Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0046 | 0.0628 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.0628 | 0.0628 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0628 | 0.0628 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0046 | 0.0628 | 0.0628 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0046 | 0.0628 | 0.0628 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0628 | 0.0628 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0046 | 0.0628 | 0.0628 |
Echinococcus granulosus | carboxylesterase 5A | 0.0269 | 1 | 1 |
Echinococcus multilocularis | neuroligin | 0.0046 | 0.0628 | 0.0628 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0046 | 0.0628 | 0.0628 |
Onchocerca volvulus | 0.0046 | 0.0628 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0628 | 0.0628 |
Schistosoma mansoni | gliotactin | 0.0046 | 0.0628 | 0.0628 |
Loa Loa (eye worm) | carboxylesterase | 0.0269 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0269 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0269 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.0628 | 0.0628 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0628 | 0.0628 |
Onchocerca volvulus | 0.0046 | 0.0628 | 1 | |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0046 | 0.0628 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0046 | 0.0628 | 0.0628 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0269 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0269 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0628 | 0.0628 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.0628 | 0.0628 |
Onchocerca volvulus | 0.0046 | 0.0628 | 1 | |
Loa Loa (eye worm) | carboxylesterase | 0.0046 | 0.0628 | 0.0628 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0628 | 0.0628 |
Onchocerca volvulus | 0.0046 | 0.0628 | 1 | |
Onchocerca volvulus | 0.0046 | 0.0628 | 1 | |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0046 | 0.0628 | 0.0628 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0046 | 0.0628 | 0.0628 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0046 | 0.0628 | 0.0628 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0046 | 0.0628 | 0.5 |
Schistosoma mansoni | acetylcholinesterase | 0.0046 | 0.0628 | 0.0628 |
Echinococcus granulosus | acetylcholinesterase | 0.0269 | 1 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0046 | 0.0628 | 0.0628 |
Loa Loa (eye worm) | carboxylesterase | 0.0046 | 0.0628 | 0.0628 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0046 | 0.0628 | 0.5 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0046 | 0.0628 | 0.5 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0046 | 0.0628 | 0.0628 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0046 | 0.0628 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0628 | 0.0628 |
Echinococcus multilocularis | acetylcholinesterase | 0.0269 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0269 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0269 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0269 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0628 | 0.0628 |
Brugia malayi | Carboxylesterase family protein | 0.0046 | 0.0628 | 0.0628 |
Echinococcus granulosus | neuroligin | 0.0046 | 0.0628 | 0.0628 |
Loa Loa (eye worm) | hypothetical protein | 0.0269 | 1 | 1 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0046 | 0.0628 | 0.0628 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.