Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0038 | 0.0461 | 0.0461 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.1691 | 0.1368 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0038 | 0.0461 | 0.0461 |
Echinococcus granulosus | muscleblind protein | 0.0162 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 1 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0038 | 0.0461 | 0.0461 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0461 | 0.0461 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0461 | 0.0461 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0038 | 0.0461 | 0.0461 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0461 | 0.0461 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0162 | 1 | 1 |
Onchocerca volvulus | 0.0082 | 0.3858 | 1 | |
Echinococcus multilocularis | muscleblind protein | 0.0162 | 1 | 1 |
Brugia malayi | Thrombospondin type 1 domain containing protein | 0.0082 | 0.3858 | 0.362 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 1 | 1 |
Brugia malayi | Type I phosphodiesterase / nucleotide pyrophosphatase family protein | 0.0038 | 0.0461 | 0.009 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0038 | 0.0461 | 0.025 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1691 | 0.1691 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.3858 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0038 | 0.0461 | 0.0461 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0038 | 0.0461 | 0.0461 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0038 | 0.0461 | 0.0461 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0038 | 0.0461 | 0.0461 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0038 | 0.0461 | 0.025 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0038 | 0.0461 | 0.025 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.0082 | 0.3858 | 0.3858 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0374 | 0.0374 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.1691 | 0.1368 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0038 | 0.0461 | 0.025 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0038 | 0.0461 | 0.0461 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0038 | 0.0461 | 0.0461 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0038 | 0.0461 | 0.0461 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.1691 | 0.1691 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.