Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0033 | 0.2563 | 0.2563 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0033 | 0.2563 | 0.2563 |
Trypanosoma brucei | endonuclease G, putative | 0.002 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0071 | 1 | 1 |
Echinococcus multilocularis | ectonucleotide | 0.0028 | 0.1553 | 0.6061 |
Toxoplasma gondii | DNA/RNA non-specific endonuclease | 0.002 | 0 | 0.5 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.002 | 0 | 0.5 |
Onchocerca volvulus | 0.0071 | 1 | 1 | |
Brugia malayi | Type I phosphodiesterase / nucleotide pyrophosphatase family protein | 0.0033 | 0.2563 | 0.2563 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0028 | 0.1553 | 0.6061 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.2563 | 1 |
Trypanosoma brucei | endonuclease G, putative | 0.002 | 0 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.2563 | 1 |
Leishmania major | DNA/RNA non-specific endonuclease-like protein | 0.002 | 0 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.2563 | 1 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0033 | 0.2563 | 0.2563 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.2563 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.2563 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.2563 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.2563 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.2563 | 0.1195 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.0071 | 1 | 1 |
Trypanosoma cruzi | endonuclease G, putative | 0.002 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.2563 | 0.1195 |
Trypanosoma cruzi | endonuclease G, putative | 0.002 | 0 | 0.5 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0033 | 0.2563 | 0.2563 |
Echinococcus granulosus | ectonucleotide | 0.0028 | 0.1553 | 0.6061 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0028 | 0.1553 | 0.6061 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.2563 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.2563 | 1 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.002 | 0 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.2563 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.2563 | 0.1195 |
Trypanosoma brucei | endonuclease G, putative | 0.002 | 0 | 0.5 |
Leishmania major | endonuclease G, putative | 0.002 | 0 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0033 | 0.2563 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.