Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Animal haem peroxidase family protein | 0.0164 | 0.4964 | 0.4964 |
Schistosoma mansoni | peroxidasin | 0.0164 | 0.4964 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.4964 | 0.4964 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.006 | 0.0691 | 0.0691 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0286 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0164 | 0.4964 | 0.4964 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0043 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.4964 | 0.4964 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.4964 | 0.4964 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0043 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.4964 | 0.4964 |
Brugia malayi | Animal haem peroxidase family protein | 0.0164 | 0.4964 | 0.4964 |
Mycobacterium ulcerans | beta-lactamase | 0.0043 | 0 | 0.5 |
Mycobacterium leprae | Probable lipase LipE | 0.0043 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.4964 | 0.4964 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.4964 | 0.4964 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.4964 | 0.4964 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.4964 | 0.4964 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0278 | 0.9679 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.4964 | 0.4964 |
Brugia malayi | Peroxidasin | 0.0164 | 0.4964 | 0.4964 |
Trichomonas vaginalis | esterase, putative | 0.0043 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0691 | 0.0691 |
Echinococcus granulosus | peroxidasin | 0.0164 | 0.4964 | 0.4964 |
Onchocerca volvulus | Peroxidasin homolog | 0.0164 | 0.4964 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0043 | 0 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0164 | 0.4964 | 0.4964 |
Onchocerca volvulus | Dual oxidase homolog | 0.0164 | 0.4964 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.4964 | 0.4964 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0043 | 0 | 0.5 |
Schistosoma mansoni | peroxidasin | 0.0164 | 0.4964 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0043 | 0 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.006 | 0.0691 | 0.0691 |
Mycobacterium ulcerans | lipase LipD | 0.0043 | 0 | 0.5 |
Onchocerca volvulus | Peroxidase homolog | 0.0164 | 0.4964 | 1 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0058 | 0.061 | 0.061 |
Toxoplasma gondii | ABC1 family protein | 0.0043 | 0 | 0.5 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0164 | 0.4964 | 0.4964 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0043 | 0 | 0.5 |
Brugia malayi | Blistered cuticle protein 3 | 0.0164 | 0.4964 | 0.4964 |
Schistosoma mansoni | survival motor neuron protein | 0.0058 | 0.061 | 0.1229 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.4964 | 0.4964 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.4964 | 0.4964 |
Onchocerca volvulus | 0.0164 | 0.4964 | 1 | |
Brugia malayi | hypothetical protein | 0.0164 | 0.4964 | 0.4964 |
Schistosoma mansoni | hypothetical protein | 0.0058 | 0.061 | 0.1229 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0164 | 0.4964 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.006 | 0.0691 | 0.0691 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0286 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0043 | 0 | 0.5 |
Echinococcus multilocularis | peroxidasin | 0.0164 | 0.4964 | 0.4964 |
Onchocerca volvulus | 0.0164 | 0.4964 | 1 | |
Onchocerca volvulus | 0.0058 | 0.061 | 0.1229 | |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.4964 | 0.4964 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0043 | 0 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0164 | 0.4964 | 0.4964 |
Onchocerca volvulus | 0.0164 | 0.4964 | 1 | |
Onchocerca volvulus | Peroxidase homolog | 0.0164 | 0.4964 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0164 | 0.4964 | 0.4964 |
Loa Loa (eye worm) | hypothetical protein | 0.0286 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0164 | 0.4964 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.4964 | 0.4964 |
Brugia malayi | Animal haem peroxidase family protein | 0.0164 | 0.4964 | 0.4964 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0164 | 0.4964 | 0.4964 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0164 | 0.4964 | 0.4964 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0043 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.