TDR Targets

Basic information

Technical information

TDR Targets ID: 585474
Name: (E)-2-diazonio-1-ethoxy-3-[[(1S)-2-hydroxy-1- [[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo -phenyl]methyl]-2-oxo-ethyl]amino]-3-oxo-prop -1-en-1-olate
MW: 916.967 | Formula: C20H15I4N3O7
H donors: 3 H acceptors: 5 LogP: 7.4 Rotable bonds: 10
Rule of 5 violations (Lipinski): 2
SMILES: CCOC(=C(C(=O)N[C@H](C(=O)O)Cc1cc(I)c(c(c1)I)Oc1cc(I)c(c(c1)I)O)[N+]#N)[O-]
InChi: 1S/C20H15I4N3O7/c1-2-33-20(32)15(27-25)18(29)26-14(19(30)31)5-8-3-12(23)17(13(24)4-8)34-9-6-10(21)16(28)11(22)7-9/h3-4,6-7,14H,2,5H2,1H3,(H3-,26,28,29,30,31,32)/t14-/m0/s1
InChiKey: OHJXVNCMOVVLCQ-AWEZNQCLSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

(E)-2-diazonio-1-ethoxy-3-[[(1S)-2-hydroxy-1-[[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]methyl]-2-oxoethyl]amino]-3-oxo-1-propen-1-olate
(E)-2-diazonio-1-ethoxy-3-[[(2S)-1-hydroxy-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]-1-oxo-propan-2-yl]amino]-3-oxo-prop-1-en-1-olate
(E)-2-diazonio-1-ethoxy-3-[[(1S)-2-hydroxy-1-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-benzyl]-2-keto-ethyl]amino]-3-keto-prop-1-en-1-olate
(E)-2-diazonio-1-ethoxy-3-[[(2S)-1-hydroxy-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-1-oxopropan-2-yl]amino]-3-oxoprop-1-en-1-olate
N-(ethyl-2-diazomalonyl)thyroxine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus multilocularis	fmrfamide receptor	0.0042	0.2534	0.2505
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0039	0.5
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0042	0.2534	0.2505
Echinococcus granulosus	g protein coupled receptor	0.0042	0.2534	0.2505
Echinococcus multilocularis	neuropeptide receptor	0.0042	0.2534	0.2505
Onchocerca volvulus		0.0042	0.2534	1
Onchocerca volvulus		0.0042	0.2534	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0042	0.2534	0.2505
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0042	0.2534	1
Trichomonas vaginalis	alpha-L-fucosidase, putative	0.0018	0.0039	0.5
Echinococcus granulosus	tm gpcr rhodopsin	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Schistosoma mansoni	hypothetical protein	0.0042	0.2534	0.2505
Onchocerca volvulus		0.0042	0.2534	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.2534	0.2505
Echinococcus multilocularis	neuropeptide receptor A26	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Echinococcus multilocularis	neuropeptides capa receptor	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Schistosoma mansoni	biogenic amine receptor	0.0042	0.2534	0.2505
Echinococcus multilocularis	serotonin receptor	0.0042	0.2534	0.2505
Brugia malayi	Serotonin receptor	0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Brugia malayi	sulfakinin receptor protein	0.0042	0.2534	1
Echinococcus granulosus	biogenic amine 5HT receptor	0.0042	0.2534	0.2505
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.2534	0.2505
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0042	0.2534	0.2505
Onchocerca volvulus		0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0042	0.2534	0.2505
Onchocerca volvulus		0.0042	0.2534	1
Echinococcus multilocularis	fmrfamide receptor	0.0042	0.2534	0.2505
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0042	0.2534	0.2505
Brugia malayi	RE15519p	0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0042	0.2534	0.2505
Echinococcus granulosus	rhodopsin orphan GPCR	0.0042	0.2534	0.2505
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0042	0.2534	0.2505
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0042	0.2534	0.2505
Echinococcus multilocularis	allatostatin A receptor	0.0042	0.2534	0.2505
Echinococcus granulosus	neuropeptide Y receptor	0.0042	0.2534	0.2505
Onchocerca volvulus		0.0042	0.2534	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0042	0.2534	0.2505
Echinococcus multilocularis	neuropeptide Y receptor	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Echinococcus granulosus	g protein coupled receptor	0.0042	0.2534	0.2505
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.2534	0.2505
Loa Loa (eye worm)	G-protein coupled receptor	0.0042	0.2534	1
Brugia malayi	hypothetical protein	0.0042	0.2534	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0042	0.2534	0.2505
Echinococcus granulosus	7tm_1 domain containing protein	0.0042	0.2534	0.2505
