TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 325.36 | Formula: C22H15NO2
H donors: 2 H acceptors: 3 LogP: 4.07 Rotable bonds: 2
Rule of 5 violations (Lipinski): 1
SMILES: N#Cc1ccc(cc1)C1=C(c2ccc(cc2)O)c2c(C1)cc(cc2)O
InChi: 1S/C22H15NO2/c23-13-14-1-3-15(4-2-14)21-12-17-11-19(25)9-10-20(17)22(21)16-5-7-18(24)8-6-16/h1-11,24-25H,12H2
InChiKey: SNNGUJCURSLZOL-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Onchocerca volvulus	Cathepsin L homolog	0.0084	0.0703	0.4611
Loa Loa (eye worm)	inward rectifying k channel family protein 1	0.0887	1	1
Leishmania major	cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like	0.0158	0.1552	1
Brugia malayi	Cathepsin L-like precursor	0.0084	0.0703	0.1422
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0084	0.0703	0.4419
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0084	0.0703	0.4419
Schistosoma mansoni	hypothetical protein	0.0034	0.0125	0.0252
Plasmodium vivax	vivapain-2	0.0084	0.0703	1
Echinococcus granulosus	cysteine protease	0.005	0.0304	0.0554
Loa Loa (eye worm)	fibroinase	0.0084	0.0703	0.0703
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0084	0.0703	1
Echinococcus multilocularis	cathepsin L cysteine protease	0.0084	0.0703	0.1367
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0026	0.0032	0.0064
Brugia malayi	Papain family cysteine protease containing protein	0.0084	0.0703	0.1422
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0451	0.4947	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0084	0.0703	0.4419
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0084	0.0703	0.4419
Entamoeba histolytica	cysteine protease, putative	0.005	0.0304	0.4054
Loa Loa (eye worm)	cathepsin B	0.0158	0.1552	0.1552
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0084	0.0703	1
Echinococcus granulosus	cathepsin b	0.0451	0.4947	1
Brugia malayi	Calcitonin receptor-like protein seb-1	0.005	0.0309	0.0624
Brugia malayi	Cathepsin L-like precursor	0.0061	0.0431	0.0871
Echinococcus multilocularis	cathepsin L	0.005	0.0304	0.0554
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0061	0.0431	0.2627
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0032	0.0032
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.0026	0.0032	0.0451
Onchocerca volvulus	Cathepsin F homolog	0.0084	0.0703	0.4611
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.005	0.0304	0.0615
Toxoplasma gondii	hypothetical protein	0.0887	1	1
Brugia malayi	cathepsin B-like cysteine proteinase	0.0451	0.4947	1
Loa Loa (eye worm)	hypothetical protein	0.0887	1	1
Plasmodium vivax	serine-repeat antigen 5 (SERA)	0.0026	0.0032	0.0451
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0026	0.0032	0.0064
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0061	0.0431	0.0871
Brugia malayi	latrophilin 2 splice variant baaae	0.0034	0.0125	0.0252
Onchocerca volvulus		0.0061	0.0431	0.2742
Plasmodium vivax	dipeptidyl aminopeptidase 2, putative	0.0026	0.0032	0.0451
Plasmodium vivax	serine-repeat antigen 4 (SERA), putative	0.0026	0.0032	0.0451
Schistosoma mansoni	dipeptidyl-peptidase I (C01 family)	0.0026	0.0032	0.0064
Brugia malayi	cathepsin F-like cysteine proteinase	0.0026	0.0032	0.0064
Trypanosoma cruzi	cruzipain precursor, putative	0.0084	0.0703	0.1422
Plasmodium vivax	serine-repeat antigen 4 (SERA)	0.0026	0.0032	0.0451
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0158	0.1552	0.3137
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0026	0.0032	0.0032
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0084	0.0703	0.4419
Entamoeba histolytica	cysteine protease, putative	0.005	0.0304	0.4054
Entamoeba histolytica	cysteine proteinase 1, putative	0.005	0.0304	0.4054
Giardia lamblia	Cathepsin B precursor	0.0158	0.1552	1
Entamoeba histolytica	cysteine proteinase, putative	0.005	0.0304	0.4054
Echinococcus granulosus	cathepsin b	0.0451	0.4947	1
Brugia malayi	hypothetical protein	0.0152	0.1488	0.3009
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.005	0.0304	0.1791
Brugia malayi	Papain family cysteine protease containing protein	0.0026	0.0032	0.0064
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0084	0.0703	0.4419
Entamoeba histolytica	cysteine protease, putative	0.0084	0.0703	1
Entamoeba histolytica	cysteine protease, putative	0.005	0.0304	0.4054
Toxoplasma gondii	cathepsin CPL	0.0084	0.0703	0.0674
Entamoeba histolytica	cysteine protease, putative	0.005	0.0304	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0158	0.1552	1
Giardia lamblia	Cathepsin B precursor	0.0158	0.1552	1
Onchocerca volvulus		0.0084	0.0703	0.4611
Toxoplasma gondii	cathepsin B	0.0158	0.1552	0.1525
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.005	0.0309	0.0309
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0032	0.0032
Schistosoma mansoni	cathepsin F (C01 family)	0.0084	0.0703	0.1422
Onchocerca volvulus		0.0084	0.0703	0.4611
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.005	0.0304	0.0615
Loa Loa (eye worm)	hypothetical protein	0.0887	1	1
Onchocerca volvulus		0.0084	0.0703	0.4611
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.005	0.0304	0.0615
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0084	0.0703	0.1367
