Detailed information for compound 738376

Basic information

Technical information
  • TDR Targets ID: 738376
  • Name: 3-(8-methoxy-2-methyl-3-propylquinolin-4-yl)s ulfanylpropanoic acid
  • MW: 319.419 | Formula: C17H21NO3S
  • H donors: 1 H acceptors: 3 LogP: 3.91 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCc1c(C)nc2c(c1SCCC(=O)O)cccc2OC
  • InChi: 1S/C17H21NO3S/c1-4-6-12-11(2)18-16-13(7-5-8-14(16)21-3)17(12)22-10-9-15(19)20/h5,7-8H,4,6,9-10H2,1-3H3,(H,19,20)
  • InChiKey: QILDPSFPODIYNC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 3-[(8-methoxy-2-methyl-3-propyl-4-quinolyl)sulfanyl]propanoic acid
  • 3-[(8-methoxy-2-methyl-3-propyl-4-quinolyl)thio]propanoic acid
  • 3-[(8-methoxy-2-methyl-3-propyl-4-quinolyl)thio]propionic acid
  • 3-(8-methoxy-2-methyl-3-propyl-quinolin-4-yl)sulfanylpropanoic acid
  • Oprea1_518043
  • CBKinase1_001446
  • STOCK2S-62406
  • CBKinase1_013846
  • Oprea1_293064

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0176 0.1822
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0107 0.1944
Entamoeba histolytica protein kinase, putative 0.0032 0.0484 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0106 0.0305
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0032 0.0484 0.7919
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0283 0.395
Echinococcus granulosus General substrate transporter 0.0089 0.1821 0.2341
Loa Loa (eye worm) hypothetical protein 0.0015 0.0084 0.0199
Trypanosoma cruzi hexose transporter 0.0032 0.0493 0.8107
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0107 0.0023
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0283 0.0201
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0469 0.0519
Echinococcus multilocularis General substrate transporter 0.0089 0.1821 0.2341
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0283 0.5182
Plasmodium falciparum calcium-dependent protein kinase 1 0.0032 0.0484 0.0404
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0493 0.8107
Loa Loa (eye worm) hypothetical protein 0.0015 0.0106 0.0305
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0107 0.0035
Leishmania major glucose transporter, lmgt3 0.0032 0.0493 0.8107
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0032 0.0484 0.0404
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.0484 0.1927
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0493 0.8107
Plasmodium falciparum calcium-dependent protein kinase 4 0.0032 0.0484 0.0404
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0107 0.0111
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0283 0.0961
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0176 0.1822
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0032 0.0484 0.0404
Trypanosoma brucei glucose transporter 1E 0.0032 0.0493 0.8107
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0103 0.216 0.2799
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.0484 0.0539
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0493 0.8107
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0469 0.0519
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0107 0.0455
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0084 0.0199
Plasmodium falciparum calcium-dependent protein kinase 2 0.0032 0.0484 0.0404
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0283 0.395
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0283 0.395
Schistosoma mansoni hypothetical protein 0.0015 0.0106 0.0108
Loa Loa (eye worm) hypothetical protein 0.0015 0.0084 0.0199
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0176 0.0093
Brugia malayi Cam kinase protein 1 0.0032 0.0484 0.1927
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0106 0.003
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0493 0.8107
Toxoplasma gondii exonuclease III APE 0.0018 0.0176 0.0142
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0589 1
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0589 1
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0484 0.1927
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0107 0.0455
Loa Loa (eye worm) hypothetical protein 0.0015 0.0084 0.0199
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0283 0.0961
Loa Loa (eye worm) hypothetical protein 0.0015 0.0084 0.0199
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0107 0.0111
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0811 0.098
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0176 0.7782
Plasmodium falciparum calcium-dependent protein kinase 3 0.0032 0.0484 0.0404
Echinococcus multilocularis GPCR, family 2 0.0015 0.0106 0.003
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0493 0.1973
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0283 0.0201
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0217 0.0641
Loa Loa (eye worm) hypothetical protein 0.0049 0.0889 0.3998
Brugia malayi Sugar transporter family protein 0.0103 0.216 1
Mycobacterium ulcerans sugar transporter 0.0015 0.0084 0.2954
Echinococcus granulosus GPCR family 2 0.0015 0.0106 0.003
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0469 0.1855
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0469 0.9514
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0032 0.0484 0.0617
Loa Loa (eye worm) hypothetical protein 0.0031 0.0469 0.2017
