Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.1095 | 0.098 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.1095 | 0.1095 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0961 | 0.0961 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.2614 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.1095 | 0.5 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0961 | 0.2 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.2614 | 0.2614 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.1095 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.2614 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.2614 | 1 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.2614 | 0.2518 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.1095 | 0.5 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.2866 | 0.2866 |
Schistosoma mansoni | hypothetical protein | 0.017 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1192 | 0.3541 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.1028 | 0.0911 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.1095 | 0.5 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.1095 | 0.098 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0961 | 0.0843 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.2614 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0075 | 0.3653 | 1 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.2614 | 0.2518 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.1028 | 0.0911 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1351 | 0.4014 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.1095 | 0.5 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.2614 | 1 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0033 | 0.0835 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.1095 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.1187 | 0.2673 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.2625 | 0.2529 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0961 | 0.0961 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.2625 | 0.2529 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.1095 | 0.1095 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0128 | 0.0128 |
Echinococcus multilocularis | geminin | 0.017 | 1 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.2614 | 0.2614 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1479 | 0.4395 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.2614 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.1095 | 0.5 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.1095 | 1 |
Schistosoma mansoni | hypothetical protein | 0.017 | 1 | 1 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.1095 | 0.3255 |
Brugia malayi | Inositol-1 | 0.0037 | 0.1095 | 0.2401 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0961 | 0.0843 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.3366 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.