Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | calcium activated potassium channel | 0.0221 | 0.0033 | 0.0033 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0221 | 0.0033 | 0.0033 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0221 | 0.0033 | 0.0033 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0221 | 0.0033 | 0.0033 |
Echinococcus multilocularis | serine:threonine protein kinase MARK2 | 0.0221 | 0.0033 | 0.0033 |
Echinococcus granulosus | maternal embryonic leucine zipper kinase | 0.0444 | 0.4413 | 0.4394 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0728 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0663 | 0.8727 | 1 |
Schistosoma mansoni | serine/threonine kinase | 0.0663 | 0.8727 | 0.8727 |
Echinococcus multilocularis | serine:threonine protein kinase MARK2 | 0.0221 | 0.0033 | 0.0033 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0728 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0663 | 0.8727 | 1 |
Loa Loa (eye worm) | CAMK/CAMKL/MELK protein kinase | 0.0663 | 0.8727 | 1 |
Echinococcus multilocularis | maternal embryonic leucine zipper kinase | 0.0444 | 0.4413 | 0.4413 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0221 | 0.0033 | 0.0033 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0221 | 0.0033 | 0.0033 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.