Schistosoma mansoni protein kinase 0.0032 0.0484 0.1927
Loa Loa (eye worm) hypothetical protein 0.0015 0.0084 0.0199
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0484 0.0539
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.216 0.2799
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0015 0.0084 0.2954
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0889 0.3876
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0084 0.0199
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0484 0.0539
Plasmodium vivax CDK-related protein kinase 6, putative 0.0438 1 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0176 0.0093
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0107 0.0455
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0493 0.1973
Schistosoma mansoni hypothetical protein 0.0103 0.216 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0084 0.0199
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0469 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0106 0.003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0811 0.098
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0176 0.239
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0589 0.051
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0107 0.0031
Trypanosoma brucei glucose transporter, putative 0.0032 0.0493 0.8107
Loa Loa (eye worm) hypothetical protein 0.0033 0.0526 0.2289
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0032 0.0484 0.0404
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0493 0.8107
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0811 0.098
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0493 0.8107
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0484 0.1927
Plasmodium vivax hexose transporter 0.0103 0.216 0.2094
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0107 0.0031
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0176 0.0124
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0176 0.1822
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0493 0.1973
Schistosoma mansoni hypothetical protein 0.0015 0.0106 0.0108
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.216 0.2799
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0283 0.0269
Entamoeba histolytica hypothetical protein 0.0023 0.0283 0.349
Schistosoma mansoni hypothetical protein 0.0015 0.0106 0.0108
Schistosoma mansoni hypothetical protein 0.0033 0.0526 0.2132
Loa Loa (eye worm) hypothetical protein 0.0015 0.0084 0.0199
Mycobacterium ulcerans integral membrane transport protein 0.0015 0.0084 0.2954
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0176 0.0124
Echinococcus granulosus calcium dependent protein kinase 0.003 0.0438 0.0478
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0176 0.1822
Loa Loa (eye worm) hypothetical protein 0.0015 0.0084 0.0199
Brugia malayi isocitrate dehydrogenase 0.0016 0.0107 0.0111
Plasmodium falciparum mitogen-activated protein kinase 2 0.0167 0.3649 0.3595
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0106 0.0108
Loa Loa (eye worm) hypothetical protein 0.0015 0.0084 0.0199
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0493 0.1973
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0107 0.0035
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0283 0.3046
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0283 0.0269
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.216 0.2799
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0589 1
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0167 0.3649 0.5495
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0484 0.0539
Loa Loa (eye worm) hypothetical protein 0.0015 0.0084 0.0199
Trypanosoma brucei glucose transporter, putative 0.0032 0.0493 0.8107
Schistosoma mansoni ap endonuclease 0.0018 0.0176 0.0443
Trypanosoma brucei glucose transporter, putative 0.0032 0.0493 0.8107
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0107 0.0031
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0176 1
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0283 1
Plasmodium vivax calcium-dependent protein kinase, putative 0.0032 0.0484 0.0404
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0469 1
Schistosoma mansoni hypothetical protein 0.0015 0.0106 0.0108
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0589 0.051
Entamoeba histolytica protein kinase, putative 0.0032 0.0484 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0811 0.3502
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0469 0.1855
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0176 0.0443
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0589 1
Schistosoma mansoni glucose transport protein 0.0103 0.216 1
Plasmodium falciparum protein kinase 7 0.0292 0.6571 0.6542
Plasmodium falciparum hexose transporter 0.0103 0.216 0.2094
Trypanosoma brucei glucose transporter, putative 0.0032 0.0493 0.8107
Trypanosoma cruzi hexose transporter, putative 0.0018 0.0154 0.1383
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0493 0.8107
Schistosoma mansoni glucose transport protein 0.0103 0.216 1
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0176 0.0443
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0106 0.0108
Trypanosoma brucei glucose transporter 2A 0.0032 0.0493 0.8107
