Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.3245 | 0.3245 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0008 | 0 | 0.5 |
Trichomonas vaginalis | ferritin, putative | 0.0008 | 0 | 0.5 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0453 | 0.0453 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.3245 | 0.3245 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0453 | 0.0453 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.257 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.3245 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0453 | 0.0453 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0453 | 0.0453 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.3245 | 0.3245 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.257 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.159 | 0.159 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0453 | 0.0453 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0453 | 0.0453 |
Echinococcus multilocularis | geminin | 0.0167 | 1 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0453 | 0.0453 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.159 | 0.5371 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.159 | 0.5371 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 1 | 1 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0008 | 0 | 0.5 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0453 | 0.0453 |
Plasmodium vivax | cyclin dependent kinase 7 (cdk7), putative | 0.0116 | 0.6793 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0008 | 0 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.257 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.3245 | 0.3245 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0453 | 0.0453 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.3245 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.3245 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.3245 | 0.5 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0453 | 0.0453 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.257 | 1 |
Plasmodium falciparum | MO15-related protein kinase | 0.0116 | 0.6793 | 0.5 |
Toxoplasma gondii | cell-cycle-associated protein kinase, putative | 0.0108 | 0.6311 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.3245 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.