Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.5326 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0079 | 0.0727 | 0.1208 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0191 | 0.3153 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0079 | 0.0727 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.1154 | 0.1918 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0727 | 0.1208 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.3153 | 0.5275 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0727 | 0.1208 |
Brugia malayi | beta-lactamase family protein | 0.0079 | 0.0727 | 0.1208 |
Loa Loa (eye worm) | beta-lactamase | 0.0079 | 0.0727 | 0.1208 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0101 | 0.1192 | 0.3084 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0727 | 0.1208 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0079 | 0.0727 | 0.1208 |
Mycobacterium tuberculosis | Probable transcriptional regulatory protein (LuxR-family) | 0.0395 | 0.7562 | 0.7371 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.3153 | 0.5275 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0079 | 0.0727 | 0.188 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.5326 | 1 |
Mycobacterium ulcerans | two component transcriptional regulatory protein DevR | 0.0395 | 0.7562 | 1 |
Echinococcus multilocularis | geminin | 0.0169 | 0.2672 | 0.6911 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.5326 | 1 |
Mycobacterium tuberculosis | Possible nitrate/nitrite response transcriptional regulatory protein NarL | 0.0395 | 0.7562 | 0.7371 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.3153 | 0.5275 |
Plasmodium vivax | hypothetical protein, conserved | 0.0079 | 0.0727 | 0.5 |
Echinococcus granulosus | geminin | 0.0169 | 0.2672 | 0.6911 |
Mycobacterium ulcerans | two component transcriptional regulator | 0.0395 | 0.7562 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.5326 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0202 | 0.3376 | 0.576 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.5326 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0079 | 0.0727 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.3153 | 0.5275 |
Loa Loa (eye worm) | hypothetical protein | 0.0323 | 0.6014 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.2672 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0079 | 0.0727 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0099 | 0.1154 | 0.1918 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0079 | 0.0727 | 0.188 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0079 | 0.0727 | 0.1208 |
Mycobacterium tuberculosis | Possible two component transcriptional regulatory protein (probably LuxR-family) | 0.0395 | 0.7562 | 0.7371 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0101 | 0.1192 | 0.3084 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0727 | 0.1208 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.1154 | 0.4318 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0079 | 0.0727 | 0.272 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0101 | 0.1192 | 0.1982 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0224 | 0.3866 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0727 | 0.1208 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0145 | 0.2148 | 0.3571 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.3153 | 0.5275 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.5326 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0395 | 0.7562 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0101 | 0.1192 | 0.1982 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.3153 | 0.5275 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0291 | 0.5326 | 0.8856 |
Mycobacterium tuberculosis | Probable transcriptional regulatory protein (probably LuxR/UhpA-family) | 0.0395 | 0.7562 | 0.7371 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0101 | 0.1192 | 0.4462 |
Brugia malayi | beta-lactamase | 0.0079 | 0.0727 | 0.1208 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0079 | 0.0727 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0323 | 0.6014 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0291 | 0.5326 | 0.8856 |
Mycobacterium ulcerans | putative regulatory protein | 0.0395 | 0.7562 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0145 | 0.2148 | 0.3571 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0202 | 0.3376 | 0.576 |
Mycobacterium ulcerans | nitrate/nitrite response regulator protein NarL | 0.0395 | 0.7562 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0101 | 0.1192 | 0.3084 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.2672 | 1 |
Mycobacterium leprae | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN | 0.0395 | 0.7562 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.3153 | 0.5275 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0079 | 0.0727 | 0.272 |
Mycobacterium tuberculosis | Probable transcriptional regulatory protein | 0.0395 | 0.7562 | 0.7371 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0224 | 0.3866 | 1 |
Mycobacterium tuberculosis | Possible transcriptional regulatory protein | 0.0395 | 0.7562 | 0.7371 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0101 | 0.1192 | 0.3084 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0101 | 0.1192 | 0.4462 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0079 | 0.0727 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0727 | 0.1208 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0101 | 0.1192 | 0.4462 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.