Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0028 | 1 | 0.5 | |
Echinococcus multilocularis | lamin | 0.0028 | 1 | 1 |
Schistosoma mansoni | DNA helicase recq1 | 0.002 | 0.5856 | 0.5856 |
Entamoeba histolytica | recQ family helicase, putative | 0.002 | 0.5856 | 1 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.002 | 0.5856 | 0.4877 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.1625 | 0.1434 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.002 | 0.5856 | 0.4877 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.002 | 0.5856 | 0.5761 |
Treponema pallidum | ATP-dependent DNA helicase | 0.001 | 0.0223 | 0.5 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.002 | 0.5856 | 0.5 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.002 | 0.5856 | 0.5 |
Loa Loa (eye worm) | RecQ helicase | 0.002 | 0.5856 | 0.5761 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.002 | 0.5856 | 0.5 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.5856 | 0.4291 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.5856 | 0.5761 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.002 | 0.5856 | 0.4877 |
Entamoeba histolytica | recQ family DNA helicase | 0.001 | 0.0223 | 0.0381 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.002 | 0.5856 | 0.4877 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.001 | 0.0223 | 1 |
Schistosoma mansoni | DNA helicase recq5 | 0.002 | 0.5856 | 0.5856 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.001 | 0.0223 | 0.0223 |
Echinococcus multilocularis | bloom syndrome protein | 0.002 | 0.5856 | 0.4877 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.002 | 0.5856 | 0.5 |
Echinococcus multilocularis | musashi | 0.0028 | 1 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.5856 | 1 |
Brugia malayi | Bloom's syndrome protein homolog | 0.002 | 0.5856 | 0.4291 |
Onchocerca volvulus | 0.0028 | 1 | 0.5 | |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.002 | 0.5856 | 0.5 |
Echinococcus granulosus | lamin | 0.0028 | 1 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 1 | 1 |
Schistosoma mansoni | lamin | 0.0028 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.1625 | 0.1434 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 1 | 1 |
Schistosoma mansoni | lamin | 0.0028 | 1 | 1 |
Echinococcus granulosus | bloom syndrome protein | 0.002 | 0.5856 | 0.4877 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.5856 | 0.4291 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0223 | 0.0000000048454 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.002 | 0.5856 | 0.5 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 1 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.5856 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 1 | 1 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.002 | 0.5856 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.1911 | 0.1727 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0223 | 0.0381 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 1 | 1 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.2742 | 0.2576 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.002 | 0.5856 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.9714 | 0.9707 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 1 | 1 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.002 | 0.5856 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.