Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0092 | 0.236 | 1 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0042 | 0.0667 | 0.1037 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0516 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0092 | 0.236 | 0.367 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0667 | 0.0667 |
Brugia malayi | RNA, U transporter 1 | 0.0085 | 0.2121 | 0.3298 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0042 | 0.0667 | 0.0667 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0516 | 0.0516 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0516 | 0.0802 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0516 | 0.0802 |
Trichomonas vaginalis | ABC transporter, half transporter, putative | 0.0042 | 0.0667 | 0.1037 |
Schistosoma mansoni | multidrug resistance protein | 0.0042 | 0.0667 | 0.0667 |
Trichomonas vaginalis | abcb9, putative | 0.0042 | 0.0667 | 0.1037 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0042 | 0.0667 | 0.0667 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0042 | 0.0667 | 0.1037 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0042 | 0.0667 | 0.1037 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0042 | 0.0667 | 0.0667 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0194 | 0.2911 |
Trichomonas vaginalis | ABC transporter, putative | 0.0042 | 0.0667 | 0.1037 |
Entamoeba histolytica | P-glycoprotein-2 | 0.0042 | 0.0667 | 0.1037 |
Trichomonas vaginalis | abcb9, putative | 0.0042 | 0.0667 | 0.1037 |
Echinococcus multilocularis | multidrug resistance protein 1 | 0.0042 | 0.0667 | 0.0667 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0042 | 0.0667 | 0.1037 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0212 | 0.643 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0516 | 0.0802 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.0194 | 0.2911 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0024 | 0.0075 | 0.1461 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0194 | 0.3762 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0042 | 0.0667 | 0.0667 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0999 | 0.1553 |
Leishmania major | ATP-binding cassette protein subfamily B, member 2, putative | 0.0042 | 0.0667 | 1 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0212 | 0.643 | 0.643 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0042 | 0.0667 | 0.1037 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0042 | 0.0667 | 0.1037 |
Trichomonas vaginalis | ABC transporter, putative | 0.0042 | 0.0667 | 0.1037 |
Entamoeba histolytica | glycogenphosphorylase, putative | 0.0092 | 0.236 | 0.367 |
Echinococcus granulosus | 5'partial|ATP binding cassette sub family B | 0.0041 | 0.0651 | 0.0651 |
Trichomonas vaginalis | ABC transporter, putative | 0.0042 | 0.0667 | 0.1037 |
Entamoeba histolytica | P-glyco protein 6, putative | 0.0042 | 0.0667 | 0.1037 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0516 | 0.0516 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0516 | 0.7737 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0516 | 1 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0212 | 0.643 | 0.643 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0516 | 0.0516 |
Brugia malayi | multidrug resistance protein 3 | 0.0042 | 0.0667 | 0.1037 |
Onchocerca volvulus | 0.0042 | 0.0667 | 0.0255 | |
Echinococcus multilocularis | snurportin 1 | 0.0318 | 1 | 1 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.003 | 0.0266 | 0.515 |
Schistosoma mansoni | hypothetical protein | 0.0318 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.5172 | 0.5172 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0318 | 1 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0516 | 0.0802 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0212 | 0.643 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0449 | 0.0698 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0516 | 0.0516 |
Loa Loa (eye worm) | multidrug resistance protein 3 | 0.0042 | 0.0667 | 0.0667 |
Entamoeba histolytica | P-glycoprotein-1 | 0.0042 | 0.0667 | 0.1037 |
Schistosoma mansoni | glycogen phosphorylase | 0.0092 | 0.236 | 0.236 |
Brugia malayi | Importin beta-1 subunit | 0.003 | 0.0266 | 0.0413 |
Entamoeba histolytica | P-glycoprotein-2 | 0.0042 | 0.0667 | 0.1037 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0516 | 1 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.003 | 0.0266 | 0.515 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.0194 | 0.3762 |
Echinococcus granulosus | glycogen phosphorylase | 0.0212 | 0.643 | 0.643 |
Schistosoma mansoni | multidrug resistance protein | 0.0042 | 0.0667 | 0.0667 |
Entamoeba histolytica | P-glycoprotein-5 | 0.0042 | 0.0667 | 0.1037 |
Plasmodium vivax | multidrug resistance protein 1, putative | 0.0042 | 0.0667 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0.0516 | 0.5 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0042 | 0.0667 | 0.1037 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0029 | 0.0242 | 0.0242 |
Leishmania major | p-glycoprotein | 0.0042 | 0.0667 | 1 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.003 | 0.0266 | 0.3985 |
Schistosoma mansoni | importin beta-1 | 0.003 | 0.0266 | 0.0266 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0212 | 0.643 | 0.643 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0516 | 0.0516 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0516 | 0.0516 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0042 | 0.0667 | 0.1037 |
Loa Loa (eye worm) | ATP-binding cassette sub-family B member 2 | 0.0042 | 0.0667 | 0.0667 |
Mycobacterium tuberculosis | Probable transmembrane multidrug efflux pump | 0.0042 | 0.0667 | 0.0223 |
Leishmania major | importin beta-1 subunit, putative | 0.0024 | 0.0075 | 0.113 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.0194 | 0.2911 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0092 | 0.236 | 0.2724 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0194 | 0.0302 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0042 | 0.0667 | 0.1037 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0042 | 0.0667 | 0.1037 |
