Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | solute carrier family 12 member 1 | 0.0056 | 0.3062 | 0.3062 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0101 | 0.0101 |
Brugia malayi | solute carrier family 12 member 1 | 0.0075 | 0.5192 | 0.5192 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1013 | 0.1013 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.012 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.2231 | 0.2231 |
Brugia malayi | Hypothetical 112.3 kDa protein K02A2.3 in chromosome II | 0.0057 | 0.3143 | 0.3143 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0075 | 0.5192 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0075 | 0.5192 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0075 | 0.5192 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.2231 | 0.2231 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.2231 | 0.2231 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.012 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0101 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1013 | 0.1013 |
Loa Loa (eye worm) | amino acid permease | 0.0037 | 0.1013 | 0.1013 |
Schistosoma mansoni | solute carrier family 12 electroneutral k-cl cotransporter | 0.0057 | 0.3143 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0101 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.3143 | 0.3143 |
Brugia malayi | Amino acid permease family protein | 0.0057 | 0.3143 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.3143 | 0.3143 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0067 | 0.4279 | 0.8243 |
Onchocerca volvulus | 0.0048 | 0.215 | 0.5 | |
Echinococcus granulosus | solute carrier family 12 | 0.0057 | 0.3143 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.3143 | 0.3143 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1013 | 0.1013 |
Echinococcus multilocularis | solute carrier family 12 | 0.0057 | 0.3143 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1013 | 0.1013 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0101 | 0.0101 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.