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0042	0.2534	0.2505
Mycobacterium tuberculosis	Possible arabinofuranosyltransferase AftD	0.0018	0.0039	1
Brugia malayi	hypothetical protein	0.0042	0.2534	1
Schistosoma mansoni	hypothetical protein	0.0042	0.2534	0.2505
Trichomonas vaginalis	alpha-L-fucosidase, putative	0.0018	0.0039	0.5
Brugia malayi	hypothetical protein	0.0042	0.2534	1
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0042	0.2534	1
Loa Loa (eye worm)	neuropeptide F receptor	0.0042	0.2534	1
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0042	0.2534	0.2505
Echinococcus multilocularis	orexin receptor type 2	0.0042	0.2534	0.2505
Brugia malayi	G-protein coupled receptor	0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0042	0.2534	0.2505
Echinococcus granulosus	sex peptide receptor	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Echinococcus granulosus	7TM GPCR rhodopsin	0.0042	0.2534	0.2505
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0042	0.2534	0.2505
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0042	0.2534	0.2505
Echinococcus granulosus	neuropeptide s receptor	0.0042	0.2534	0.2505
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0039	0.5
Echinococcus granulosus	fmrfamide receptor	0.0042	0.2534	0.2505
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0042	0.2534	0.2505
Schistosoma mansoni	biogenic amine receptor	0.0042	0.2534	0.2505
Plasmodium falciparum	LCCL domain-containing protein	0.0018	0.0039	0.5
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0042	0.2534	1
Echinococcus granulosus	neuropeptides capa receptor	0.0042	0.2534	0.2505
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Brugia malayi	neuropeptide F receptor	0.0042	0.2534	1
Onchocerca volvulus		0.0042	0.2534	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0042	0.2534	0.2505
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0042	0.2534	0.2505
Brugia malayi	hypothetical protein	0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Onchocerca volvulus		0.0042	0.2534	1
Schistosoma mansoni	amine GPCR	0.0042	0.2534	0.2505
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Schistosoma mansoni	neuropeptide F-like receptor	0.0042	0.2534	0.2505
Echinococcus granulosus	neuropeptide receptor A26	0.0042	0.2534	0.2505
Echinococcus granulosus	neuropeptide receptor	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Brugia malayi	Melatonin receptor type 1A	0.0042	0.2534	1
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0039	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0039	0.5
Onchocerca volvulus		0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Brugia malayi	hypothetical protein	0.0042	0.2534	1
Echinococcus granulosus	neuropeptide receptor	0.0042	0.2534	0.2505
Brugia malayi	putative neuropeptide receptor	0.0042	0.2534	1
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0042	0.2534	0.2505
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0042	0.2534	0.2505
Echinococcus multilocularis	serotonin receptor	0.0042	0.2534	0.2505
Mycobacterium ulcerans	oxidase	0.0017	0	0.5
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Echinococcus granulosus	biogenic amine 5HT receptor	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0039	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.2534	0.2505
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0042	0.2534	0.2505
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0039	0.5
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Brugia malayi	Dopamine receptor	0.0042	0.2534	1
Echinococcus multilocularis	sex peptide receptor	0.0042	0.2534	0.2505
Brugia malayi	G protein-coupled receptor	0.0042	0.2534	1
Brugia malayi	Serotonin receptor	0.0042	0.2534	1
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0039	0.5
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0042	0.2534	0.2505
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0042	0.2534	0.2505
Brugia malayi	hypothetical protein	0.0042	0.2534	1
Echinococcus multilocularis	somatostatin receptor	0.0042	0.2534	0.2505
Echinococcus granulosus	serotonin receptor	0.0042	0.2534	0.2505
Echinococcus granulosus	neuropeptides capa receptor	0.0042	0.2534	0.2505
Brugia malayi	putative neuropeptide receptor NPR1	0.0042	0.2534	1
