcription factor family protein 0.0101 0.3118 0.4417
Schistosoma mansoni hypothetical protein 0.0164 0.5223 0.5223
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0418 0.0418
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0043 0.0043
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.1331 0.1885
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0043 0.0061
Schistosoma mansoni ets-related 0.0219 0.7059 0.7059
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0418 0.0592
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.006 0.006
Brugia malayi Importin beta-1 subunit 0.0029 0.0673 0.0953
Schistosoma mansoni thyroid hormone receptor 0.001 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0015 0.0222 0.0222
Onchocerca volvulus 0.0146 0.4625 0.8218
Loa Loa (eye worm) D-ets-2 protein 0.001 0.006 0.006
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0043 0.0061
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0043 0.0076
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0043 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0043 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0043 0.0061
Brugia malayi steroid hormone receptor 0.001 0.0043 0.0061
Brugia malayi hypothetical protein 0.0146 0.4625 0.6552
Echinococcus multilocularis ETS domain containing protein Elk 1 0.001 0.006 0.006
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0306 1 1
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0043 0.0061
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0043
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0673 1
Schistosoma mansoni hypothetical protein 0.0015 0.0222 0.0222
Leishmania major importin beta-1 subunit, putative 0.0023 0.049 1
Schistosoma mansoni importin beta-1 0.0029 0.0673 0.0673
Schistosoma mansoni hypothetical protein 0.0033 0.0817 0.0817
Brugia malayi transcription factor E74 isoform 0.001 0.006 0.0085
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0043 0.0061
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0043 0.0061
Schistosoma mansoni jun-related protein 0.0082 0.2479 0.2479
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.001 0.0043 0.0043

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 9.6885 uM PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 19.5081 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 24.5593 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the NFkB signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 27.5559 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 34.6909 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 49.0022 uM PubChem BioAssay: Tox21. qHTS assay for small molecule activators of the heat shock response signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 54.4827 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 54.9813 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 54.9813 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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