Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | methionyl tRNA synthetase, cytoplasmic | 0.0201 | 0.8353 | 1 |
Echinococcus granulosus | methionyl tRNA synthetase cytoplasmic | 0.0201 | 0.8353 | 1 |
Entamoeba histolytica | methionyl-tRNA synthetase, putative | 0.0235 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0201 | 0.8353 | 0.9928 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.687 | 0.8225 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0103 | 0.3473 | 0.3473 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0103 | 0.3473 | 0.4127 |
Echinococcus granulosus | aminoacyl tRNA synthase complex interacting | 0.0033 | 0.0039 | 0.0047 |
Plasmodium falciparum | tRNA import protein tRIP | 0.0033 | 0.0039 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0103 | 0.3473 | 0.3473 |
Wolbachia endosymbiont of Brugia malayi | phenylalanyl-tRNA synthetase subunit beta | 0.0033 | 0.0039 | 0.5 |
Giardia lamblia | Methionyl-tRNA synthetase | 0.0033 | 0.0039 | 0.5 |
Chlamydia trachomatis | methionine--tRNA ligase | 0.0201 | 0.8353 | 1 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.1865 | 0.2233 |
Plasmodium vivax | methionine-tRNA ligase, putative | 0.0033 | 0.0039 | 0.5 |
Echinococcus multilocularis | aminoacyl tRNA synthase complex interacting | 0.0033 | 0.0039 | 0.0047 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0039 | 0.5 |
Echinococcus multilocularis | geminin | 0.0171 | 0.687 | 0.8225 |
Schistosoma mansoni | tyrosyl-tRNA synthetase | 0.0033 | 0.0039 | 0.0047 |
Treponema pallidum | methionyl-tRNA synthetase | 0.0235 | 1 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0039 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0039 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0033 | 0.0039 | 0.5 |
Leishmania major | hypothetical protein | 0.0033 | 0.0039 | 0.5 |
Trypanosoma brucei | tyrosyl-tRNA synthetase, putative | 0.0033 | 0.0039 | 0.5 |
Echinococcus granulosus | tyrosyl tRNA synthetase | 0.0033 | 0.0039 | 0.0047 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0033 | 0.0039 | 0.5 |
Trichomonas vaginalis | methionyl-tRNA synthetase, putative | 0.0033 | 0.0039 | 0.5 |
Loa Loa (eye worm) | multisynthetase complex auxiliary component p43 | 0.0202 | 0.8414 | 1 |
Leishmania major | tyrosyl or methionyl-tRNA synthetase-like protein | 0.0033 | 0.0039 | 0.5 |
Schistosoma mansoni | methionyl-tRNA synthetase | 0.0033 | 0.0039 | 0.0047 |
Toxoplasma gondii | methionyl-tRNA synthetase | 0.0065 | 0.1626 | 1 |
Echinococcus multilocularis | tyrosyl tRNA synthetase | 0.0033 | 0.0039 | 0.0047 |
Trypanosoma brucei | tyrosyl/methionyl-tRNA synthetase, putative | 0.0033 | 0.0039 | 0.5 |
Mycobacterium ulcerans | phenylalanyl-tRNA synthetase subunit beta | 0.0033 | 0.0039 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.687 | 0.8225 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1865 | 0.2217 |
Schistosoma mansoni | methionine-tRNA synthetase | 0.0201 | 0.8353 | 1 |
Trypanosoma cruzi | tyrosyl or methionyl-tRNA synthetase, putative | 0.0033 | 0.0039 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0033 | 0.0039 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.007 | 0.1865 | 0.1865 |
Mycobacterium tuberculosis | Probable phenylalanyl-tRNA synthetase, beta chain PheT | 0.0033 | 0.0039 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.3473 | 0.4127 |
Echinococcus granulosus | geminin | 0.0171 | 0.687 | 0.8225 |
Trypanosoma cruzi | tyrosyl or methionyl-tRNA synthetase, putative | 0.0033 | 0.0039 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0033 | 0.0039 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.