Onchocerca volvulus		0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Schistosoma mansoni	amine GPCR	0.0042	0.2534	0.2505
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0042	0.2534	0.2505
Echinococcus multilocularis	Coagulation factor 5 8 type, C terminal	0.0112	1	1
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0039	0.5
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0042	0.2534	0.2505
Plasmodium vivax	LCCL domain-containing protein	0.0018	0.0039	0.5
Brugia malayi	follicle stimulating hormone receptor	0.0042	0.2534	1
Echinococcus granulosus	hypothetical protein	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.2534	0.2505
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0039	0.5
Echinococcus multilocularis	dedicator of cytokinesis protein	0.0095	0.8127	0.812
Schistosoma mansoni	neuropeptide receptor	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Echinococcus multilocularis	neuropeptide s receptor	0.0042	0.2534	0.2505
Echinococcus granulosus	g-protein coupled receptor	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Plasmodium vivax	LCCL domain-containing protein	0.0018	0.0039	0.5
Schistosoma mansoni	myosin xvIII	0.0042	0.2534	0.2505
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.2534	0.2505
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0042	0.2534	0.2505
Echinococcus granulosus	tm gpcr rhodopsin	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Toxoplasma gondii	F5/8 type C domain-containing protein	0.0018	0.0039	0.5
Schistosoma mansoni	amine GPCR	0.0042	0.2534	0.2505
Brugia malayi	larval opioid receptor	0.0042	0.2534	1
Trichomonas vaginalis	hypothetical protein	0.0018	0.0039	0.5
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0042	0.2534	0.2505
Brugia malayi	GnHR receptor homolog	0.0042	0.2534	1
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0039	0.5
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0042	0.2534	0.2505
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0042	0.2534	0.2505
Brugia malayi	hypothetical protein	0.0042	0.2534	1
Schistosoma mansoni	neuropeptide receptor	0.0042	0.2534	0.2505
Echinococcus multilocularis	neuropeptide Y receptor	0.0042	0.2534	0.2505
Schistosoma mansoni	neuropeptide receptor	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0042	0.2534	0.2505
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0042	0.2534	0.2505
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0042	0.2534	0.2505
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0042	0.2534	0.2505
Schistosoma mansoni	opsin-like receptor	0.0042	0.2534	0.2505
Echinococcus multilocularis	g protein coupled receptor	0.0042	0.2534	0.2505
Toxoplasma gondii	PA14 domain-containing protein	0.0018	0.0039	0.5
Schistosoma mansoni	opsin-like receptor	0.0042	0.2534	0.2505
Trichomonas vaginalis	beta-hexosaminidase B, putative	0.0018	0.0039	0.5
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0042	0.2534	1
Toxoplasma gondii	F5/8 type C domain-containing protein	0.0018	0.0039	0.5
Echinococcus granulosus	g protein coupled receptor	0.0042	0.2534	0.2505
Brugia malayi	Dopamine receptor protein 1	0.0042	0.2534	1
Plasmodium falciparum	LCCL domain-containing protein	0.0018	0.0039	0.5
Brugia malayi	neuropeptide F receptor	0.0042	0.2534	1
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0042	0.2534	0.2505
Echinococcus granulosus	neuropeptide FF receptor 2	0.0042	0.2534	0.2505
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0042	0.2534	0.2505
Echinococcus multilocularis	g-protein coupled receptor	0.0042	0.2534	0.2505
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0042	0.2534	1
Onchocerca volvulus		0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0042	0.2534	1
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0039	0.5
Schistosoma mansoni	neuropeptide F-like receptor	0.0042	0.2534	0.2505
Echinococcus multilocularis	g protein coupled receptor	0.0042	0.2534	0.2505
Schistosoma mansoni	amine GPCR	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Toxoplasma gondii	F5/8 type C domain-containing protein	0.0018	0.0039	0.5
Loa Loa (eye worm)	melatonin receptor type 1A	0.0042	0.2534	1
Schistosoma mansoni	neuropeptide receptor	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Echinococcus multilocularis	G protein coupled receptor 139	0.0042	0.2534	0.2505
Echinococcus multilocularis	g protein coupled receptor	0.0042	0.2534	0.2505
