Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.4147 | 0.3936 |
Trypanosoma cruzi | endonuclease G, putative | 0.0101 | 0.2131 | 1 |
Echinococcus multilocularis | ectonucleotide | 0.0142 | 0.3353 | 0.3613 |
Onchocerca volvulus | 0.0364 | 1 | 1 | |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0169 | 0.4147 | 0.4147 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0169 | 0.4147 | 0.4469 |
Brugia malayi | Type I phosphodiesterase / nucleotide pyrophosphatase family protein | 0.0169 | 0.4147 | 0.4147 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0142 | 0.3353 | 0.3613 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.034 | 0.9281 | 1 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0169 | 0.4147 | 0.4147 |
Schistosoma mansoni | endonuclease related | 0.0101 | 0.2131 | 0.2131 |
Mycobacterium tuberculosis | Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) | 0.0125 | 0.2856 | 0.5 |
Mycobacterium ulcerans | phosphotyrosine protein phosphatase PtpA | 0.0181 | 0.4532 | 0.5 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0181 | 0.4532 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.4147 | 0.3936 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0181 | 0.4532 | 1 |
Trypanosoma cruzi | endonuclease G, putative | 0.0101 | 0.2131 | 1 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.034 | 0.9281 | 1 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.034 | 0.9281 | 0.9281 |
Echinococcus granulosus | Endonuclease G | 0.0101 | 0.2131 | 0.2296 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.0364 | 1 | 1 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0169 | 0.4147 | 0.4147 |
Leishmania major | endonuclease G, putative | 0.0101 | 0.2131 | 1 |
Echinococcus granulosus | ectonucleotide | 0.0142 | 0.3353 | 0.3613 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0169 | 0.4147 | 0.4469 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.034 | 0.9281 | 0.9281 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0181 | 0.4532 | 1 |
Toxoplasma gondii | DNA/RNA non-specific endonuclease | 0.0101 | 0.2131 | 0.5 |
Trypanosoma brucei | endonuclease G, putative | 0.0101 | 0.2131 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0169 | 0.4147 | 0.4469 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0181 | 0.4532 | 1 |
Giardia lamblia | Low molecular weight protein-tyrosine-phosphatase | 0.0181 | 0.4532 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0169 | 0.4147 | 0.4469 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0181 | 0.4532 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0142 | 0.3353 | 0.3353 |
Schistosoma mansoni | hypothetical protein | 0.0364 | 1 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0169 | 0.4147 | 0.4469 |
Trypanosoma brucei | endonuclease G, putative | 0.0101 | 0.2131 | 1 |
Echinococcus multilocularis | geminin | 0.0142 | 0.3353 | 0.3613 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0181 | 0.4532 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0169 | 0.4147 | 0.4469 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0169 | 0.4147 | 0.4469 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0169 | 0.4147 | 0.4469 |
Leishmania major | DNA/RNA non-specific endonuclease-like protein | 0.0101 | 0.2131 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0042 | 0.0349 | 0.0349 |
Schistosoma mansoni | hypothetical protein | 0.0142 | 0.3353 | 0.3353 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0181 | 0.4532 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0169 | 0.4147 | 0.4469 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0181 | 0.4532 | 1 |
Echinococcus granulosus | geminin | 0.0142 | 0.3353 | 0.3613 |
Onchocerca volvulus | 0.0181 | 0.4532 | 0.0657 | |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0042 | 0.0349 | 0.0349 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0101 | 0.2131 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0142 | 0.3353 | 0.3613 |
Brugia malayi | endonuclease G, mitochondrial precursor | 0.0101 | 0.2131 | 0.2131 |
Echinococcus multilocularis | Endonuclease G | 0.0101 | 0.2131 | 0.2296 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.034 | 0.9281 | 0.9255 |
Loa Loa (eye worm) | phosphotyrosine protein phosphatase | 0.0181 | 0.4532 | 0.4335 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0169 | 0.4147 | 0.4147 |
Trypanosoma brucei | endonuclease G, putative | 0.0101 | 0.2131 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0169 | 0.4147 | 0.4469 |
Brugia malayi | Low molecular weight phosphotyrosine protein phosphatase containing protein | 0.0181 | 0.4532 | 0.4532 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0169 | 0.4147 | 0.4469 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.3353 | 0.3113 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0101 | 0.2131 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.4147 | 0.3936 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.