Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0556 | 0.4933 | 1 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase zeta | 0.0065 | 0.0077 | 0.0077 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.0147 | 0.0888 | 0.0888 |
Onchocerca volvulus | 0.0556 | 0.4933 | 1 | |
Onchocerca volvulus | 0.0158 | 0.0993 | 0.1838 | |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.0899 | 0.0899 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0556 | 0.4933 | 1 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0065 | 0.0077 | 0.0077 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0068 | 0.0106 | 0.0106 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0556 | 0.4933 | 0.5 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0068 | 0.0106 | 0.0029 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0068 | 0.0106 | 0.0106 |
Loa Loa (eye worm) | fibronectin type III domain-containing protein | 0.0065 | 0.0077 | 0.0077 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0065 | 0.0077 | 0.0077 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.1451 | 0.1451 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0068 | 0.0106 | 0.0106 |
Schistosoma mansoni | hypothetical protein | 0.0147 | 0.0888 | 0.0817 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0106 | 0.0106 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0068 | 0.0106 | 0.0106 |
Mycobacterium ulcerans | phosphotyrosine protein phosphatase PtpA | 0.0556 | 0.4933 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.0899 | 0.0899 |
Mycobacterium tuberculosis | Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) | 0.0385 | 0.3237 | 0.5 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0065 | 0.0077 | 0.0077 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0068 | 0.0106 | 0.0106 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0556 | 0.4933 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0068 | 0.0106 | 0.0106 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0556 | 0.4933 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0106 | 0.0106 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0171 | 0.1128 | 0.5 |
Brugia malayi | Protein-tyrosine phosphatase | 0.0214 | 0.1545 | 0.1454 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0068 | 0.0106 | 0.0106 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0068 | 0.0106 | 0.0029 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0065 | 0.0077 | 0.0077 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0065 | 0.0077 | 0.0077 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.1068 | 1 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0068 | 0.0106 | 0.0106 |
Onchocerca volvulus | 0.0147 | 0.0888 | 0.1619 | |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0068 | 0.0106 | 0.0106 |
Trypanosoma brucei | low molecular weight protein tyrosine phosphatase, putative | 0.0171 | 0.1128 | 0.5 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0065 | 0.0077 | 0.0077 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.1068 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0106 | 0.0106 |
Leishmania major | hypothetical protein, conserved | 0.0171 | 0.1128 | 0.5 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0068 | 0.0106 | 0.0029 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0068 | 0.0106 | 0.0106 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.0899 | 0.0899 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0171 | 0.1128 | 0.5 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.1068 | 1 | 1 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0065 | 0.0077 | 0.0077 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0556 | 0.4933 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0053 | 0.0053 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.1068 | 1 | 1 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0556 | 0.4933 | 1 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0556 | 0.4933 | 1 |
Loa Loa (eye worm) | phosphotyrosine protein phosphatase | 0.0556 | 0.4933 | 0.4933 |
Giardia lamblia | Low molecular weight protein-tyrosine-phosphatase | 0.0556 | 0.4933 | 0.5 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0068 | 0.0106 | 0.0029 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase zeta | 0.0065 | 0.0077 | 0.0077 |
Brugia malayi | Low molecular weight phosphotyrosine protein phosphatase containing protein | 0.0556 | 0.4933 | 0.4879 |
Brugia malayi | Thrombospondin type 1 domain containing protein | 0.0147 | 0.0888 | 0.079 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0068 | 0.0106 | 0.0106 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type | 0.0065 | 0.0077 | 0.0077 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.