Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.2563 | 0.1195 |
Trypanosoma cruzi | endonuclease G, putative | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | endonuclease G, putative | 0.0021 | 0 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.003 | 0.1553 | 0.6061 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 1 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0035 | 0.2563 | 0.2563 |
Echinococcus granulosus | ectonucleotide | 0.003 | 0.1553 | 0.6061 |
Trypanosoma brucei | endonuclease G, putative | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.2563 | 0.1195 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 1 |
Leishmania major | endonuclease G, putative | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | DNA/RNA non-specific endonuclease protein-like, putative | 0.0021 | 0 | 0.5 |
Onchocerca volvulus | 0.0076 | 1 | 1 | |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0035 | 0.2563 | 0.2563 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0035 | 0.2563 | 0.2563 |
Trypanosoma brucei | endonuclease G, putative | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0076 | 1 | 1 |
Echinococcus multilocularis | ectonucleotide | 0.003 | 0.1553 | 0.6061 |
Toxoplasma gondii | DNA/RNA non-specific endonuclease | 0.0021 | 0 | 0.5 |
Trypanosoma brucei | endonuclease G, putative | 0.0021 | 0 | 0.5 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 1 |
Brugia malayi | Type I phosphodiesterase / nucleotide pyrophosphatase family protein | 0.0035 | 0.2563 | 0.2563 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.003 | 0.1553 | 0.6061 |
Schistosoma mansoni | ectonucleotide pyrophosphatase/phosphodiesterase | 0.0035 | 0.2563 | 0.2563 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 1 |
Leishmania major | DNA/RNA non-specific endonuclease-like protein | 0.0021 | 0 | 0.5 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 1 |
Echinococcus granulosus | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 1 |
Echinococcus multilocularis | ectonucleotide pyrophosphatase:phosphodiesterase | 0.0035 | 0.2563 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.2563 | 0.1195 |
Loa Loa (eye worm) | thrombospondin type 1 domain-containing protein | 0.0076 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.