Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | ubiquinol-cytochrome c reductase complex 14kD subunit, putative | 0.0078 | 0.0865 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0726 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0078 | 0.0865 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0505 | 0.3289 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0726 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0505 | 0.3289 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.2279 | 0.2279 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0271 | 0.0271 |
Plasmodium vivax | ubiquinol-cytochrome c reductase complex subunit, putative | 0.0078 | 0.0865 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0126 | 0.1537 | 0.3382 |
Toxoplasma gondii | ubiquinol-cytochrome c reductase | 0.0078 | 0.0865 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0339 | 0.4543 | 1 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0007 | 0.0048 |
Brugia malayi | hypothetical protein | 0.0027 | 0.014 | 0.091 |
Echinococcus multilocularis | Ubiquinol cytochrome c reductase complex 14 kDa | 0.0339 | 0.4543 | 0.4543 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.014 | 0.0308 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0505 | 0.1112 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0126 | 0.1537 | 0.3382 |
Schistosoma mansoni | Ubiquinol-cytochrome c reductase complex 14 kDa protein | 0.0339 | 0.4543 | 0.4543 |
Echinococcus granulosus | geminin | 0.0178 | 0.2279 | 0.2279 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.2279 | 0.2279 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0505 | 0.1112 |
Trypanosoma brucei | ubiquinol-cytochrome c reductase complex 14 kda protein | 0.0078 | 0.0865 | 1 |
Echinococcus multilocularis | geminin | 0.0178 | 0.2279 | 0.2279 |
Brugia malayi | MH2 domain containing protein | 0.0126 | 0.1537 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0271 | 0.1767 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0271 | 0.0598 |
Plasmodium falciparum | cytochrome b-c1 complex subunit 7, putative | 0.0078 | 0.0865 | 1 |
Echinococcus granulosus | Ubiquinol cytochrome c reductase complex 14 kDa | 0.0339 | 0.4543 | 0.4543 |
Trypanosoma cruzi | ubiquinol-cytochrome c reductase complex 14kD subunit, putative | 0.0078 | 0.0865 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.