Entamoeba histolytica	cysteine protease, putative	0.005	0.0304	0.4054
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0158	0.1552	0.3137
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0084	0.0703	0.4419
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0084	0.0703	0.1367
Trypanosoma brucei	cysteine peptidase C (CPC)	0.0158	0.1552	1
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0084	0.0703	0.1367
Loa Loa (eye worm)	hypothetical protein	0.0084	0.0703	0.0703
Echinococcus multilocularis	cathepsin L cysteine protease	0.0084	0.0703	0.1367
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0084	0.0703	0.1367
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0032	0.0032
Echinococcus multilocularis	cysteine protease	0.0084	0.0703	0.1367
Echinococcus granulosus	cathepsin l1	0.0061	0.0431	0.0813
Trypanosoma cruzi	cysteine protease, putative	0.005	0.0304	0.0615
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0026	0.0032	0.0064
Plasmodium vivax	vivapain-3	0.005	0.0304	0.4322
Loa Loa (eye worm)	hypothetical protein	0.0451	0.4947	0.4947
Loa Loa (eye worm)	hypothetical protein	0.005	0.0309	0.0309
Trypanosoma cruzi	cysteine proteinase, putative	0.005	0.0304	0.0615
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0084	0.0703	0.4419
Schistosoma mansoni	cathepsin F (C01 family)	0.0061	0.0431	0.0871
Brugia malayi	Cathepsin L-like precursor	0.0084	0.0703	0.1422
Plasmodium vivax	dipeptidyl aminopeptidase 3, putative	0.0026	0.0032	0.0451
Brugia malayi	Papain family cysteine protease containing protein	0.005	0.0304	0.0615
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0431	0.0431
Plasmodium vivax	unspecified product	0.005	0.0304	0.4322
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0084	0.0703	0.4419
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0084	0.0703	0.4419
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0084	0.0703	0.4419
Brugia malayi	Papain family cysteine protease containing protein	0.0026	0.0032	0.0064
Schistosoma mansoni	cathepsin C	0.0026	0.0032	0.0064
Brugia malayi	Cathepsin L-like precursor	0.0084	0.0703	0.1422
Echinococcus granulosus	cathepsin l1	0.0084	0.0703	0.1367
Echinococcus multilocularis	cysteine protease	0.0084	0.0703	0.1367
Onchocerca volvulus		0.0084	0.0703	0.4611
Brugia malayi	cathepsin L-like precursor	0.0061	0.0431	0.0871
Schistosoma mansoni	cathepsin S (C01 family)	0.0026	0.0032	0.0064
Brugia malayi	Cathepsin L-like precursor	0.0061	0.0431	0.0871
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0084	0.0703	0.4419
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0084	0.0703	0.3201
Trypanosoma cruzi	cysteine peptidase, putative	0.005	0.0304	0.0615
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0026	0.0032	0.0064
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0032	0.0032
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.005	0.0304	0.1791
Plasmodium falciparum	cysteine proteinase falcipain 1	0.005	0.0304	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0084	0.0703	0.4419
Entamoeba histolytica	cysteine proteinase, putative	0.0084	0.0703	1
Entamoeba histolytica	cysteine protease, putative	0.005	0.0304	0.4054
Trypanosoma cruzi	major cysteine proteinase, putative	0.0026	0.0032	0.0064
Trypanosoma cruzi	cysteine peptidase, putative	0.0084	0.0703	0.1422
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0125	0.0125
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0026	0.0032	0.0064
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0084	0.0703	0.4419
Plasmodium vivax	dipeptidyl aminopeptidase 1, putative	0.0026	0.0032	0.0451
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0084	0.0703	0.3201
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0061	0.0431	0.2627
Onchocerca volvulus		0.0084	0.0703	0.4611
Echinococcus multilocularis	cathepsin b	0.0451	0.4947	1
Brugia malayi	Papain family cysteine protease containing protein	0.005	0.0304	0.0615
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0084	0.0703	0.4419
Plasmodium vivax	serine-repeat antigen 3 (SERA)	0.0026	0.0032	0.0451
Entamoeba histolytica	cysteine protease, putative	0.005	0.0304	0.4054
Loa Loa (eye worm)	cysteine protease	0.0084	0.0703	0.0703
Brugia malayi	Papain family cysteine protease containing protein	0.0026	0.0032	0.0064
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0084	0.0703	0.0703
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0084	0.0703	0.4419
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0026	0.0032	0.0064
Entamoeba histolytica	cysteine proteinase, putative	0.0084	0.0703	1
Echinococcus granulosus	cathepsin L	0.005	0.0304	0.0554
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0084	0.0703	0.3201
Entamoeba histolytica	cysteine protease, putative	0.005	0.0304	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0084	0.0703	0.4419
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0084	0.0703	0.4419
Loa Loa (eye worm)	cysteine proteinase cathepsin Z	0.0026	0.0032	0.0032
Plasmodium vivax	unspecified product	0.0026	0.0032	0.0451
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0084	0.0703	0.4419
Entamoeba histolytica	cysteine protease, putative	0.005	0.0304	0.4054