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0283 0.0308
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0107 0.0455
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0889 0.3998
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0484 0.0539
Loa Loa (eye worm) sugar transporter 0.0015 0.0084 0.0199
Onchocerca volvulus 0.0049 0.088 1
Leishmania major protein kinase, putative 0.0032 0.0484 0.7919
Trypanosoma brucei glucose transporter, putative 0.0032 0.0493 0.8107
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0032 0.0484 0.0617
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0469 0.1855
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0889 0.3876
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0469 0.1855
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0493 0.1973
Trypanosoma brucei glucose transporter, putative 0.0032 0.0493 0.8107
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0811 0.3502
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0283 0.0961
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.0484 0.2088
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0032 0.0484 0.0617
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0811 0.3502
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0484 0.0539
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0589 0.0779
Echinococcus multilocularis tumor protein p63 0.0332 0.7503 1
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0167 0.3649 0.3595
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0589 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0107 0.0031
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0526 0.2132
Toxoplasma gondii protein kinase, putative 0.0292 0.6571 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0484 0.2088
Loa Loa (eye worm) hypothetical protein 0.0049 0.088 0.3955
Loa Loa (eye worm) hypothetical protein 0.0015 0.0084 0.0199
Loa Loa (eye worm) hypothetical protein 0.0015 0.0084 0.0199
Leishmania major glucose transporter, lmgt1 0.0032 0.0493 0.8107
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.216 0.2799
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.216 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0811 0.098
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0107 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0493 0.1973
Loa Loa (eye worm) sugar transporter 0.0103 0.216 1
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0107 0.0455
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0811 0.3631
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0202 1
Schistosoma mansoni ap endonuclease 0.0018 0.0176 0.0443
Toxoplasma gondii facilitative glucose transporter GT1 0.0103 0.216 0.3201
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.088 0.3832
Loa Loa (eye worm) hypothetical protein 0.0023 0.0283 0.1141
Loa Loa (eye worm) hypothetical protein 0.0015 0.0084 0.0199
Loa Loa (eye worm) hypothetical protein 0.0031 0.0469 0.2017
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0106 0.003
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.0438 0.0478
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0176 0.0443
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0107 0.0031
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0493 0.1973
Plasmodium falciparum calcium-dependent protein kinase 5 0.0032 0.0484 0.0404
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.216 0.2799
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0015 0.0084 0.2954
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0283 1
Schistosoma mansoni glucose transport protein 0.0103 0.216 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0106 0.003
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0176 0.0634
Trypanosoma brucei glucose transporter, putative 0.0032 0.0493 0.8107
Leishmania major glucose transporter, lmgt2 0.0032 0.0493 0.8107
Trypanosoma brucei glucose transporter, putative 0.0032 0.0493 0.8107
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0107 0.0031
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0484 0.0539
Loa Loa (eye worm) hypothetical protein 0.0025 0.0333 0.1375
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.216 0.2799
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0283 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0176 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0084 0.0199
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0283 0.0961
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0176 0.6204
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0107 0.0308
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0469 0.1855
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0484 0.0539
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0811 0.3502
Loa Loa (eye worm) hypothetical protein 0.0015 0.0084 0.0199
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0202 1
Schistosoma mansoni protein kinase 0.0032 0.0484 0.1927
Echinococcus granulosus tumor protein p63 0.0332 0.7503 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.216 0.2799
Schistosoma mansoni protein kinase 0.0032 0.0484 0.1927
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.0484 0.2088

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.