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0042	0.2534	1
Echinococcus multilocularis	neuropeptides capa receptor	0.0042	0.2534	0.2505
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0039	0.5
Schistosoma mansoni	opsin-like receptor	0.0042	0.2534	0.2505
Schistosoma mansoni	dock	0.0112	1	1
Echinococcus granulosus	tm gpcr rhodopsin	0.0042	0.2534	0.2505
Echinococcus granulosus	rhodopsin orphan GPCR	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0042	0.2534	0.2505
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0042	0.2534	0.2505
Brugia malayi	Dopamine receptor protein 2	0.0042	0.2534	1
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0039	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.2534	0.2505
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0042	0.2534	0.2505
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0042	0.2534	0.2505
Schistosoma mansoni	histamine h1 receptor	0.0042	0.2534	0.2505
Schistosoma mansoni	neuropeptide f receptor 76f	0.0042	0.2534	0.2505
Schistosoma mansoni	growth hormone secretagogue receptor	0.0042	0.2534	0.2505
Brugia malayi	AKH receptor	0.0042	0.2534	1
Loa Loa (eye worm)	G-protein coupled receptor	0.0042	0.2534	1
Schistosoma mansoni	hypothetical protein	0.0042	0.2534	0.2505
Loa Loa (eye worm)	TYRA-2 protein	0.0042	0.2534	1
Brugia malayi	hypothetical protein	0.0042	0.2534	1
Mycobacterium leprae	PROBABLE CONSERVED TRANSMEMBRANE PROTEIN	0.0018	0.0039	0.5
Brugia malayi	G-protein coupled receptor	0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Onchocerca volvulus		0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0042	0.2534	0.2505
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0042	0.2534	1
Echinococcus granulosus	somatostatin receptor	0.0042	0.2534	0.2505
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Loa Loa (eye worm)	neuropeptide F receptor	0.0042	0.2534	1
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0039	0.5
Brugia malayi	hypothetical protein	0.0042	0.2534	1
Onchocerca volvulus		0.0042	0.2534	1
Brugia malayi	G protein-coupled receptor F59B2.13	0.0042	0.2534	1
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0042	0.2534	0.2505
Brugia malayi	ORL1-like opioid receptor	0.0042	0.2534	1
Echinococcus multilocularis	neuropeptide receptor	0.0042	0.2534	0.2505
Brugia malayi	hypothetical protein	0.0042	0.2534	1
Echinococcus granulosus	neuropeptide Y receptor	0.0042	0.2534	0.2505
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0042	0.2534	1
Echinococcus granulosus	orexin receptor type 2	0.0042	0.2534	0.2505
Echinococcus granulosus	G protein coupled receptor 139	0.0042	0.2534	0.2505
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0042	0.2534	0.2505
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0042	0.2534	1
Onchocerca volvulus		0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Onchocerca volvulus		0.0042	0.2534	1
Loa Loa (eye worm)	hypothetical protein	0.0042	0.2534	1
Echinococcus multilocularis	dro:myosuppressin receptor	0.0042	0.2534	0.2505
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0042	0.2534	0.2505
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0042	0.2534	0.2505
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0042	0.2534	0.2505
Echinococcus granulosus	dro:myosuppressin receptor	0.0042	0.2534	0.2505
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0042	0.2534	0.2505
Schistosoma mansoni	adenoreceptor	0.0042	0.2534	0.2505
Trichomonas vaginalis	conserved hypothetical protein	0.0018	0.0039	0.5
Echinococcus granulosus	allatostatin A receptor	0.0042	0.2534	0.2505
Schistosoma mansoni	amine GPCR	0.0042	0.2534	0.2505
Schistosoma mansoni	biogenic amine receptor	0.0042	0.2534	0.2505
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0042	0.2534	0.2505
Schistosoma mansoni	hypothetical protein	0.0042	0.2534	0.2505
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0042	0.2534	0.2505
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0042	0.2534	0.2505
Onchocerca volvulus		0.0042	0.2534	1
Onchocerca volvulus		0.0042	0.2534	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

Search by CAS
PubChem: 5487641

Bibliographic References

No literature references available for this target.

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Detailed information for compound 585474