Plasmodium vivax	serine-repeat antigen 2 (SERA)	0.0026	0.0032	0.0451
Plasmodium vivax	vivapain-2	0.0084	0.0703	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0451	0.4947	1
Giardia lamblia	Cathepsin B precursor	0.0158	0.1552	1
Brugia malayi	cathepsin L precursor	0.0026	0.0032	0.0064
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0084	0.0703	0.3201
Entamoeba histolytica	cysteine protease, putative	0.005	0.0304	0.4054
Trypanosoma cruzi	cysteine peptidase, putative	0.0084	0.0703	0.1422
Entamoeba histolytica	cysteine proteinase, putative	0.005	0.0304	0.4054
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0084	0.0703	0.4419
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0084	0.0703	0.3201
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.005	0.0309	0.0624
Schistosoma mansoni	cathepsin F (C01 family)	0.0084	0.0703	0.1422
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0084	0.0703	0.4419
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0032	0.0032
Entamoeba histolytica	cysteine proteinase, putative	0.005	0.0304	0.4054
Onchocerca volvulus		0.0084	0.0703	0.4611
Echinococcus granulosus	cathepsin L cysteine protease	0.005	0.0304	0.0554
Onchocerca volvulus		0.0152	0.1488	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0084	0.0703	0.4419
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0084	0.0703	0.3201
Plasmodium vivax	serine-repeat antigen (SERA)	0.0026	0.0032	0.0451
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0431	0.0431
Onchocerca volvulus		0.0084	0.0703	0.4611
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0084	0.0703	0.3201
Plasmodium vivax	vivapain-1	0.005	0.0304	0.4322
Entamoeba histolytica	cysteine proteinase, putative	0.005	0.0304	0.4054
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0431	0.0431
Entamoeba histolytica	cysteine proteinase 2	0.005	0.0304	0.4054
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0451	0.4947	1
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.005	0.0304	0.0615
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0084	0.0703	0.3201
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0026	0.0032	0.0064
Brugia malayi	cathepsin L-like cysteine proteinase	0.0026	0.0032	0.0064
Entamoeba histolytica	cysteine proteinase, putative	0.0061	0.0431	0.5946
Trypanosoma cruzi	cysteine peptidase, putative	0.0084	0.0703	0.1422
Onchocerca volvulus	Cathepsin L homolog	0.0084	0.0703	0.4611
Entamoeba histolytica	cysteine protease, putative	0.005	0.0304	0.4054
Trypanosoma cruzi	cysteine proteinase, putative	0.005	0.0304	0.0615
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0451	0.4947	1
Plasmodium vivax	serine-repeat antigen (SERA)	0.0026	0.0032	0.0451
Schistosoma mansoni	subfamily C1A non-peptidase homologue (C01 family)	0.0026	0.0032	0.0064
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0084	0.0703	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0084	0.0703	0.3201
Loa Loa (eye worm)	ctsf protein	0.0084	0.0703	0.0703
Brugia malayi	Cathepsin L-like precursor	0.0084	0.0703	0.1422
Brugia malayi	Cathepsin L-like precursor	0.0084	0.0703	0.1422
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.0451	0.4947	1
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0026	0.0032	0.0032
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0084	0.0703	0.4419
Brugia malayi	cahepsin L-like non-peptiedase homolog	0.0026	0.0032	0.0064
Brugia malayi	Cathepsin L-like precursor	0.0084	0.0703	0.1422
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0061	0.0431	0.0871
Echinococcus multilocularis	cathepsin b	0.0451	0.4947	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0084	0.0703	0.1422
Loa Loa (eye worm)	hypothetical protein	0.0152	0.1488	0.1488
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.0026	0.0032	0.0451
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0084	0.0703	0.3201
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0084	0.0703	0.4419
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0084	0.0703	0.0703
Trypanosoma cruzi	major cysteine proteinase, putative	0.0026	0.0032	0.0064
Schistosoma mansoni	cathepsin B (C01 family)	0.0026	0.0032	0.0064
Brugia malayi	fibroinase precursor	0.0026	0.0032	0.0064
Entamoeba histolytica	cysteine protease, putative	0.005	0.0304	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0084	0.0703	0.4419
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0026	0.0032	0.0064
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0032	0.0032
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0026	0.0032	0.0064
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0084	0.0703	0.3201
Entamoeba histolytica	cysteine protease, putative	0.005	0.0304	0.4054

Activities

Activity type	Activity value	Assay description	Source	Reference
RBA (binding)	= 1 %	Displacement of [3H]-estradiol from estrogen receptor of rat uterine cytosol	ChEMBL.	3411601
RBA (binding)	= 1 %	Displacement of [3H]-estradiol from estrogen receptor of rat uterine cytosol	ChEMBL.	3411601

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

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Detailed information for compound 72800