Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0089 | 0.1103 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.1103 | 0.1103 |
Loa Loa (eye worm) | carboxylesterase | 0.0089 | 0.1103 | 0.1103 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0327 | 0.0327 |
Onchocerca volvulus | 0.0089 | 0.1103 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.2805 | 0.2805 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0327 | 0.0327 |
Echinococcus granulosus | acetylcholinesterase | 0.0529 | 1 | 1 |
Schistosoma mansoni | gliotactin | 0.0089 | 0.1103 | 0.1103 |
Schistosoma mansoni | acetylcholinesterase | 0.0089 | 0.1103 | 0.1103 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0002 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0529 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.1103 | 0.1103 |
Onchocerca volvulus | 0.0089 | 0.1103 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0529 | 1 | 1 |
Onchocerca volvulus | 0.0089 | 0.1103 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0089 | 0.1103 | 0.1103 |
Brugia malayi | Carboxylesterase family protein | 0.0089 | 0.1103 | 0.1103 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.2805 | 0.2805 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0089 | 0.1103 | 0.1103 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0089 | 0.1103 | 0.1103 |
Loa Loa (eye worm) | carboxylesterase | 0.0529 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0089 | 0.1103 | 0.1103 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0089 | 0.1103 | 0.1101 |
Echinococcus granulosus | geminin | 0.0174 | 0.2805 | 0.2804 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.1103 | 0.1103 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0089 | 0.1103 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0002 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.1103 | 0.1103 |
Echinococcus granulosus | neuroligin | 0.0089 | 0.1103 | 0.1101 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0089 | 0.1103 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.1103 | 0.1103 |
Brugia malayi | Carboxylesterase family protein | 0.0529 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0529 | 1 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0089 | 0.1103 | 0.1101 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0002 | 0.0002 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0089 | 0.1103 | 0.1101 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0089 | 0.1103 | 0.1103 |
Echinococcus multilocularis | geminin | 0.0174 | 0.2805 | 0.2804 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0089 | 0.1103 | 0.1101 |
Brugia malayi | Carboxylesterase family protein | 0.0089 | 0.1103 | 0.1103 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0089 | 0.1103 | 0.1101 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0089 | 0.1103 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0529 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0089 | 0.1103 | 0.5 |
Onchocerca volvulus | 0.0089 | 0.1103 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0529 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0327 | 0.0327 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0089 | 0.1103 | 0.1103 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.1103 | 0.1103 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0089 | 0.1103 | 0.1101 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0529 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0529 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0089 | 0.1103 | 0.1103 |
Loa Loa (eye worm) | carboxylesterase | 0.0089 | 0.1103 | 0.1103 |
Echinococcus granulosus | carboxylesterase 5A | 0.0529 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0089 | 0.1103 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0089 | 0.1103 | 0.1103 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0002 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0002 | 0.0002 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0002 | 0.5 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0089 | 0.1103 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0327 | 0.0327 |
Echinococcus multilocularis | neuroligin | 0.0089 | 0.1103 | 0.1101 |
Loa Loa (eye worm) | hypothetical protein | 0.0529 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.1103 | 0.1103 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.