Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | prolyl oligopeptidase family protein | 0.0195 | 0.3638 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.2928 | 0.4886 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0083 | 0.0229 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0065 | 0.0388 | 0.0523 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.2928 | 0.4886 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0065 | 0.0388 | 0.5 |
Loa Loa (eye worm) | STAT protein | 0.0158 | 0.2724 | 0.7488 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0065 | 0.0388 | 0.5 |
Echinococcus multilocularis | geminin | 0.0167 | 0.2928 | 0.2868 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0065 | 0.0388 | 0.5 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0185 | 0.3385 | 0.333 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0448 | 1 | 1 |
Brugia malayi | STAT protein, DNA binding domain containing protein | 0.0158 | 0.2724 | 0.7488 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0065 | 0.0388 | 0.5 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0195 | 0.3638 | 0.3584 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0065 | 0.0388 | 0.1067 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0448 | 1 | 1 |
Loa Loa (eye worm) | MBCTL1 | 0.0053 | 0.0083 | 0.0229 |
Schistosoma mansoni | hypothetical protein | 0.0285 | 0.5905 | 1 |
Echinococcus granulosus | geminin | 0.0167 | 0.2928 | 0.2868 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0195 | 0.3638 | 0.3584 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0448 | 1 | 1 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0195 | 0.3638 | 0.6106 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0053 | 0.0083 | 0.0229 |
Toxoplasma gondii | 1,3-beta-glucan synthase component protein | 0.0222 | 0.433 | 1 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0065 | 0.0388 | 0.5 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0065 | 0.0388 | 0.0307 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0185 | 0.3385 | 0.333 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.0195 | 0.3638 | 0.5 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0195 | 0.3638 | 1 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0065 | 0.0388 | 0.0307 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED40 (functional) | NA 0 uM kg-1 | In vivo inhibition of rat dermal passive revers arthus reaction following p.o. administration; Inactive. | ChEMBL. | 2970549 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.