Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0027 | 0.0597 | 0.0597 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0027 | 0.0597 | 0.0597 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0161 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.004 | 0.1473 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.004 | 0.1473 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.004 | 0.1473 | 0.0931 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.004 | 0.1473 | 0.1473 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.004 | 0.1473 | 0.0931 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Brugia malayi | Cathepsin L-like precursor | 0.004 | 0.1473 | 0.1473 |
Brugia malayi | Cathepsin L-like precursor | 0.004 | 0.1473 | 0.1473 |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.0597 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1473 | 0.1473 |
Brugia malayi | Cathepsin L-like precursor | 0.0031 | 0.0876 | 0.0876 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0597 | 0.0597 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0031 | 0.0876 | 0.0876 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.004 | 0.1473 | 0.1473 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0161 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.0597 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Echinococcus granulosus | cathepsin L | 0.0027 | 0.0597 | 0.0597 |
Plasmodium vivax | unspecified product | 0.0027 | 0.0597 | 0.4054 |
Onchocerca volvulus | 0.004 | 0.1473 | 1 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0161 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0031 | 0.0876 | 0.5946 |
Onchocerca volvulus | 0.004 | 0.1473 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.0597 | 0.4054 |
Plasmodium vivax | vivapain-2 | 0.004 | 0.1473 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.004 | 0.1473 | 0.1473 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0876 | 0.0876 |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.0597 | 0.4054 |
Echinococcus granulosus | cathepsin b | 0.0161 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0027 | 0.0597 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0876 | 0.0876 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0876 | 0.0876 |
Loa Loa (eye worm) | cysteine protease | 0.004 | 0.1473 | 0.1473 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0027 | 0.0597 | 0.0597 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.004 | 0.1473 | 0.1473 |
Onchocerca volvulus | 0.004 | 0.1473 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0161 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.004 | 0.1473 | 0.0931 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Plasmodium vivax | vivapain-3 | 0.0027 | 0.0597 | 0.4054 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.004 | 0.1473 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.004 | 0.1473 | 0.1473 |
Toxoplasma gondii | cathepsin B | 0.0161 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.0597 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.004 | 0.1473 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0161 | 1 | 1 |
Onchocerca volvulus | 0.0031 | 0.0876 | 0.5946 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.004 | 0.1473 | 0.1473 |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.0597 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.004 | 0.1473 | 0.1473 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0031 | 0.0876 | 0.0876 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.004 | 0.1473 | 0.1473 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.004 | 0.1473 | 0.1473 |
Echinococcus multilocularis | cysteine protease | 0.004 | 0.1473 | 0.1473 |
Toxoplasma gondii | cathepsin CPL | 0.004 | 0.1473 | 0.1473 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.004 | 0.1473 | 0.0931 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0027 | 0.0597 | 0.4054 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0161 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0161 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.004 | 0.1473 | 0.0931 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0161 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0027 | 0.0597 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.0597 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0031 | 0.0876 | 0.0876 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0161 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0027 | 0.0597 | 0.0597 |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.0597 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.004 | 0.1473 | 0.1473 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Brugia malayi | cathepsin L-like precursor | 0.0031 | 0.0876 | 0.0876 |
Entamoeba histolytica | cysteine protease, putative | 0.004 | 0.1473 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.004 | 0.1473 | 0.1473 |
Giardia lamblia | Cathepsin B precursor | 0.0161 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.004 | 0.1473 | 0.1473 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0027 | 0.0597 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.0597 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Onchocerca volvulus | Cathepsin L homolog | 0.004 | 0.1473 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0031 | 0.0876 | 0.0876 |
Loa Loa (eye worm) | fibroinase | 0.004 | 0.1473 | 0.1473 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0161 | 1 | 1 |
Echinococcus multilocularis | cathepsin L | 0.0027 | 0.0597 | 0.0597 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.004 | 0.1473 | 0.0931 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.004 | 0.1473 | 1 |
Plasmodium vivax | vivapain-2 | 0.004 | 0.1473 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.004 | 0.1473 | 0.0931 |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.0597 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.004 | 0.1473 | 0.0931 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.004 | 0.1473 | 0.1473 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.004 | 0.1473 | 0.0931 |
Loa Loa (eye worm) | ctsf protein | 0.004 | 0.1473 | 0.1473 |
Onchocerca volvulus | 0.004 | 0.1473 | 1 | |
Onchocerca volvulus | 0.004 | 0.1473 | 1 | |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0027 | 0.0597 | 0.0597 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Onchocerca volvulus | 0.004 | 0.1473 | 1 | |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0027 | 0.0597 | 0.0597 |
Trypanosoma cruzi | cysteine protease, putative | 0.0027 | 0.0597 | 0.0597 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.004 | 0.1473 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.004 | 0.1473 | 0.0931 |
Brugia malayi | Cathepsin L-like precursor | 0.004 | 0.1473 | 0.1473 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Echinococcus granulosus | cathepsin l1 | 0.0031 | 0.0876 | 0.0876 |
Brugia malayi | Cathepsin L-like precursor | 0.004 | 0.1473 | 0.1473 |
Onchocerca volvulus | 0.004 | 0.1473 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.0597 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0027 | 0.0597 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Echinococcus multilocularis | cysteine protease | 0.004 | 0.1473 | 0.1473 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.004 | 0.1473 | 0.0931 |
Giardia lamblia | Cathepsin B precursor | 0.0161 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.0597 | 0.4054 |
Echinococcus granulosus | cysteine protease | 0.0027 | 0.0597 | 0.0597 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.004 | 0.1473 | 0.1473 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0597 | 0.0597 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0027 | 0.0597 | 0.0597 |
Echinococcus multilocularis | cathepsin b | 0.0161 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.0597 | 0.4054 |
Loa Loa (eye worm) | cathepsin B | 0.0161 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0027 | 0.0597 | 0.4054 |
Plasmodium vivax | vivapain-1 | 0.0027 | 0.0597 | 0.4054 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0161 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0031 | 0.0876 | 0.0876 |
Brugia malayi | Cathepsin L-like precursor | 0.0031 | 0.0876 | 0.0876 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0027 | 0.0597 | 0.0597 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0027 | 0.0597 | 0.4054 |
Onchocerca volvulus | Cathepsin L homolog | 0.004 | 0.1473 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.0597 | 0.0597 |
Giardia lamblia | Cathepsin B precursor | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.1473 | 0.1473 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.004 | 0.1473 | 0.1473 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0027 | 0.0597 | 0.0597 |
Echinococcus granulosus | cathepsin b | 0.0161 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.004 | 0.1473 | 0.1473 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.