Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | chromobox protein, putative | 0.0035 | 0.0436 | 0.0838 |
Trichomonas vaginalis | chromobox protein, putative | 0.0058 | 0.1453 | 0.8656 |
Trichomonas vaginalis | chromobox protein, putative | 0.0035 | 0.0436 | 0.0838 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0016 | 0.005 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0035 | 0.0452 | 0.0452 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0099 | 0.3282 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0327 | 0.0996 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0093 | 0.2996 | 1 |
Brugia malayi | Melibiase family protein | 0.0062 | 0.1628 | 0.4961 |
Brugia malayi | chromobox protein homolog 3 | 0.0032 | 0.0327 | 0.0996 |
Mycobacterium ulcerans | hypothetical protein | 0.0132 | 0.4742 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.004 | 0.0682 | 0.2277 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0099 | 0.3282 | 1 |
Echinococcus multilocularis | Alpha N acetylgalactosaminidase | 0.0093 | 0.2996 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0251 | 1 | 1 |
Echinococcus granulosus | Alpha N acetylgalactosaminidase | 0.0093 | 0.2996 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0251 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0083 | 0.2587 | 0.7349 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0083 | 0.2587 | 0.7349 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0083 | 0.2587 | 0.7349 |
Brugia malayi | Heterochromatin protein 1 | 0.0058 | 0.1453 | 0.4428 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0132 | 0.4742 | 0.5 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0093 | 0.2996 | 1 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0119 | 0.4148 | 0.4148 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0083 | 0.2587 | 0.7882 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0035 | 0.0452 | 0.0452 |
Trichomonas vaginalis | alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative | 0.0062 | 0.1628 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0032 | 0.0327 | 0.7399 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0083 | 0.2587 | 0.7349 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0083 | 0.2587 | 0.7882 |
Echinococcus multilocularis | Glycoside hydrolase, family 27 | 0.0093 | 0.2996 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0035 | 0.0436 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0083 | 0.2587 | 0.7349 |
Brugia malayi | MH2 domain containing protein | 0.0099 | 0.3282 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0062 | 0.1628 | 0.1134 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0093 | 0.2996 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0093 | 0.2996 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0083 | 0.2587 | 0.7349 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.1628 | 0.4961 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0043 | 0.0794 | 0.0794 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0119 | 0.4148 | 0.4148 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0251 | 1 | 1 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0058 | 0.1453 | 0.4428 |
Trichomonas vaginalis | chromobox protein, putative | 0.0058 | 0.1453 | 0.8656 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0 | 0.5 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0119 | 0.4148 | 0.4148 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0083 | 0.2587 | 0.7349 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0035 | 0.0452 | 0.0452 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0035 | 0.0452 | 0.0452 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0062 | 0.1628 | 0.1134 |
Toxoplasma gondii | melibiase subfamily protein | 0.0093 | 0.2996 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.