Echinococcus multilocularis | multidrug resistance protein 1 | 0.0029 | 0.0242 | 0.0242 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0075 | 0.0117 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0516 | 0.0516 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0194 | 0.0194 |
Giardia lamblia | Glycogen phosphorylase | 0.0212 | 0.643 | 1 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0042 | 0.0667 | 0.0667 |
Trichomonas vaginalis | importin beta-1, putative | 0.0024 | 0.0075 | 0.0117 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0042 | 0.0667 | 0.0667 |
Schistosoma mansoni | glycogen phosphorylase | 0.0212 | 0.643 | 0.643 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0516 | 0.0516 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0042 | 0.0667 | 0.1037 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0516 | 0.0802 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0212 | 0.643 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0516 | 0.0802 |
Echinococcus multilocularis | ATP binding cassette sub family B | 0.0041 | 0.0651 | 0.0651 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0042 | 0.0667 | 0.0667 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0516 | 0.0802 |
Toxoplasma gondii | ATP-binding cassette transporter ABC.B1 | 0.0042 | 0.0667 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0516 | 0.0516 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0516 | 0.7737 |
Echinococcus granulosus | geminin | 0.0175 | 0.5172 | 0.5172 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0516 | 0.0516 |
Echinococcus multilocularis | multidrug resistance protein 1 | 0.0042 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0212 | 0.643 | 0.643 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.0194 | 0.2911 |
Trichomonas vaginalis | abcb9, putative | 0.0042 | 0.0667 | 0.1037 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0516 | 0.0516 |
Trichomonas vaginalis | taga, putative | 0.0042 | 0.0667 | 0.1037 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0.0516 | 0.5 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0042 | 0.0667 | 0.1037 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0029 | 0.0242 | 0.0376 |
Echinococcus multilocularis | geminin | 0.0175 | 0.5172 | 0.5172 |
Schistosoma mansoni | glycogen phosphorylase | 0.0212 | 0.643 | 0.643 |
Echinococcus multilocularis | importin subunit beta 1 | 0.003 | 0.0266 | 0.0266 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0999 | 0.1553 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0999 | 0.0999 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0266 | 0.0266 |
Brugia malayi | carbohydrate phosphorylase | 0.0212 | 0.643 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0449 | 0.0449 |
Trichomonas vaginalis | ABC transporter, putative | 0.0042 | 0.0667 | 0.1037 |
Schistosoma mansoni | multidrug resistance protein | 0.0042 | 0.0667 | 0.0667 |
Trichomonas vaginalis | ABC transporter, half transporter, putative | 0.0042 | 0.0667 | 0.1037 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.0075 | 0.0117 |
Plasmodium falciparum | multidrug resistance protein 1 | 0.0042 | 0.0667 | 1 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0042 | 0.0667 | 0.0667 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0042 | 0.0667 | 0.1037 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0667 | 0.0667 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0516 | 0.0802 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.5172 | 0.5172 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0999 | 0.0999 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0042 | 0.0667 | 0.1037 |
Echinococcus granulosus | importin subunit beta 1 | 0.003 | 0.0266 | 0.0266 |
Plasmodium falciparum | importin beta, putative | 0.003 | 0.0266 | 0.3985 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0516 | 0.0802 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0042 | 0.0667 | 0.1037 |
Echinococcus granulosus | glycogen phosphorylase | 0.0212 | 0.643 | 0.643 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0042 | 0.0667 | 0.0667 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0516 | 0.7737 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0212 | 0.643 | 0.643 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0237 | 0.7286 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.0194 | 0.3762 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0042 | 0.0667 | 0.1037 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0029 | 0.0242 | 0.0242 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0075 | 0.0117 |
Echinococcus granulosus | multidrug resistance protein 1 | 0.0042 | 0.0667 | 0.0667 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0212 | 0.643 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0651 | 0.0651 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0042 | 0.0667 | 0.1037 |
Trichomonas vaginalis | lipid A export ATP-binding/permease protein msba, putative | 0.0042 | 0.0667 | 0.1037 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0516 | 0.0516 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0449 | 0.0449 |
Entamoeba histolytica | P-glycoprotein-2, putative | 0.0042 | 0.0667 | 0.1037 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0516 | 0.0802 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0212 | 0.643 | 1 |
Schistosoma mansoni | smdr2 | 0.0042 | 0.0667 | 0.0667 |
Entamoeba histolytica | P-glycoprotein 5, putative | 0.0042 | 0.0667 | 0.1037 |
Toxoplasma gondii | ABC transporter transmembrane region domain-containing protein | 0.0042 | 0.0667 | 1 |
Trichomonas vaginalis | ATP-binding cassette transporter, putative | 0.0042 | 0.0667 | 0.1037 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.0194 | 0.2911 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0092 | 0.236 | 0.367 |
Plasmodium vivax | importin-beta 2, putative | 0.003 | 0.0266 | 0.3985 |
Echinococcus multilocularis | ATP binding cassette subfamily B (MDR:TAP) | 0.0042 | 0.0667 | 0.0667 |
Trichomonas vaginalis | multidrug resistance protein 1, 2, putative | 0.0042 | 0.0667 | 0.1037 |
Echinococcus granulosus | ATP binding cassette subfamily B MDR:TAP | 0.0042 | 0.0667 | 0.0667 |
Brugia malayi | ABC transporter family protein | 0.0042 | 0.0667 | 0.1037 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0212 | 0.643 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.