Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | lamin | 0.0028 | 1 | 1 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.001 | 0.0223 | 1 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.002 | 0.5856 | 0.5 |
Schistosoma mansoni | lamin | 0.0028 | 1 | 1 |
Brugia malayi | Bloom's syndrome protein homolog | 0.002 | 0.5856 | 0.4291 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.5856 | 0.4291 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.002 | 0.5856 | 0.5 |
Loa Loa (eye worm) | RecQ helicase | 0.002 | 0.5856 | 0.5761 |
Echinococcus granulosus | lamin | 0.0028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.1625 | 0.1434 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.002 | 0.5856 | 0.5 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.002 | 0.5856 | 0.4877 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.002 | 0.5856 | 0.5 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.2742 | 0.2576 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0223 | 0.0000000048454 |
Entamoeba histolytica | recQ family helicase, putative | 0.002 | 0.5856 | 1 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.002 | 0.5856 | 0.5 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.001 | 0.0223 | 0.0223 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.9714 | 0.9707 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 1 | 1 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.002 | 0.5856 | 0.4877 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.002 | 0.5856 | 1 |
Echinococcus multilocularis | bloom syndrome protein | 0.002 | 0.5856 | 0.4877 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 1 | 1 |
Onchocerca volvulus | 0.0028 | 1 | 0.5 | |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0223 | 0.0381 |
Entamoeba histolytica | recQ family DNA helicase | 0.001 | 0.0223 | 0.0381 |
Schistosoma mansoni | lamin | 0.0028 | 1 | 1 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.002 | 0.5856 | 0.4877 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 1 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.5856 | 0.5761 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 1 | 1 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.5856 | 1 |
Treponema pallidum | ATP-dependent DNA helicase | 0.001 | 0.0223 | 0.5 |
Echinococcus granulosus | bloom syndrome protein | 0.002 | 0.5856 | 0.4877 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.1625 | 0.1434 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.002 | 0.5856 | 0.5 |
Schistosoma mansoni | DNA helicase recq1 | 0.002 | 0.5856 | 0.5856 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.1911 | 0.1727 |
Schistosoma mansoni | DNA helicase recq5 | 0.002 | 0.5856 | 0.5856 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.002 | 0.5856 | 0.5 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.5856 | 0.4291 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 1 | 1 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.002 | 0.5856 | 0.5 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.5856 | 1 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.002 | 0.5856 | 0.5761 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.002 | 0.5856 | 0.4877 |
Onchocerca volvulus | 0.0028 | 1 | 0.5 | |
Echinococcus multilocularis | musashi | 0.0028 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.