Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.0084 | 0.2654 | 1 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0084 | 0.2654 | 1 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.0084 | 0.2654 | 1 |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.0084 | 0.2654 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.175 | 0.175 |
Plasmodium vivax | methionine aminopeptidase 1a, putative | 0.0084 | 0.2654 | 1 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0084 | 0.2654 | 1 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.0084 | 0.2654 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.175 | 0.175 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.175 | 0.175 |
Toxoplasma gondii | methionine aminopeptidase | 0.0084 | 0.2654 | 1 |
Schistosoma mansoni | glutaminase | 0.0267 | 1 | 1 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0084 | 0.2654 | 1 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.0084 | 0.2654 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.175 | 0.175 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0084 | 0.2654 | 1 |
Toxoplasma gondii | methionine aminopeptidase, type i, putative | 0.0084 | 0.2654 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.175 | 0.6593 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.0084 | 0.2654 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.175 | 0.175 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.175 | 0.175 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0018 | 0 | 0.5 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0084 | 0.2654 | 0.5 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0084 | 0.2654 | 0.2654 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.175 | 0.6593 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.0084 | 0.2654 | 1 |
Plasmodium falciparum | methionine aminopeptidase 1a, putative | 0.0084 | 0.2654 | 1 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0084 | 0.2654 | 1 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.0084 | 0.2654 | 1 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0084 | 0.2654 | 1 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0018 | 0 | 0.5 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.0084 | 0.2654 | 1 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.0084 | 0.2654 | 0.2654 |
Loa Loa (eye worm) | glutaminase 2 | 0.0267 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.175 | 0.175 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.175 | 0.175 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.0084 | 0.2654 | 1 |
Loa Loa (eye worm) | glutaminase | 0.0267 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0062 | 0.175 | 0.175 |
Mycobacterium ulcerans | glutaminase | 0.0267 | 1 | 1 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.0084 | 0.2654 | 0.2654 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.175 | 0.175 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0084 | 0.2654 | 0.2654 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0084 | 0.2654 | 1 |
Trichomonas vaginalis | glutaminase, putative | 0.0267 | 1 | 1 |
Toxoplasma gondii | methionine aminopeptidase | 0.0084 | 0.2654 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.175 | 0.175 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.0084 | 0.2654 | 0.2654 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.0084 | 0.2654 | 0.2654 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.