Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0249 | 0.0000000054327 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0021 | 0.6548 | 0.5 |
Schistosoma mansoni | DNA helicase recq1 | 0.0021 | 0.6548 | 0.6548 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 1 | 1 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.6548 | 0.5438 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.2432 | 0.2239 |
Schistosoma mansoni | DNA helicase recq5 | 0.0021 | 0.6548 | 0.6548 |
Entamoeba histolytica | recQ family helicase, putative | 0.0021 | 0.6548 | 1 |
Echinococcus granulosus | lamin | 0.0026 | 1 | 1 |
Treponema pallidum | ATP-dependent DNA helicase | 0.0011 | 0.0249 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 1 | 1 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0021 | 0.6548 | 0.5 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.6548 | 1 |
Onchocerca volvulus | 0.0026 | 1 | 0.5 | |
Onchocerca volvulus | 0.0026 | 1 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.9702 | 0.9694 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.6548 | 0.5 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0021 | 0.6548 | 0.5438 |
Loa Loa (eye worm) | RecQ helicase | 0.0021 | 0.6548 | 0.646 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0021 | 0.6548 | 0.5907 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0021 | 0.6548 | 0.5 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 1 | 1 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.6548 | 0.5438 |
Schistosoma mansoni | lamin | 0.0026 | 1 | 1 |
Echinococcus multilocularis | musashi | 0.0026 | 1 | 1 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0021 | 0.6548 | 0.5907 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.1567 | 0.1351 |
Echinococcus multilocularis | bloom syndrome protein | 0.0021 | 0.6548 | 0.5907 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0021 | 0.6548 | 0.5 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0021 | 0.6548 | 0.646 |
Entamoeba histolytica | recQ family DNA helicase | 0.0011 | 0.0249 | 0.0381 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0021 | 0.6548 | 0.5 |
Echinococcus multilocularis | lamin | 0.0026 | 1 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0011 | 0.0249 | 0.0381 |
Echinococcus granulosus | bloom syndrome protein | 0.0021 | 0.6548 | 0.5907 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 1 | 1 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0011 | 0.0249 | 0.0249 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1269 | 0.1046 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0021 | 0.6548 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1269 | 0.1046 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.6548 | 0.646 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0021 | 0.6548 | 1 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0021 | 0.6548 | 0.5907 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 1 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 1 | 1 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0021 | 0.6548 | 0.5 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 1 | 1 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0021 | 0.6548 | 0.5907 |
Schistosoma mansoni | lamin | 0.0026 | 1 | 1 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0011 | 0.0249 | 1 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0021 | 0.6548 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.