Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | flap endonuclease 1 | 0.0025 | 0 | 0.5 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0063 | 0.1105 | 1 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0063 | 0.1105 | 1 |
Trypanosoma cruzi | Carboxypeptidase-like protein | 0.0063 | 0.1105 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.421 | 0.3491 |
Trypanosoma cruzi | metallo-peptidase, Clan MC, Family M14, putative | 0.0063 | 0.1105 | 1 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0063 | 0.1105 | 1 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0063 | 0.1105 | 1 |
Leishmania major | zinc carboxypeptidase, putative,metallo-peptidase, Clan MC, Family M14 | 0.0063 | 0.1105 | 1 |
Echinococcus multilocularis | Zinc carboxypeptidase family protein | 0.0063 | 0.1105 | 0.1105 |
Echinococcus multilocularis | subfamily M14A unassigned peptidase | 0.0366 | 1 | 1 |
Leishmania major | zinc carboxypeptidase, putative,metallo-peptidase, Clan MC, Family M14 | 0.0063 | 0.1105 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1105 | 0.1354 |
Trypanosoma brucei | Carboxypeptidase-like protein | 0.0063 | 0.1105 | 1 |
Brugia malayi | Zinc carboxypeptidase family protein | 0.0063 | 0.1105 | 1 |
Trypanosoma cruzi | metallo-peptidase, Clan MC, Family M14 | 0.0063 | 0.1105 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0303 | 0.8157 | 1 |
Trypanosoma brucei | metallo-peptidase, Clan MC, Family M14, putative | 0.0063 | 0.1105 | 1 |
Onchocerca volvulus | 0.0366 | 1 | 1 | |
Echinococcus granulosus | cytosolic carboxypeptidase 1 | 0.0063 | 0.1105 | 0.1105 |
Onchocerca volvulus | 0.0366 | 1 | 1 | |
Entamoeba histolytica | Flap nuclease, putative | 0.0025 | 0 | 0.5 |
Leishmania major | zinc carboxypeptidase, putative,metallo-peptidase, Clan MC, Family M14 | 0.0063 | 0.1105 | 1 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0063 | 0.1105 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0169 | 0.421 | 0.3491 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0063 | 0.1105 | 1 |
Loa Loa (eye worm) | zinc carboxypeptidase | 0.0063 | 0.1105 | 0.1354 |
Onchocerca volvulus | 0.0366 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1105 | 0.1354 |
Brugia malayi | Zinc carboxypeptidase family protein | 0.0063 | 0.1105 | 1 |
Loa Loa (eye worm) | zinc carboxypeptidase | 0.0063 | 0.1105 | 0.1354 |
Echinococcus granulosus | Zinc carboxypeptidase family protein | 0.0063 | 0.1105 | 0.1105 |
Brugia malayi | Zinc carboxypeptidase family protein | 0.0063 | 0.1105 | 1 |
Giardia lamblia | Nuclear ATP/GTP-binding protein | 0.0063 | 0.1105 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1105 | 0.1354 |
Onchocerca volvulus | Subfamily M14A unassigned peptidase homolog | 0.0366 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1105 | 0.1354 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1105 | 0.1354 |
Brugia malayi | Zinc carboxypeptidase family protein | 0.0063 | 0.1105 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1105 | 0.1354 |
Brugia malayi | Zinc carboxypeptidase family protein | 0.0063 | 0.1105 | 1 |
Brugia malayi | Zinc carboxypeptidase family protein | 0.0063 | 0.1105 | 1 |
Toxoplasma gondii | flagellar/basal body protein | 0.0063 | 0.1105 | 1 |
Loa Loa (eye worm) | zinc carboxypeptidase | 0.0063 | 0.1105 | 0.1354 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1105 | 0.1354 |
Echinococcus multilocularis | cytosolic carboxypeptidase protein 5 | 0.0063 | 0.1105 | 0.1105 |
Echinococcus multilocularis | geminin | 0.0169 | 0.421 | 0.421 |
Loa Loa (eye worm) | zinc carboxypeptidase | 0.0063 | 0.1105 | 0.1354 |
Giardia lamblia | Nuclear ATP/GTP-binding protein | 0.0063 | 0.1105 | 1 |
Schistosoma mansoni | subfamily M14A unassigned peptidase (M14 family) | 0.0366 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1105 | 0.1354 |
Toxoplasma gondii | zinc carboxypeptidase, putative | 0.0063 | 0.1105 | 1 |
Giardia lamblia | Nuclear ATP/GTP-binding protein | 0.0063 | 0.1105 | 1 |
Echinococcus granulosus | cytosolic carboxypeptidase protein 5 | 0.0063 | 0.1105 | 0.1105 |
Brugia malayi | Carboxypeptidase A2 precursor | 0.0063 | 0.1105 | 1 |
Brugia malayi | Zinc carboxypeptidase family protein | 0.0063 | 0.1105 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0063 | 0.1105 | 1 |
Echinococcus granulosus | geminin | 0.0169 | 0.421 | 0.421 |
Trypanosoma cruzi | zinc carboxypeptidase, putative | 0.0063 | 0.1105 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1105 | 0.1354 |
Toxoplasma gondii | zinc carboxypeptidase superfamily protein | 0.0063 | 0.1105 | 1 |
Trypanosoma cruzi | metallo-peptidase, Clan MC, Family M14, putative | 0.0063 | 0.1105 | 1 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0063 | 0.1105 | 1 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0063 | 0.1105 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.1105 | 0.1354 |
Onchocerca volvulus | 0.0366 | 1 | 1 | |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0063 | 0.1105 | 1 |
Trypanosoma brucei | metallo-peptidase, Clan MC, Family M14, putative | 0.0063 | 0.1105 | 1 |
Toxoplasma gondii | zinc carboxypeptidase superfamily protein | 0.0063 | 0.1105 | 1 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0063 | 0.1105 | 1 |
Brugia malayi | Zinc carboxypeptidase family protein | 0.0063 | 0.1105 | 1 |
Trichomonas vaginalis | Clan MC, family M14, Zinc carboxypeptidase-like metallopeptidase | 0.0063 | 0.1105 | 1 |
Echinococcus multilocularis | 0.0063 | 0.1105 | 0.1105 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.